Mais les résultats doivent être attendus longtemps et il n'y a généralement pas de temps metronidazole prix L'autre cas, c'est que l'achat d'un ou d'un autre antibiotique dans une pharmacie classique nécessite des dépenses matérielles considérables et pas toutes les personnes ne peuvent acheter des produits pharmaceutiques aussi coûteux.

Int. J. Agrl.Sc & Vet.Med. 2013
L Ramsingh et al., 2013
ISSN xxxx-xxxx
Vol. 1, No. 1, February 2013
2013 All Rights Reserved
Research Paper
L Ramsingh1*, K Sadasiva Rao1 and K Muralimohan1
*Corresponding Author: L Ramsingh, Email: [email protected]
In this study, 46 bovines 37 buffaloes, 9 cows were noted with history of cycling normally withoutany clinical abnormalities and returned to estrus even after three or more consecutiveinsemination. The animals were treated with Ciprofloxacin and Tinidazole combination afterconfirming as repeat breeders based on consistency and pH of vaginal discharges. The animalswere inseminated on subsequent estrous. The conception rates were 71.2% and 85.2%respectively for buffaloes and cows.
Keywords: Repeat breeders, Uterine infection, Ciprofloxacin, Tinidazole
endometritis 12.5% subclinical endometritis is a Repeat breeders are animal cycling normally major to the repeat beeder syndrome of bovines without any clinical abnormalities, but fail to (Noakes et al., 2001) and it is major economic conceive even after at least two successive loss in dairy farms. Uterine infection with a varity inseminations. They have clinically normal of antiseptic and antibiotic solutions have been reproductive tract estrous cycles and estrous tried (Oxender and Seguin, 1976). The present periods (Roberts, 1971). The incidence of repeat study was carried to evaluate the efficacy of breeding has 5-32% in cows 6-30% in buffaloes ciprofloxacin and Tinidazole I/U infusion to repeat (Gupta et al., 2005). Uterine infections are the major cause leading to reduced reproductive MATERIALS AND METHODS
efficiency, increase in inter calving period andreduce in calf crop. Sagartz and Hardenbrook The study was conducted in a teaching veterinary (1971) reported endometritis in 77% infertile cows.
clinical hospital college of veterinary science, In another study Hartigan et al. (1972), it was Rajendra Nagar, Hyderaabd, Andhra Pradesh, observed that 50% of genital tract obtained from India during the period of 2011-2012 year. Total an abattoir showed histilogical evidence of 46, 37 buffaloes, 9 cows. These animals were Department of Veterinary Gynaecology & Obstetrics, College of Veterinary Science, Sri Venkateswara Veterinary University,Rajendra Nagar, Hyderabad 500030, Andhra Pradesh, India.
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Int. J. Agrl.Sc & Vet.Med. 2013
L Ramsingh et al., 2013
classified as repat breeders based on cycling 1986; and Sheldon et al., 2008). However during normally without any clinical abnormalities and infection bacterial toxin binds directly to uterine repeated heat after three or more consecutive epithelial and stromal cell to stimulate the release services. The animals had history of normal estrus of prostaglandins E which is luteotropic and may cycles with turbid and thick vaginal discharge at prevent luteolysis (Bogan et al., 2008). After the time of estrus. Vaginal discharge in buffaloes treatment with Ciprofloxacon and Tinidazloe was examined and in case, if it was absent, then combination, vaginal discharges was observed clear and transparent at next estrus. pH of (7.0- stimulate the discharge vaginal discharge and PH 7.2) similar findings was also reported by (Singh before the treatment and after treatment at et al., 2009) per rectal examination after 2-3 subsequent estrus.repeat breeder bovines were months revealed that out of 46 animals 36 have treated with Ciprofloxacin and Tinidazloe conceived (82.2%). Among the bovines, higher combination @60 ml I/U at alternate day for three conception rate was observed in cows (85.2%) than buffalos (71.2%). Conception rate was alsohigher in naturally bred animals 82.2% than RESULTS AND DISCUSSION
