Curriculum vitae

CURRICULUM VITAE
Date Completed: June 7, 2011
NAME: Elizabeth Flora JUNIPER
EDUCATIONAL BACKGROUND
a.
Sherborne School for Girls, Dorset, England. l958-l964 l964 - Oxford and Cambridge Certificate of Education St. Thomas' Hospital School of Physiotherapy, London, England. l965-l968 l968 - Member of Chartered Society of Physiotherapists Ewell Technical College, Surrey, England. l970-l972 l972 - Higher National Certificate in Medical Physics and Physiological Measurement McMaster University, Hamilton, Ontario, Canada. l983-1988 1988 - Master of Science in Design, Measurement and Evaluation. (Clinical Epidemiology and Biostatistics)
CURRENT STATUS AT MCMASTER UNIVERSITY, CANADA
Professor Emeritus, Department of Clinical Epidemiology and Biostatistics.
EMPLOYMENT HISTORY
1969-73
Technologist, Respiratory Unit, Royal Postgraduate Medical School, Hammersmith Hospital, London, England. Research Assistant, Cardio-Respiratory Unit, McMaster University Medical Centre, Hamilton, Ontario. Research Associate, Chest and Allergy Unit, St. Joseph's Hospital, McMaster University, Ontario. Lecturer, Department of Medicine, Chest and Allergy Unit, St. Joseph's Hospital, McMaster University, Ontario. Lecturer, Department of Clinical Epidemiology and Biostatistics, McMaster University Medical Centre, McMaster University, Ontario. Assistant Professor, Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario. Associate Clinical Professor, Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario. Professor, Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario. Professor Emeritus, Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario. SCHOLARLY AND PROFESSIONAL ACTIVITIES
1) Publication
Journal Referee:-
Journal of Allergy and Clinical Immunology American College of Physicians Journal Club 2) Committees:- McMaster University 1984-5 Graduate Education Committee, Department of Clinical Epidemiology and Biostatistics Health Sciences Graduate Student Council Faculty of Health Sciences Committee on Graduate Curriculum and Policy. Co-chair. Critical Appraisal Resource Group. Chair. Critical Appraisal Resource Group. Chair. How to Teach Evidence Based-Medicine Workshop International Consensus on Rhinitis Group American Thoracic Society. Behavioral Sciences Section Program Committee Editorial Board for Consensus Conference on Long-Term Implications of Chronic Rhinitis American Thoracic Society. Clinical Practice Committee
HONOURS
1972
Beecham Award for best student in HNC Medical Physics program Roxon Award for best technical paper. Canadian Society of Pulmonary and Cardiovascular Technologists. Roxon Award for best technical paper. Canadian Society of Pulmonary and Cardiovascular Technologists. Roxon Award for best technical paper. Canadian Society of Pulmonary and Cardiovascular Canadian Society for Clinical Investigation - Student Award American Thoracic Society: Year in Review - Asthma. Publication: Juniper EF et al Quality of life in asthma clinical trials: salmeterol vs salbutamol. Am J Respir Crit Care Med 1995; 151: 66-70. Identified 1st in top 5 clinical publications (all journals). Robert J. Becker Lectureship. American Academy of Asthma, Allergy and Immunology. 1997. Therapeutic responses in asthma: measuring quality of life.
EDUCATION
(For more details, see Teaching Dossier)
EVIDENCE-BASED MEDICINE
1990 - 1993
Director of and tutor for the 'How to Teach Critical Appraisal' annual workshop (A one week workshop held annually at McMaster) Director of and tutor for the 'How to Teach Evidence-Based Medicine' workshop (A one week workshop held annually at McMaster) Editor of the Clinical Epidemiology Newsletter Department of Clinical Epidemiology and Biostatistics coordinator for MD electives in Evidence-Based Medicine Tutor for MD electives in Evidence-Based Medicine and Critical Appraisal HEALTH RESEARCH METHODS GRADUATE PROGRAM MSc Student Advisor MSc Thesis Committee Courses Taught MS702, Introduction to Biostatistics, Tutor 1984, 1985, 1986, 1987, 1988, 1989, 1990, 1991 MS721, Fundamentals of Clinical Epidemiology, Tutor 1990, 1991, 1992 (Gp. Leader), 1993 MS730, Introductions to Research Methods in Health Sciences, Tutor 1990, 1991, 1992 (Gp. Leader), 1994, 1995, 1996, 1997, 1998, 1999 MS744, Measurement in Health Research, Co-tutor 1991, Tutor 1992, 1993, 1994, 1995 (Course Director), 1996 (Course Director), 1997 (Course Director), 1998 (Course Director), 1999 (Course Director) M.D. program, Unit 2, Co-tutor 1987, 1988, Tutor 1989. Electives in critical appraisal 1991, 1992, 1993, 1994 Electives in evidence-based medicine 1994, 1995, 1996 Nominated for the Jack Sibley Award for outstanding contribution to education in the Faculty of Health Sciences, McMaster University. PUBLICATIONS
Books
1.
