Fiche de pr_sentation individuelle

Present address UPCM CR7 Université Pierre et Marie Curie, INSERM U1135, CNRS ERL 8255,
Pitié-Salpêtrière, 91 Bd de l’Hôpital, 75013 Paris, France.
Tel: +33 6 85 31 06 49 e-ma
Positions since 2000

Senior Researcher, then DR2 CNRS (URA 2581), in the laboratory of Dr. Pierre Druilhe, Unité de Parasitologie Biomédicale, Institut Pasteur, 25 Rue Du Dr. Roux, 75724 Paris Cedex 15, France.
Head of USM0307 (IFR101), Unité de Parasitologie Comparée et Modèles Expérimentaux, Muséum National d'Histoire, CP52, 61 Rue Buffon, 75231 Paris Cedex 5, France.
Senior Scientist at the UPMC/INSERM UMR S 945 (previously UMR S 911) “Immuno-Biologie Cellulaire et Moléculaire des Infections Parasitaires”, Université Pierre et Marie Curie (Paris VI), Centre Hospitalo-Universitaire Pitié-Salpêtrière, 91 Boulevard de l’Hôpital-75643 Paris Cedex 13, France. (2008-2011) Visiting Senior Research Fellow, Laboratory of Molecular and Cellular Parasitology,
Department of Microbiology, National University of Singapore, Singapore.
(2008-2011) Visiting Senior Researcher, Laboratory of Malaria Immunobiology, Singapore
Immunology Network, A*STAR - Biopolis, Singapore.
2014- Co-Head of the CIMI’s Team 6 “Malaria: identification and pre-clinical validation of novel
therapeutics”UPCM CR7 Université Pierre et Marie Curie, INSERM U1135, CNRS ERL 8255, Pitié-Salpêtrière, 91 Bd de l’Hôpital, 75013 Paris, France. Selected Publications (past 10 years) H factor: 41
1. Belnoue E, Costa FTM, Frankenberg T, Vigário AM, Voza T, Leroy N, Rodrigues MM, Landau I, Snounou G, & Rénia L (2004) Protective T cell immunity against malaria liver stage after
vaccination with live sporozoites under chloroquine treatment. Journal of Immunology 172, 2487-
2. Imwong M, Pukrittayakamee S, Grüner AC, Rénia L, Letourneur F, Looareesuwan S, White NJ, & Snounou G (2005) Practical PCR genotyping protocols for Plasmodium vivax using Pvcs and
Pvmsp1. Malaria Journal 4, 20.
3. Grüner AC, Hez-Deroubaix S, Snounou G, Hall N, Bouchier C, Letourneur F, Landau I, & Druilhe
P (2005) Insights into the P. y. yoelii hepatic stage transcriptome reveal complex transcriptional
patterns. Molecular and Biochemical Parasitology 142, 184-192.
4. Voza T, Vigário AM, Belnoue E, Grüner AC, Deschemin J-C, Kayibanda M, Delmas F, Janse CJ, Franke-Fayard B, Waters AP, Landau I, Snounou G, & Rénia L (2005) Species-specific inhibition
of cerebral malaria in mice coinfected with Plasmodium spp. Infection and Immunity 73, 4777-
5. Carraz M, Jossang, A, Franetich, JF, Siau A, Ciceron L. Hannoun L, Sauerwein R, Frappier F, Rasoanaivo P, Snounou G & Mazier D (2006) A plant-derived morphinan as a novel lead
compound active against malaria liver stages. PLoS Medicine 3, e513.
6. Imwong M, Snounou G, Pukrittayakamee S, Tanomsing N, Kim JR, Nandy A, Guthmann JP,
Nosten F, Carlton J, Looareesuwan S, Nair S, Sudimack D, Day NP, Anderson TJ & White NJ (2007) Relapses of Plasmodium vivax infection usually result from activation of heterologous
hypnozoites. Journal of Infectious Diseases 7, 927-933.
7. Yamauchi LM, Coppi A, Snounou G & Sinnis P (2007) Plasmodium sporozoites trickle out of the
injection site. Cellular Microbiology 9, 1215-1222.
8. Grüner AC, Mauduit M, Tewari R, Romero JF, Depinay N, Kayibanda M, Lallemand E, Chavatte JC, Crisanti A, Sinnis P, Mazier D, Corradin G, Snounou G & Rénia L (2007) Sterile protection
against malaria is independent of immune responses to the circumsporozoite protein. PLoS ONE 2,
9. Roestenberg M, McCall M, Hopman J, Wiersma J, Luty AJF, Van Gemert G-J, Van de Vegte- Bolmer M, Van Schaijk B, Teelen K, Arens T, Spaarman L, De Mast Q, Roeffen W, Snounou G,
