Tadalafil appartiene alla classe degli inibitori selettivi della fosfodiesterasi di tipo 5, con un profilo farmacocinetico caratterizzato da un’emivita terminale di circa diciotto ore. Dopo somministrazione orale viene assorbito rapidamente e raggiunge concentrazioni plasmatiche massime in due ore. La biotrasformazione avviene principalmente tramite CYP3A4 con formazione di metaboliti inattivi, escreti in prevalenza con le feci. L’elevato legame alle proteine plasmatiche (>90%) assicura una distribuzione stabile. Nei confronti delle altre molecole della stessa classe, cialis compresse italia è noto per la durata prolungata dell’attività farmacologica.

Cbio.ufs.ac.za

Pharmaceutical
2-Hydroxyethylflurazepam 3,4-Methylenedioxyamphetamine 3,4-Methylenedioxymethamphetamine 6-O-Monoacetylmorphine 7-Aminoclonazepam 7-Aminoflunitrazepam 7-Aminonitrazepam 9-Hydroxyrisperidone Aceclidine Aceprometazine Aciclovir Ajmaline Alprazolam Alprenolol Amantadine Amiloride Aminophenazone Aminopromazine Amiodarone Amiphenazole Amitriptylin Amoxicillin Amphetamine Apomorphine Aprinidine Atenolol Atorvastatin Atropine Aztreonam Befunolol Bendiacarb Benzatropine Benzocaine Benzoctamine Benzoylecgonine Berberine Betaxolol Bezafibrate Biperiden Bisoprolol Bromazepam Bromocriptine Brompheniramine Bucetin Bunitrolol Bupivacaine Bupranolol Buprenorphine Buspirone Butaperazine Caffeine Carazolol Carbamazepine Carbinoxamine Carbuterol Carteolol Carvedilol Celiprolol Cetirizine Chlorcyclizine Chlordiazepoxide Chlorphenethiazine Chlorpheniramine Chlorpromazine Chlorprothixene Cilazapril Cinnarizine Citalopram Clemastine Clenbuterol Clobazam Clobutinol Clomethiazole Copyright 2010 University of the Free State Clomipramine Clonazepam Clonidine Clozapine Cocaine Codeine Coumatetralyl Cyclicine Desalkylflurazepam Desipramine Desmethylclomipramine Dextromethorphan Dextropropoxyphene Diazepam Dihydrocodeine Dihydroergotamine Dilazep Diltiazem Diphenhydramine Dipyridamole Disopyramide Dixyrazine Doxapram Doxepin Ecgoninemethylester Embutramide Enalapril Ephedrine Eprosartan Esmolol Estazolam Ethenzamide Felodipine Fenarimol Fendiline Fenetylline Fenfluramine Fentanyl Fexofenadine Flecainide Fluconazole Flunitrazepam Fluoxetine Fluphenazine Flurazepam Fluvoxamine Gabapentin Gallopamil Glibenclamide Glibornuride Glimepiride Glipizide Gliquidone Haloperidol Heroin Hydrocodone Hydrocortisone Hydromorphone α-Hydroxyalprazolam α-Hydroxytriazolam Hydroxyzine Imipramine Indomethacin Indoprofen Irbesartan Ketamine Ketoprofen Ketorolac Lamotrigine Lercanidipine Levocabastine Levomepromazine Lidocaine Lisinopril Loperamide Loratadine Lorazepam Lormetazepam Losartan Copyright 2010 University of the Free State Lysergide Maprotiline Meclizine Medazepam Meloxicam Melperone Mepindolol Mescaline Mesoridazine Metaclazepam Metamfepramone Metamphetamine Metformin Methadone Methylphenidate Metipranolol Metoprolol Metronidazole Mexiletine Mianserin Miconazole Midazolam Midodrine Minoxidil Mirtazapine Mizolastine Moclobemide Morphine Morphine-3-O-D-glucuronide Naloxone Nandrolone Nicardipine Nicotine Nifedipine Nifenazone Nimodipine Nisoldipine Nitrazepam Nitrendipine Norbuprenorphine Nordiazepam Norfenefrine Norfentanyl Normorphine Nortriptyline Noscapine Olanzapine Ondansetron Orphenadrine Oxazepam Oxcarbazepine Oxetacaine Oxitropium Oxprenolol Oxycodone Papaverine Paracetamol Paroxetine Pentoxyverine Perazine Perphenazine Phenazone Phencyclidine Pheniramine Phenylephrine Phenyltoloxamine Physostigmine Pilocarpine Pindolol Pioglitazone Pirbuterol Pirenzepine Piroxicam Prajmalium Prazepam Prazosin Primidone Procainamide Progesterone Copyright 2010 University of the Free State Promazine Propafenone Propionylpromazine Propranolol Propyphenazone Prothiopendyl Protriptyline Pseudoephedrine Quetiapine Quinapril Quinine Ramipril Ranitidine Repaglinide Risperidone Ritodrine Ropivacaine Rosiglitazon Scopolamine Serotonin Sertindole Sertraline Sildenafil Sotalol Sulindac Sulpiride Talinolol Tamoxifen Telmisartan Temazepam Terfenadine Tetracaine Tetrazepam Tetryzoline THC THC-COOH THC-OH Theobromine Theophylline Thioridazine Tilidine Timolol Tizanidine Tocainide Tolbutamide Toliprolol Tramadol Trazodone Triamterene Triazolam Trifluperazine Trifluperidol Trimethoprim Trimipramine Urapidil Valsartan Vardenafil Venlafaxine Verapamil Vincamine Warfarin Yohimbine Zolpidem Zopiclone Zuclopenthixol Copyright 2010 University of the Free State

Source: http://cbio.ufs.ac.za/liquidtech/Download/analysis_qualitative_positive_pharmaceuticals_all.pdf