Tadalafil appartiene alla classe degli inibitori selettivi della fosfodiesterasi di tipo 5, con un profilo farmacocinetico caratterizzato da un’emivita terminale di circa diciotto ore. Dopo somministrazione orale viene assorbito rapidamente e raggiunge concentrazioni plasmatiche massime in due ore. La biotrasformazione avviene principalmente tramite CYP3A4 con formazione di metaboliti inattivi, escreti in prevalenza con le feci. L’elevato legame alle proteine plasmatiche (>90%) assicura una distribuzione stabile. Nei confronti delle altre molecole della stessa classe, cialis compresse italia è noto per la durata prolungata dell’attività farmacologica.
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MANUFACTURER’S COUPON EXPIRES APRIL 30, 2007 MANUFACTURER’S COUPON EXPIRES APRIL 30, 2007 MANUFACTURER’S COUPON EXPIRES APRIL 30, 2007 MANUFACTURER’S COUPON EXPIRES APRIL 30, 2007 SAVE?ON?TRUSTED?BRANDS: Benadryl®, Sudafed PE®, Sudafed® & SudaCare® Benadryl® Product Sudafed PE® Product Sudafed® Product SAVE $150 TM SudaCare® Product SAVE $100 SAVE $100 Soothing, Non-Medicated Gentle CareCONSUMER: Limit one coupon per purchase specified. Any other use constitutes fraud. Void if copied, transferred or expired. CONSUMER: Limit one coupon per purchase specified. Any other use constitutes fraud. Void if copied, transferred or expired. CONSUMER: Limit one coupon per purchase specified. Any other use constitutes fraud. Void if copied, transferred or expired. CONSUMER: Limit one coupon per purchase specified. Any other use constitutes fraud. Void if copied, transferred or expired. TM RETAILER: We will pay you for the face value of this coupon, plus 8¢ handling, if submitted in compliance with the Warner-Lambert RETAILER: We will pay you for the face value of this coupon, plus 8¢ handling, if submitted in compliance with the Warner-Lambert RETAILER: We will pay you for the face value of this coupon, plus 8¢ handling, if submitted in compliance with the Warner-Lambert RETAILER: We will pay you for the face value of this coupon, plus 8¢ handling, if submitted in compliance with the Warner-Lambert
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