Mais la polymyxine n'est pas du tout absorbée dans le sang du système gastro-intestinal et n'a d'effet que dans l'intestin et est utile pour le traitement des infections intestinales metronidazole prix Internet en y faisant des achats permettant d’économiser jusqu'à soixante-dix pour cent, tout en étant sûr de la qualité des produits pharmaceutiques.

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Ph.D., Statistics, 1992Colorado State University, Fort Collins, Colorado • Doctoral Dissertation: Estimation for Nearest 1-Neighbor Processes B.S., Mathematics, 1987University of Dayton, Dayton, Ohio • magna cum laude, University Honors Program, biology minor • Undergraduate Honors Thesis: The Development of a Transform Method for Use in Solving Difference Associate Director, then Director, then Senior Director — StatisticsBioMimetic Therapeutics, Inc., 2008 – present Adjunct Associate ProfessorVanderbilt University School of Medicine, Department of Biostatistics, 2008 – present Research Associate ProfessorVanderbilt University School of Medicine, Department of Biostatistics, 2005 – 2008 Principal Consultant Data MiningGlaxoSmithKline, 2001 – 2005 Senior Statistician I, then Senior Statistician II, then Principal StatisticianGlaxo Wellcome, Inc., 1996 – 2001 Senior Statistician, then Statistical ScientistMarion Merrell Dow, Inc. (Hoechst Marion Roussel), 1992 – 1996 Graduate Student Statistics Instructor and ConsultantColorado State University, 1987 – 1992 Undergraduate Mathematics Teaching AssistantUniversity of Dayton, 1985 – 1987 Research AssistantUniversity of Dayton Research Institute, 1985 – 1986 Selected Talks, Presentations, Posters, Abstracts, Classes, and such things On Permissible Correlations for a Class of Stationary Spatial Processes — presented at theKansas–Western Missouri Chapter of the American Statistical Association Summer Meeting, July 1993.
Standardizing Clinical Study Designs for Accelerating Drug Development (with S.J. Ruberg)— presented at the 32nd Annual Meeting of the Drug Information Association as part of the StatisticalTrack: Statistical Strategies for Accelerating Clinical Development, June 1996.
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Adjunctive Lamictal (LTG) Treatment Is Associated With Stable Body Weight in PatientsWith Epilepsy (with J.A. Messenheimer, P.A. Burns, G.D. Rudd, and M.E. Risner) — presented atAmerican Epilepsy Society Meeting, December 1996.
Adult Patients with Epilepsy Maintain Stable Weight During Lamotrigine Therapy: AReview of Data From 30 Clinical Trials (with O. Devinsky, J. Gallagher, and B. Clements) —presented at American Academy of Neurology Meeting, April 1997.
Clinician and Caregiver Assessments of Global Response to Therapy Strongly Agree ina Double-Blind, Placebo-Controlled Trial of Lamotrigine in the Lennox-Gastaut Syndrome(with J. Gallagher, L. Mullens, and G. Rigdon) — presented at American Academy of Neurology Meeting,April 1997.
Evaluation of the Safety and Efficacy of Bupropion SR 150 mg Once Daily and Twice DailyVersus Placebo in Outpatients with Moderate to Severe Depression (with S.R. Batey andJ.A. Ascher) — presented at American College of Neuropsychopharmacology Meeting, December 1997.
Estimating Rankings Under A Stochastic Ordering — presented at Twenty-first Annual MidwestBiopharmaceutical Statistics Workshop, May 1998.
Comparison of the Safety and Efficacy of Bupropion Sustained Release and Paroxetine inElderly Depressed Outpatients (with K. Weihs, E. Settle, T.L. Houser, S.R. Batey, J.A. Ascher, andL.L. Alvarez) — presented at American Psychiatric Association Meeting, June 1998.
Comparison of the Efficacy and Safety Including Sexual Functioning of Bupropion SR andSertraline in Depressed Outpatients (with R. Kavoussi, R.T. Seagraves, S.R. Batey, A. Hughes, andJ.A. Ascher) — presented at American Psychiatric Association Meeting, June 1998.
Clinical Statistics for Non-Statisticians (with C. Chuang-Stein, K. Gordon, M. Mosier, and/orJ. Whitmore) — 1- and 2-day short courses taught in the US and in Europe through the Drug InformationAssociation (approximately 2–3 times annually since June 1998).
