TEA Model 510 Nitrogen Analyzer
The model 510 Analyzer provides, fast, accurate, specifi c analysis and detection of thermally
labile nitro compounds found in explosives, and environmental and biological samples Explosives Analysis Comes of Age Fast Results Superiority of Analysis
specifi c instrument for the detection and quantitation of thermally labile
and explosives. It is a fast, sensitive,
analysis - including HPLC analysis using
such conventional detectors as UV or RI. High Specifi city
of all components in the mixture. This is frequently diffi cult because of the
With its high specifi city for the nitrosyl
presence of stabilizers and plasticizers
levels of explosives may be found - such as in wastewater or post blast residues
Unsurpassed Accuracy Post-blast debris analyses - identifi es
presence of plasticizers, stabilizers, and
Quality control - monitors quality of
Environmental analyses - provides
operations or found in body fl uids - can
Thus, the TEA analyzer provides an ideal approach to explosives analysis. It permits:
detection even in the presence of stabilizers or plasticizers
Applications 1) HPLC-TEA Explosives Analysis
20µl injection of a 5 µg/ml solution of a
2) HPLC-TEA Anti-Anginal Pharmaceutical Analysis
20µl injection of a 10 µg/ml solution.
3A and 3B) GC - TEA Selectivity: Nitrosamine/Nitro Compound Analysis
GC-TEA Selectivity: Nitrosamine/Nitro Compound Analysis
pyrolyzer. Since nitrosamines cleave in the 350-550˚C temperature range, it is
the amount of nitrosamines. However, only N-nitroso compounds are detected
when the pyrolyzer temperature is set at 500˚C (3A). When the pyrolyzer
nitro compounds are easily detectable (3B). 4) HPLC-TEA Dynamite Analysis
Sample Mixture of a 60% Giant gelatine dynamite. 20µl injection of a 5 µg/ml
5) HPLC Analysis of Letter Bomb Residue
20µl injection of a 3µg/ml solution of a
Principle of Operation Specifi cation Model TEA 510 Analyzer
ruptures compounds containing nitro groups to release the NO•
Compounds analyzed include, (but are not limited to) the following:
Tetryl - N-methyl-N-2,4,6-tetranitroaniline
and fragmentation products are removed by a cold trap. The nitrosyl radicals continue on into
Confi gurations: The TEA Model 510 Analyzer may be used:
an evacuated reaction chamber where they are oxidized with ozone
By itself, accepting direct injection of samples
In combination with high-performance liquid chromatography
giving off a burst of infrared light. The intensity of the infrared is
Selectivity: The system’s high selectivity arises from its null response to many com-
pounds which usually interfere with explosives analysis. In the GC and LC modes,
compounds are further distinguished by their retention times. The selectivity ratio
for EGDN to alcohols, aromatics, plasticizers, and stabilizers is greater than 107 to 1. Output: Twelve attenuation ranges (1, 2, 4 . . . 1024, 2048)
Reproducibility: Limited by the precision of the chromatographic system used.
Dec. 20, 2002 THE FOOD & DRUG LETTER Issue No. 666 Dec. 20, 2002 CLARITIN APPROVAL MARKS SIGNIFICANT SHIFT IN RX-TO-OTC SWITCHES The switch of Schering-Plough’s Claritin to over-the-counter (OTC) status set new precedents whoseimplications will reach far beyond drugstore shelves and affect the pharmaceutical industry for years. FDA’s Nov. 27 approval of OTC Claritin, the
Redlands USD The following outline of your group’s outpatient prescription drug benefit is provided for your information. This document contains specific coverage and exclusion information related to your prescription benefit provided by Redlands USD and administered by Express Scripts, Inc. For more information about these drugs or others, you can reach us by calling 1-877-586-3115 or by