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If you suffer from knee pain, it’s possible you have arthritis. Arthritis in the knee is caused by the deterioration of cartilage in the knee joint. The two most common types of arthritis in the knee are osteoarthritis and rheumatoid arthritis. Osteoarthritis is a progressive, degenerative disease in which the cartilage of the knee slowly wears away. Cartilage serves as insulation between the bones of the joint, and when the cartilage of the knee joint wears away due to osteoarthritis, the resulting pain and inflammation can be debilitating. Your chances of osteoarthritis of the knee increase with age; the illness most often affects middle-aged and older people. Osteoarthritis may first appear between the ages of 30 and 40, though symptoms may not be present in the early stages. By the age of 70 almost everyone will have osteoarthritis of the knee. The question of what causes osteoarthritis of the knee has not been answered. Prior knee injuries seem to increase the likelihood of osteoarthritis, but many people with arthritis of the knee have never had a serious knee injury. Osteoarthritis is the most common form of arthritis, and many people have a genetic predisposition to this chronic disease. The primary symptoms of osteoarthritis are pain in the knee, swelling and stiffening of the knee joint. In the early stages of osteoarthritis the pain may be mainly associated with activity. As the cartilage wears away and the bones of the joint rub against each other, pain can become more severe and constant, interfering with regular daily activities and disrupting sleep. In the early stages of osteoarthritis, treatment may involve several techniques. Behavioral and lifestyle changes including losing weight and changing routines to avoid painful situations can be very effective in relieving pain. Non-steroidal anti-inflammatory drugs (NSAIDs) such as naproxen sodium may also provide relief from pain. Cox-2 inhibitors are also effective in providing arthritis pain relief. Physical therapy may improve muscle strength and joint mobility, reducing the symptoms of osteoarthritis in the knee. Joint fluid therapy such as Supartz. brand hyalauronic acid ( may lubricate the knee and reduce the pain and swelling of the joint. Partial or total knee replacement surgery may be necessary as the disease progresses and daily functioning becomes more impaired. Unlike osteoarthritis, Rheumatoid arthritis involves inflammation of the lining of the joints, known as the synovium. Though less common than osteoarthritis, rheumatoid arthritis is among the most debilitating of the over one hundred forms of arthritis. Rheumatoid arthritis usually develops in middle age, but may occur in the 20s and 30s. The exact cause of rheumatoid arthritis is unknown. It’s possible that a virus or bacteria may trigger the disease in people with a genetic predisposition to rheumatoid arthritis. Many doctors think rheumatoid arthritis is an autoimmune disease in which the tissue of the joint’s lining is attacked by the body’s immune system. It’s also possible that rheumatoid arthritis is caused by severe stress. The disease sometimes occurs after a life-changing event such as divorce, loss of a job or a severe injury. The primary symptoms of rheumatoid arthritis include pain and swelling in the joints and difficulty moving. Other symptoms may include loss of appetite, fever, loss of energy, anemia, and rheumatoid nodules (lumps of tissue under the skin). Treatment of rheumatoid arthritis usually involves medications such as NSAIDs, aspirin and analgesics. In severe cases, surgery may be indicated to replace the knee joint with an artificial joint. If you think you may have arthritis of the knee, contact your doctor for a complete evaluation and a discussion of the options available for treatment. .



Age and Ageing Advance Access published February 24, 2013 © The Author 2013. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: [email protected] risk of hip fracture among olderpeople using antidepressant drugs: datafrom the Norwegian Prescription Databaseand the Norwegian Hip Fracture Reg

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