Tadalafil appartiene alla classe degli inibitori selettivi della fosfodiesterasi di tipo 5, con un profilo farmacocinetico caratterizzato da un’emivita terminale di circa diciotto ore. Dopo somministrazione orale viene assorbito rapidamente e raggiunge concentrazioni plasmatiche massime in due ore. La biotrasformazione avviene principalmente tramite CYP3A4 con formazione di metaboliti inattivi, escreti in prevalenza con le feci. L’elevato legame alle proteine plasmatiche (>90%) assicura una distribuzione stabile. Nei confronti delle altre molecole della stessa classe, cialis compresse italia è noto per la durata prolungata dell’attività farmacologica.
Microsoft word - lasse viii programa 23 julho
8th. Latin-American Summer School on Epilepsy - LASSE VIII
“Epilepsy in neurodegenerative diseases and aging”
16-25 February 2014 – São Paulo, Brazil
08:30 – 09:30 – Welcome address and introduction to LASSE
09:30 – 10:30 – Concept of focal and generalized ictogenesis – Peter Wolf (Denmark)
11:00 - 12:00 – Neonatal seizures – Loreto Rios (Chile)
12:00 – 13:00 – Seizures in childhood - Vera Terra (Brazil)
14:00 - 15:00 – Seizures in adults – Elza Marcia Yacubian (Brazil)
15:00 – 16:00 – Seizures in the elderly – Tonicarlo Velasco (Brazil)
16:30 – 18:00 – Overview and discussion – Américo Sakamoto (Brazil)
09:00 – 10:00 – Neuronal death: different paths to the same fate – João Malva
10:00 – 11:00 – Oxidative stress and neuronal cell death – Catarina Oliveira (Portugal)
11:30 – 12:30 – Brain aging and neuroplasticity - Marina Bentivoglio (Italy)
14:00 – 15:00 – Excitotoxicity: glutamate out of the cage – João Malva (Portugal)
15:00 – 16:00 – Neuroinflammation – Joana Palha (Portugal)
16:30 -17:30 – Epilepsy in adult and aged women – Patricia Braga (Uruguay)
16:30 -17:30 - Antiepileptic drug treatment in pregnancy with focus in teratogenicity –
17:30 – 18:30 - Tuberous sclerosis – Sergiusz Jozwiak (Poland)
09:00 – 10:00 – Astrocyte-neuron homeostasis – Rodrigo Cunha (Portugal)
10:00 – 11:00 – Neurogenesis in epilepsy – Helen Scharfman (USA)
11:30 – 12:30 – The neurogenic niche dynamics – João Malva (Portugal)
14:00 – 15:00 – Blood-brain barriers – Joana Palha (Portugal)
15:00 – 16:00 - Caffeine and adenosine receptors in the control of epileptic-like
16:30 – 17:30 – Antiepileptic drugs and SUDEP – Torbjorn Tomson (Sweden)
17:30 – 18:30 – West syndrome – Sergiusz Jozwiak (Poland)
08:30 – 09:30 – Main inborn errors of metabolism – Fernando Kok (Brazil)
09:30 – 10:30 – Investigating genetic syndromes: main aspects – Iscia Lopes Cendes
11:00 – 12:00 – Rett syndrome – Jaime Carrizosa Moog (Colombia)
14:00 – 15:00 – Angelman syndrome – Kette Valente (Brazil)
16:30 – 17:30 – Neuroimaging in brain malformations related to epilepsy – Fernando
17:30 – 18:30 – Seizures in Alzheimer’s disease – Helen Scharfman (USA)
10:00 – 11:00 – Epilepsy and autoimmune encephalitis – Maria Chiara Stefanini (Italy)
11:30 – 12:30 - Continuous spike-wave during sleep – Carlo Alberto Tassinari (Italy)
14:00 – 15:00 – Dravet syndrome – Elza Márcia Yacubian (Brazil)
15:00 – 16:00 – PME – Jesus Machado Salas (México/USA)
16:30 – 17:30 – Focal epilepsies: progressive disorders? Fernando Cendes (Brazil)
17:30 – 18:30 - First Seizure Management - Diagnostic and treatment algorithm in late
onset epilepsies - Bernd Pohlmann-Eden (Canada)
09:00 – 10:00 – Status epilepticus-induced epilepsy: experimental observations – João
10:00 – 11:00 – Classification of status epilepticus – Guilca Contreras (Venezuela)
11:30 – 12:30 - FIREs – Roberto Caraballo (Argentina)
14:00 – 15:00 – Electroencephalographic status epilepticus – Luis Otávio Caboclo
15:00 – 16:00 - Which really matters: the etiology or the spikes? - Alicia Bogacz
16:30 – 17:30 - Does some MTLE represent a progressive degenerative disorder?
09:00 – 10:00 – The Struldbruggs and neurodegeneration – Marina Bentivoglio (Italy)
10:00 – 11:00 – What do we know about the neurobiology of cognitive decline in
normal “aging” and in neurodegenerative diseases? – Giuseppe Bertini (Italy)
11:30 – 12:30 – Cognitive and brain changes in asymptomatic persons at increased risk
for Alzheimer’s disease — Bruce Hermann (USA)
14:00 – 15:00 - Seizures and dementia in Down’s syndrome – Laura Guilhoto (Brazil)
15:00 – 16:00 – Aging in antiquity – Mario Fales (Italy)
08:30 – 09:30 – Translational research: Finding a better drug for epilepsy – Astrid
09:30 – 10:30 - Neuropsychological and brain changes in aging persons with chronic
11:00 – 12:00 – Psychiatric effects of AEDs – Andres Kanner (USA)
14:00 – 15:00 - Acute treatment of epilepsy – Peter Wolf (Denmark)
15:00 – 16:00 – Approach to medically resistant epilepsy - Cigden Ozkara (Turkey)
16:30 – 17:30 – Transcranial magnetic stimulation and medically intractable epilepsies
08:30 – 09:30 – The need for presurgical evaluation – Silvia Kochen (Argentina)
09:30-10:30 - Epilepsy surgery and presurgical evaluation - Cigden Ozkara (Turkey)
11:00 - 12:00 – Surgery in tuberous sclerosis complex – Hélio Rubens Machado (Brazil)
12:00 – 13:00 – Surgery in focal cortical dysplasia – Manuel Campos (Chile)
14:00 – 15:00 – Surgery in PWE older than 50 years – Mario Alonso (Mexico)
THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINEVolume 15, Number 5, 2009, pp. 507–511 ª Mary Ann Liebert, Inc. DOI: 10.1089=acm.2008.0501Effect of BEMER Magnetic Field Therapy on the Levelof Fatigue in Patients with Multiple Sclerosis:A Randomized, Double-Blind Controlled TrialJoachim Piatkowski, M.D.,1 Simone Kern, Ph.D.,2 and Tjalf Ziemssen, M.D.2Objectives: Electromagnetic field
The end of river blindness? people are already infected. The vast majorityof cases (99 per cent) occur in Africa withSightsavers distributed the drugs to infectedover 30 endemic countries on the continent. communities by trained village volunteers whoMore than 300,000 people have already gonehand out the treatment locally. Last year thedevelopment charity helped to protect over23 milli