Juniper EF, Cockcroft DW, Hargreave FE. Histamine and methacholine inhalation tests: tidal breathing method. Laboratory procedure and standardisation. 1991, AB Draco, Lund, Sweden. Juniper EF, Cockcroft DW, Hargreave FE. Histamine and methacholine inhalation tests: tidal breathing method. Laboratory procedure and standardisation. 1994, AB Draco, Lund, Sweden (Second Edition) Juniper EF, Fabbri LM, Boner A. Asthma e qualita di vita. 1999,Il Pensiero Scientifico Editore, Roma, Italy. Juniper EF, Lund VJ. Health-related quality of life issues in allergic rhinitis. 2001, UCB Institute of Allergy, Brussels, Belgium.
Book Chapters
1.
Hargreave FE, Juniper EF, Ryan G, Dolovich M, Cartier A, Frith PA, Newhouse MT. Clinical significance of nonspecific airway hyperreactivity. In: Hargreave FE, ed, Airway Reactivity: mechanisms and clinical relevance. Mississauga: Astra Pharmaceuticals Canada Ltd, l980; 2l6-222. Hargreave FE, Frith PA, Dolovich M, Cartier A, Ryan G, Juniper EF, Dolovich J, Newhouse MT. Allergen-induced airway responses and relationships with non-specific reactivity. In: Hargreave FE, ed, Airway Reactivity: mechanisms and clinical relevance. Mississauga: Astra Pharmaceuticals Canada Ltd, l980; 145-150. Juniper EF, Kline PA, Vanzieleghem MA, Hargreave FE. Long-term effects of an inhaled steroid (Budesonide) on airway responsiveness and clinical asthma severity: a double-blind randomised controlled trial. In: Hargreave FE, Hogg JC, Malo JL, Toogood JH. eds, Glucocorticoids and mechanisms of asthma. Exerpta Medica, Amsterdam, 1989; 157-61. Juniper EF, Newhouse MT. Effect of pregnancy on asthma: a critical appraisal of the literature. In: Schatz M, Zeiger RS. eds. Asthma and allergy in pregnancy and early infancy. Marcel Dekker, New York, 1993; 223-249. Juniper EF. Assessment of asthma control: quality of life. In: O'Byrne PM, Thomson N. eds. Manual of asthma management. W.B. Saunders, London, 1995; 176-184. Juniper EF, Guyatt GH, Jaeschke R. How to develop and validate a new quality of life instrument. In: Spilker B. ed. Quality of Life and Pharmacoeconomics in Clinical Trials. Second Edition. Raven Press Ltd, New York, 1995, p 49-56. Juniper EF, Guyatt GH. Asthma and allergy. In: Spilker B. ed. Quality of Life and Pharmacoeconomics in Clinical Trials. Second Edition. Raven Press, New York, 1995, p 977-82. Juniper, EF. Assessment of health-related quality of life in asthma and rhinitis using disease-specific instruments. In: Chanez P, Bousquet J, Michel FB, Godard P. eds. From genetics to quality of life: the optimal treatment and management of asthma. Hogrefe and Huber, Seattle, 1996; p.209-214. Juniper EF. Quality-of-life measures. In: Kotses H, Harver A. Self-management of asthma. Lung Biology in Health and Disease, vol 113. Marcel Dekker, Inc., New York, 1997; p. 91-115. Juniper EF. Health-related quality of life. In: Barnes PJ, Grunstein MM, Leff A, Woolcock AJ. eds. Asthma, Lippincott-Raven Publishers, Philadelphia, PA, USA. 1997; p. 1487-1497. Juniper EF, Newhouse MT. Effect of pregnancy on asthma: a systematic review and meta-analysis. In: Schatz M, Zeiger RS. Claman HN. eds. Asthma and immunological diseases in pregnancy and early infancy. Lung Biology in Health and Disease, vol 110, Marcel Dekker Inc., New York, 1997; p.401-425. Feeny D, Juniper EF, Ferrie PJ, Griffith LE, Guyatt GH. Why not just ask the kids? Health-related quality of life in children with asthma. In: Drotar D (ed). Assessing pediatric health-related quality of life and functional status: implications for research, practice and policy. Lawrence Erlbaum Associates Inc., Mahwah, New Jersey, 1998; p.171-186. Guyatt GH, Juniper EF. Health status instruments, measurement properties of . In: Armitage P, Colton T (eds). Encyclopedia of Biostatistics. Wiley