artificial inseminated (71.6%). These results are Vaginal discharge observed in all animals of close agreements with the observations of Dash present study were turbid, thick and mucopurulent et al. (2004) and Pandve et al. (2005) as they discharges due to uterine and cervical infection have reported 80% and 82.5% conception rate (Saini et al., 1995; and Single et al., 2004). Uterine and cervical infection suggests that duringparturition, the physical barrier of the cervix, vagina REFERENCES
and vulva are compromised, normally these infections are cured naturally by rapid involution of the uterus, discharges of the uterine contents “Prostaglandin Synthesis, Metabolism, and and mobilization of the host defense including Singanling Potential in the Rhesus Macaque mucus, antibodies and phagocytes. Periparturient Cropus Luteum Throughout the Luteal Phase complication like retained placenta, dystocia, of the Menstrual Cycle”, Endocrinology, twins, dead foetus, milk fever, etc., increases the risk of uterine infection because they delay 2. Das K K (2004), “A Trial on the Commonly involution and reduces the bovine ability to control uterine infections. Rearing in unhygienic condition Controlling of Repeat Breeding Condition in and insemination in non sterile condition also Cattle Intas Polivet”, Vol. 5, pp.199-203.
cause uterine infection. Increases of pH 7.5-8.0of vaginal discharges was in agreement with previous studies in cattle with endometritis (Saini “Microbial Study of Gynaecologyical Infection et al.,1995; and Single et al., 2004). This could in Cattle”, Indian Journal of Animal be due to bacterial contamination of uterine fluids Reproduction, Vol. 14, pp. 118-119.
and the increased pH is not suitable for survival 4. Hartigan P J, Murphy J A, Nunn W R and of spermatozoa and embryo in the uterus (Robert, Griffin J F T (1972), “An Investigation in to This article can be downloaded from
Int. J. Agrl.Sc & Vet.Med. 2013
L Ramsingh et al., 2013
the Causes of Reproductive Failure in Dairy 11. Saini P S, Grewal A S, Nanda A S and Arora A K (1995), “Intra-Uterine Immunotherapy Normal Repeat Breeder Cow”, Irish Vet. J., Associated with Clinical Cases of RepeatBreeders in Dairy Cattle (Bos Taurus X Bos Indicus) and Buffaloes (Bubalis Bubalis)”, G C W (2001), Arthur ’s Veterinary Bull. Soc. France Japanese Sci. Vet., Obstetrics, 8th Edition, W B Saundaer 12. Sheldon I M, Lewis G S, Le Blanc S and Gilbert R O (2006), “Defining Post-Partum “Bovine Intrauterine Theraphy”, Journal Uterine Diseases in Cattle”, Theriogenolgy, Animal Veterinary Medicine Assocation, 13. Singh A K, Akthar H, Singh R B, Singh A P, Rey G P and Verma S B (2001), “Efficacy of (2005), “Intrauterine Use of Ciprofloxacin in the Treatment of Infectious Repeat Breeding Crossed Cows: A Field Study”, Intas Polivet, Buffaloes”, Indian Journal of Animal Reproduction, Vol. 22, pp. 57-59.
8. Roberts S J (1971), Veterinary Obstetrics 14. Singh Jagir, Ghuman S P S, Dadarwal D, Published by the Author, pp, 496-506, Ithaca, 9. Robert S J (1986), Veterinary Obstetrics and Buffaloes”, Intas Polivet, Vol. 10, pp. 25-28.
Genital Diseases, 3rd Edition, S J Roberts 15. Singla P, Singh Jagir, Sharma N S, Dhaliwal Woodstock (Ed.), pp. 359-381, New York.
G S and Kumar Ajeet (2004), “Effect of Post 10. Sagartz J W and Hardenook H J (1971), “A A.I. Immunotherapy on Dynamics of Uterine Clinical Bacteriologic and Histologic Survey of Infertile Cow”, J. Am. Vet. Med. Assoc., Endometritis Cows”, Indian Journal Animal Sciences, Vol. 74, pp. 706-770.
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