Bupropion Sustained Release and Paroxetine Demonstrate Equivalent Quality of Life inElderly Depressed Outpatients (with L. Herrero, Z.M. Khan, S. Batey, and J. Ascher) — presentedat New Clinical Drug Evaluation Unit Program Annual Meeting, June 1998.
Data Issues in International Clinical Trials — invited presentation as part of Regulatory AffairsProfessionals Society conference on International Clinical Trials Today and in the 21st Century, August1998.
Time Course of Effectiveness with Bupropion, Nicotine Replacement, and CombinationTherapy for Smoking Cessation (with B.D. Jamerson, D. Jorenby, J.A. Johnson, M. Fiore, M. Nides,S. Rennard, and S Leischow) — presented at American Society of Addiction Medicine National Conference,November 1998.
A Comparison of the Efficacy and Safety, Including Sexual Functioning, of Bupropion SR,Sertraline, and Placebo in Depressed Outpatients (with J. Ascher, S. Batey, T. Houser, andA. Metz) — presented at American College of Neurophychopharmacology Annual Meeting, December1998.
Pretreatment Anxiety Does Not Predict Response to Bupropion or Sertraline (with J. Rush,T. Carmody, S. Batey, J. Ascher, and V. Lackey) — presented at American Psychiatric AssociationAnnual Meeting, Summer 1999.
Pretreatment Anxiety Does Not Predict Response to Bupropion SR or Sertraline (withJ. Rush, S. Batey, J. Ascher, and T. Carmody ) — presented at New Clinical Drug Evaluation UnitProgram Annual Meeting, June 1999.
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A Darwinian Scheme for Estimating Rankings under a Stochastic Ordering — presented inpart at the Joint Statistical Meetings, Indianapolis, August 2000.
Randomness and Probability for First and Second Graders — presented as part of CatholicSchools Week at The Franciscan School, Raleigh, February 2001.
How Statisticians Think and Why it Matters — invited presentation as part of Drug InformationAssociation Annual Meeting, Denver, July 2001.
Fundamentals of Statistical Thinking — presented as part of the Vanderbilt University MedicalCenter Department of Ophthalmology seminar series, Nashville, July 2001.
Comparing R&D and Commercial: Are All Data Created Equal? — invited presentation as partof the Twenty-fifth Annual Midwest Biopharmaceutical Statistics Workshop, Muncie, Indiana, May 2002.
Statistical Issues in Research Prepartion and Review — two lectures as part of Campbell Univer-sity’s Clinical Research Seminar (CLNR 534), Raleigh, September 2002 and September 2004.
Statistics in Clinical Research: Godsend or Necessary Evil? — invited presentation as part ofRegulatory Affairs Professionals Society Clinical Research Meeting, San Diego, April 2003.
Data Issues in Multinational Trials — invited presentation as part of Regulatory Affairs ProfessionalsSociety Clinical Research Meeting, San Diego, April 2003.
Using Data Mining Techniques to Harvest Information from Clinical Trials (with R. De Veauxand R. Small) — presented by R. De Veaux as part of DIMACS Working Group on Privacy / Confiden-tiality of Health Care Data, Rutgers University, December 2003.
Advanced Clinical Statistics for Non-Statisticians (with C. Chuang-Stein, M. Mosier, and/orJ. Whitmore) — a 2-day short courses taught through the Drug Information Association (approximatelyannually since November 2004).
Statistics as a Career — part of Wakefield Middle School Career Day, Raleigh, March 2005.
Multiple Inferences in Early Phase II Clinical Trials — Performance of Exact Methodsfor Dose Response (with A. Krishen) — presented at the Joint Statistical Meetings, Minneapolis,August 2005.
Fundamental Statistics Concepts in Understanding and Presenting Data — presented at Sec-tion of Surgical Sciences Research Conference (6 January 2006); Department of Anesthesiology Seminar(18 January 2006); General Clinical Research Center Skills Workshop (20 January 2006), Vanderbilt Uni-versity Medical Center, Nashville; Clinical Research Seminar, University of Texas Southwestern MedicalCenter (8 June 2006); Atherogenics, Atlanta (14 June 2006).
Blood Pressure Variability: A Biomarker for Mortality in 1852 Trauma Patients (with H. Cao,P. Norris, N. Mowery, and J. Morris) — abstract in Shock, 25(6) (2006), 54.
(Musings on) the nature of data analysis — Department of Biostatistics Seminar/Workshop Series,Vanderbilt University (11 October 2006); invited presentation at Vanderbilt Kennedy Center for Researchon Human Development seminar (28 April 2007); invited Department of Pathology seminar (14 May 2007);invited monthly MS-level biostatisticians seminar (9 July 2007).
