Tadalafil appartiene alla classe degli inibitori selettivi della fosfodiesterasi di tipo 5, con un profilo farmacocinetico caratterizzato da un’emivita terminale di circa diciotto ore. Dopo somministrazione orale viene assorbito rapidamente e raggiunge concentrazioni plasmatiche massime in due ore. La biotrasformazione avviene principalmente tramite CYP3A4 con formazione di metaboliti inattivi, escreti in prevalenza con le feci. L’elevato legame alle proteine plasmatiche (>90%) assicura una distribuzione stabile. Nei confronti delle altre molecole della stessa classe, cialis compresse italia è noto per la durata prolungata dell’attività farmacologica.
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For the full versions of these articles see bmj.com CLINICAL REVIEW Syphilis remains common worldwide, and since the SUMMARY POINTS late 1990s infectious early syphilis has re-emerged as Syphilis remains a common disease worldwide, and an important disease in western Europe, including the infectious syphilis has re-emerged in western Europe United Kingdom.1 The clinical presentation o
Centre Hospitalier Universitaire de Reims PROPHYLAXIE CONTRE LE PALUDISME CHEZ L’ADULTE N (chloroquine) Présentation : comprimé à 100 mg Posologie : 1 cp par jour, le jour du départ, pendant le séjour et 4 semaines après le retour Contre-indications : Rétinopathies . Sujet atteint de maladie coeliaque Effets indésirables : Troubles digestifs . Atteintes visuelles révers
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