Rénia L, Van der Ven A, Hermsen CC & Sauerwein R (2009) Protection against a malaria
challenge by sporozoite inoculation. New England Journal of Medicine 361, 468-477.
10. Mazier D, Rénia L & Snounou G (2009) A pre-emptive strike against malaria's stealthy hepatic
forms. Nature Reviews. Drug Discovery 8, 854-64.
11. Krief S, Escalante AA, Pacheco MA, Mugisha L, André C, Halbwax M, Fischer A, Krief J-M, Kasenene JM, Crandfield M, Cornejo OE, Chavatte J-M, Lin C, Letourneur F, Grüner AC,
McCutchan TF, Rénia L & Snounou G (2010) On the diversity of malaria parasites in African apes
and the origin of Plasmodium falciparum from bonobos. PLoS Pathogens 6, e1000765.
12. Sutherland CJ, Tanomsing N, Nolder D, Oguike M, Jennison C, Pukrittayakamee S, Dolecek C, Tran Tinh Hien, Do Rosário VE, Arez AP, Pinto J, Michon P, Escalante AA, Nosten F, Burke M,
Lee R, Blaze M, Otto TD, Barnwell JW, Pain A, Williams J, White NJ, Day NPJ, Snounou G,
Lockhart PJ, Chiodini PL, Imwong M & Polley SD (2010) Two nonrecombining sympatric forms
of the human malaria parasite Plasmodium ovale occur globally. Journal of Infectious Diseases
201, 1544-1550.
13. Carvalho BO, Lopes SCP, Nogueira PA, Orlandi PP, Bargieri DY, Blanco YC, Mamoni R, Leite JA, Rodrigues MM, Soares IS, Oliveira TR, Wunderlich G, Lacerda MVG, Del Portillo HA,
Araújo MOG, Russell B, Suwanarusk R, Snounou G, Rénia L & Costa FTM (2010) On the
cytoadhesion of Plasmodium vivax-infected erythrocytes. Journal of Infectious Diseases 202, 638-
14. Dembélé L, Gego A, Zeeman A-M, Franetich J-F, Silvie O, Rametti A, Le Grand R, Dereuddre- Bosquet N, Sauerwein R, van Gemert G-J, Vaillant J-C, Thomas AW, Snounou G, Kocken CHM
& Mazier D (2011) Towards an in vitro model of Plasmodium hypnozoites suitable for drug
discovery. PLoS ONE 6, e18162.
15. Russell B, Suwanarusk R, Borlon C, Costa FTM, Chu CS, Rijken MJ, Sriprawat K, Warter L, Koh EGL, Malleret B, Colin Y, Bertrand O, Adams JH, D'Alessandro U, Snounou G, Nosten F &
Rénia L (2011) A reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax.
Blood 118, e74-e81.
16. Obeid M, Franetich J-F, Lorthiois A, Gego A, Grüner AC, Tefit M, Boucheix C, Snounou G &
Mazier D (2013) Skin-draining lymph node priming is sufficient to induce sterile immunity against
pre-erythrocytic malaria. EMBO Molecular Medicine 5, 250-263.
17. Snounou G & Pérignon J-L (2013) Malariotherapy - Insanity at the service of malariology.
Advances in Parasitology 81, 223-255.
18. Dembélé L, Franetich JF, Lorthiois A, Gego A, Zeeman AM, Kocken CH, Le Grand R, Dereuddre- Bosquet N, Sauerwein R, van Gemert GJ, Vaillant JC, Hannoun L, Fuchter MJ, Malmquist NA,
Scherf A, Snounou G, Mazier D. (2014) Persistence and activation of malaria hypnozoites in long-
term primary hepatocyte cultures. Nature Medicine 2014, Feb 9.


General Summary This guide instructs the methods, reaction principles and points for attention for the use of Uritest Reagent Strips. Uritest Reagent Strips are made for urinalysis of both qualitative and semi-quantitative, which are in vitro reagent for diagnostics. The strips are for professional use only. Reagent Strips are the primary testing product for the diseases of abnormal kidney

Cond 1.184

D: SGA: birth weight < 20th percentile for gestational age or < 2.5 kg. LGA: birth weight > 90th percentile for gestational age or > 4 kg. A: SGA: may be familial, constitutional, or due to IUGR. IUGR is defined as either symmetrical or asymmetrical:Asymmetrical IUGR: relative sparing of head circumference in relation toweight and length:. Due to impaired uteroplacental function 28

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