Multiple Lagged Differences in Spatial Times Series (with J. Horner) — presented at the JointStatistical Meetings, Seattle, August 2006.
Data Display Principles Revealed in the NASA Data — presented at the Joint Statistical Meetings,Seattle, August 2006.
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Heart Rate Variability Signals Adrenal Insufficiency in the Critically Ill: A Study of 1871Trauma Patients (with J. Morris, O. Guillamondegui, A. Ozdas, H. Cao, P. Norris, L. Waitman, andJ. Jenkins) — presented at Southern Surgical Association, One Hundred Eighteenth Annual Session,December 2006.
Achieving GBC Reliability — invited presentation at Brickworld, Chicago, June 2007.
Bivariate Baseball Score Plots — presented at the Joint Statistical Meetings, Salt Lake City,July 2007.
How to do a Bayesian Continual Reassessment Method of Assigning Doses to Patients - AGentle introduction by way of example — presented at the Clinical Research Center, VanderbiltUniveristy, November 2007.
Comparisons of the Uses of Logistic and Probit Regression in the Aerospace and BiomedicalFields (with P. Hovey) — presented at the Joint Statistical Meetings, Denver, August 2008.
Fundamental Statistics Concepts in Presenting Data: Principles for Constructing BetterGraphics — presented at the Joint Statistical Meetings, Denver, August 2008, Alexandria, VA April 2009,Vancouver, August 2010, Miami, August 2011, and at Mid-South Compensation Association MonthlyMeeting, September 2012.
University of Dayton Biennial Mathematics Alumni Seminar, Panel Presentation — presentedat the Univeristy of Dayton, 2006, 2012.
On Permissible Correlations for Locally Correlated Stationary Processes (with P. J. Brockwelland R. A. Davis) — Statistics and Probability Letters, 22 (1995), 49–53.
A Summary Statistic for Measuring Change from Baseline — Journal of BiopharmaceuticalStatistics, 7(2) (1997), 287–299.
Standardizing Clinical Study Designs for Accelerating Drug Development (with S.J. Ruberg)— Drug Information Journal, 31 (1997), 655–663.
Costs of Epilepsy in an Intermediate Care Facility for the Mentally Retarded (ICF/MR)(with T.A. Burke, J.R. McKee, D.S. Pathek, T.V. Parasuraman, and A.S. Batenhorst) — The AmericanJournal of Mental Retardation, 104 (1999), 148–157.
A Note on Information Seldom Reported Via the P-value — The American Statistician, 53(1999), 303–306.
Reply to Langbehm’s Comment on A Note on Information Seldom Reported Via the P-value— The American Statistician, 54 (2000), 227–228.
Anxiolysis Associated with Antidepressant Response to bupropion Sustained Release or Ser-traline (with A.J. Rush, M.H. Trivedi, S.R. Batey, T.J. Carmody, T.L. Houser, J.A. Ascher, C. Bolden-Watson, and A. Metz) — International Journal of Neuropsychopharmacology, 3 Supplement 1, (2000),S235.
A Placebo-controlled Comparison of the Antidepressant Efficacy and Effects on Sexual Func-tioning of Sustained-release Bupropion and Sertraline S.R. Batey, and J.A. Ascher) — Clinical Therapeutics, 21 (1999), 643–658.
Sexual Dysfunction Associated with the Treatment of Depression: A Placebo-controlledComparison of Bupropion Sustained Release and Sertraline Treatment (with C.C. Coleman,L.A. Cunningham, V.J. Foster, S.R. Batey, T.L. Houser and J.A. Ascher) — Annals of Clinical Psychiatry,11, (1999), 205–215.
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A Comparison of Time-and-motion and Self-reporting Methods of Work Measurement (withT.A. Burke, J.R. McKee, H.C. Wilson, D.S. Pathek, and A.S. Batenhorst) — Journal of Nursing Admin-istration, 30 (2000), 118–125.
Evaluation of Sexual Functioning in Depressed Outpatients: A Double-Blind Comparisonof Bupropion Sustained Release and Sertraline Treatment (with R.T. Segraves, R. Kavoussi,A.R. Hughes, S.R. Batey, J.A. Johnston, and J.A. Ascher) — The Journal of Clinical Psychopharmacology,20, (2000), 122–128.
Some Commentary on Maximizing the Statistician’s Value to the Pharmaceutical Industry— Drug Information Journal, 34, (2000), 1261–1264.
Bupropion Sustained-Release Versus Paroxetine for the Treatment of Depression in theElderly (with K.L. Weihs, E.C. Settle, S.B. Batey, T.L. Houser, and J.A. Ascher) — The Journal ofClinical Psychiatry, 61, (2000), 196-202.
Improved Health-related Quality of Life and Reduced Productivity Loss after Treat-ment with Wellbutrin SR: A Study in Patients with Major Depression (with D.L. Dunner,W.J. Kwong, T. Houser, N.E. Richard, and Z.M. Khan) — Primary Care Companion to the Journal ofClinical Psychiatry, 3, (2001), 10–16.
Quality of Life in Geriatric Depression: A Comparison of Remitters, Partial Responders,and Nonresponders (with P.M. Doraiswamy, N.E. Richard, and Z.M. Khan) — American Journal ofGeriatric Psychiatry, 9, (2001), 423–428.
The Development of a Darwinian Scheme for Estimating Rankings Under a Stochastic Or-dering — 2000 Proceedings of the Section on Statistics in Sports of the American Statistical Association,(2001), 64–69 (not refereed).
Response in Relation to Baseline Anxiety Levels in Major Depressive Disorder Treatedwith Bupropion Sustained Release or Sertraline (with A.J. Rush, M.H. Trivedi, T. Carmody,T.L. Houser, C. Bolden-Watson, S.R. Batey, J.A. Ascher, and A. Metz) — Neuropsychopharmacology,25, (2001), 131–138.
Does Pretreatment Anxiety Predict Response to Bupropion SR or Sertraline? (with J. Rush,S.Batey, J. Ascher, T. Carmody, and A. Metz) — Journal of Affective Disorders, 64, (2001), 81–87.
Do Bupropion SR and Sertraline Differ in Their Effects on Anxiety in Depressed Patients?(with A.J. Rush, M.H. Trivedi, T. Carmody, T.L. Houser, and C. Bolden-Watson) — Journal of ClinicalPsychiatry, 62, (2001), 776–781.
Late-Term Smoking Cessation Despite Initial Failure: An Evaluation of Bupropion SustainedRelease, Nicotine Patch, Combination Therapy, and Placebo (with B.D. Jamerson, M. Nides,D.E. Jorenby, P. Garrett, J.A. Johnston, M.C. Fiore, S.I. Rennard, and S.J. Leischow) — Clinical Ther-apeutics, 23, (2001), 744–752.
The Spectrum of Quality-of-life Impairments in Recurrent Geriatric Depression (withP.M. Doraiswamy, N.E. Richard, and Z.M. Khan) — Journal of Gerontology Medical Sciences, 57, (2002),M134–M137.
Effect on Body Weight of Bupropion Sustained-Release in Patients with Major DepressionTreated for 52 Weeks (with H. Croft, T.L. Houser, B. Jamerson, R. Leadbetter, C. Bolden-Watson,and A. Metz) — Clinical Therapeutics, 24, (2002), 662–672.
Continuation Phase Treatment with Bupropion SR Effectively Decrease the Risk for Relapseof Depression (with K.L. Weihs, T.L. Houser, S.R. Batey, J.A. Ascher, C. Bolden-Watson, and A. Metz)— Biological Psychiatry, 51, (2002), 753–761.
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Prevalence of Sexual Dysfunction Among Newer Antidepressants (with A. Clayton, J. Pradko,H. Croft, B. Montano, R. Leadbetter, C. Bolden-Watson, K. Bass, B. Jamerson, and A. Metz) — Journalof Clinical Psychiatry, 63, (2002), 357–366.
Statistics in Clinical Research: Godsend or Necessary Evil? — Regulatory Affairs Focus, (De-cember 2003), 37–39 (not refereed).
Cost-effective use of breast biopsy techniques in a Veterans health care system (with A. Hat-maker, J. Tarpley, and A. Pearson) — American Journal of Surgery, 192, (2006), e37–41.
Feeding the Open Abdomen (with B. Collier, O. Guillamondegui, B. Cotton, A. Conrad, K. Groh,J. Richman, T. Vogel, R. Miller, and J. Diaz) — Journal of Parenteral and Enteral Nutrition, 31(5),(2007), 410–415.
Ischemic Complications of Percutaneous Femoral Artery Catheterization (with P.M. Schu-macher, C.B. Ross, Y.-C. Wu, T.J. Ranval, J.B. Dattilo, R.J. Guzman, and T.C. NAslund) — Annals ofVascular Surgery, 21(6), (2007), 704–712.
Autologous Breast Reconstruction: The Vanderbilt Experience (1998 to 2005) of Indepen-dent Predictors of Displeasing Outcomes (with J.A. Greco, E.T. Castaldo, L.B. Nanney, Y.-C. Wu,J.J. Wendel, K.F. Hagan, and R.B. Shack) — Journal of the American College of Surgeons, 207(1),(2008), 49–56.
Tibial Artery Calcification as a Marker of Amputation Risk in Patients with PeripheralArtery Disease (with R.J. Guzman, D.M. Brinkley, P.M. Schumacher, H. Beavers, and X. Qin) —American College of Cardiology, 51(20), (2008), 1967–1974.
Intensive insulin therapy in practice: can we do it? (with L.A. Dossett, B. Collier, N.T. Mowery,M.J. Dortch, O. Guillamondegui, J.J. Diaz, and A.K. May) — Jounral of Parenteral and Enteral Nutrition,33(1), (2009), 14–20.
Insulin Resistance Despite Tight Glucose Control Is Associated With Mortality in CriticallyIll Surgical Patients (with N.T. Mowery, A. Ozdas, M. Dortsch, M.J. Dortch, P.R. Norris, A. Williams,J.A. Morris, and A.K. May) — Critical Care Medicine, 34(12), (2006), 44.
Fundamental Statistical Concepts in Presenting Data; Principles for Constucting BetterGraphics — self-published, 2009.
Multi-institutional experience using human acellular dermal matrix for ventral hernia repairin a compromised surgical field. (with J.J. Diaz, A.M. Conquest, S.J. Ferzoco, D. Vargo, P. Miller,and Y. Wu) — Archives of Surgery, 144(3), (2009), 209–15.
Hepatitis B and hepatitis C in Pakistan: prevalence and risk factors (with S.A. Ali, H. Qureshi,and S.H. Vermund) — International Journal of Infectious Diseases, 13(1), (2008), 9–19.
The impact of reduction mammaplasty on breast sensation: an analysis of multiple surgicaltechniques (with M.E. Spear, L.B. Nanney, S. Phillips, K.M. Rogers, J.J. Wendel, B. Summit, K. Kelly,R.B. Shack, and K.F. Hagan) — Annals of Plastic Surgery, 68(2), (2012), 142–9.
Member of Editorial Board for Drug Information JournalReferee for The American StatisticianMember of the American Statistical AssociationMember of the Drug Information AssociationMember of the National Geographic SocietyDeveloper of Donahue Darwinian Ranking Scheme . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Born 8 January 1965, Milwaukee, WisconsinPrivate pilot’s license, 1989Grand Knight, Knights of Columbus Council #9709, 1999 – 2000Happily married; two wonderful sons, one beautiful daughterBasketball coach, St Francis Youth Basketball League, Raleigh, 1999 – 2005Award for Best GBC Module, Brickfest, August 2005, Washington, D.C.
Basketball coach, Youth Incorporated, Brentwood, 2005–2006Assistant baseball coach, Brentwood Civitan Youth Baseball, Brentwood, 2006Award for Best GBC Module, Brickfest, August 2006, Washington, D.C.
Assistant baseball coach, Brentwood Babe Ruth Baseball, Brentwood, 2006 – 2008Film crew, Ravenwood High School Football team, Brentwood, 2007 – 2011

Source: http://rafe.donahue.home.comcast.net/~rafe.donahue/cv.pdf

Doi:10.1016/j.evolhumbehav.2005.11.002

Evolution and Human Behavior 27 (2006) 259 – 269Male steroid hormones and female preferenceMarkus J. Rantalaa,*,1, C.J. Peter Erikssonb, Anssi Vainikkaa, Raine Korteta,2aDepartment of Biological and Environmental Science, University of Jyva¨skyla¨, P.O. Box 35,bDepartment of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, FinlandInitial receipt 8 September

Mechanism of action

Product Detail Mechanism of action Anqi is an oral antibacterial combination consisting of the semisynthetic antibiotic amoxicillin and the β-lactamase inhibitor, clavulanate potassium (the potassium salt of clavulanic acid). Amoxicillin is an analog of ampicillin. Clavulanic acid is a β-lactam structurally related to the penicillins and possesses the ability to inactivate a wide vari

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