and Sons Ltd., Chichester 1998; p.1890-1895. Juniper EF. Health-related quality of life in rhinitis. In: Mygind N, Naclerio RM, Durham S. Allergic and non-allergic rhinitis: clinical aspects. Lung Biology in Health and Disease. Marcel Dekker, New York, 1999; p. 135-146. Juniper EF. Measuring health-related quality of life for persons with asthma: an overview. In Weiss K, Buist AS, Sullivan SD (eds). Socioeconomic impact of asthma. Lung Biology in Health and Disease. Marcel Dekker Inc. New York, 2000; p. 77-98. Juniper EF. Assessment of asthma control: quality of life. In: O'Byrne PM, Thomson N. eds. Manual of asthma management. Second Edition. WB Saunders, London. 2001; p. 135-142. Thompson AK, Juniper EF, Meltzer EO. Quality of life in patients with allergic rhinitis. In: Kaliner MA. ed. Current reviews of rhinitis. Current Medicine Inc., Philadelphia 2002; p.13-21. Juniper EF. Quality of life. In: Gibson P ed. Monitoring Asthma. Taylor and Francis Group, Baton Rouge, FL, USA 2005; p. 19-40. Juniper EF. Quality of life and treatment of asthma. In: Pauwels R, Advenier C, O'Byrne P. eds. 'Antiasthmatic drugs' in 'Progress in basic and clinical pharmacology' Karger, Basel, Switzerland, (in press). PEER REVIEWED JOURNAL ARTICLES
1.
Spiro SG, Juniper EF, Bowman P, Edwards RHT. An increasing work rate test for assessing the physiological strain of sub-maximal exercise. Clin Sci and Mol Med l974; 46:l9l-206. Rebuck AS, Juniper EF. Effect of resistive loading on ventilatory response to hypoxia. J Appl Physiol l975; 38:965-968. Juniper EF, Frith PA, Dunnett C, Cockcroft DW, Hargreave FE. Reproducibility and comparison of responses to inhaled histamine and methacholine. Thorax l978; 33:705-710. Cockcroft DW, Ruffin RE, Frith PA, Cartier A, Juniper EF, Dolovich J, Hargreave FE. Determinants of allergen-induced asthma: dose of allergen, circulating IgE antibody concentration, and bronchial responsiveness to inhaled histamine. Am Rev Respir Dis l979; l20:l053-1058. Juniper EF, Cartier A, Trebilcock AL, Frith PA, Dolovich J, Hargreave FE. Effects of oxatomide compared with chlorpheniramine in allergic rhinoconjunctivitis. Clin Allergy 1981; 11:61-66. Frith PA, Ruffin RE, Juniper EF, Dolovich J, Hargreave FE. Inhibition of allergen-induced asthma by three forms of sodium cromoglycate. Clin Allergy l98l; 11:67-77. Ryan G, Dolovich MB, Obminski G, Cockcroft DW, Juniper EF, Hargreave FE, Newhouse MT. Standardization of inhalation provocation tests: influence of nebulizer output, particle size and method of inhalation. J Allergy Clin Immunol 1981; 67:156-164. Ryan G, Dolovich MB, Roberts RS, Frith PA, Juniper EF, Hargreave FE, Newhouse MT. Standardization of inhalation provocation tests: two techniques of aerosol generation and inhalation compared. Am Rev Respir Dis l98l; l23:l95-199. Juniper EF, Frith PA, Hargreave FE. Airway responsiveness to histamine and methacholine: relationship to minimum treatment to control symptoms of asthma. Thorax l98l; 36:575-579. Hargreave FE, Ryan G, Thomson NC, O'Byrne PM, Latimer K, Juniper EF, Dolovich J. Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance. J Allergy Clin Immunol l98l; 68:347-355. Juniper EF, Frith PA, Hargreave FE. Long term stability of airway responsiveness to histamine. Thorax l982; 37:288-291. Burdon JGW, Juniper EF, Killian KJ, Hargreave FE, Campbell EMJ. The perception of breathlessness in asthma. Am Rev Respir Dis l982; l26:825-828. Hargreave FE, Thomson NC, O'Byrne PM, Latimer K, Juniper EF. Bronchial responsiveness to histamine or methacholine in asthma; measurement and clinical significance. Eur J Respir Dis l982; 63(121):79-88. Juniper EF, Syty-Golda M, Hargreave FE. Histamine inhalation tests: inhalation of aerosol via a facemask versus a valve box with mouthpiece. Thorax l984; 39:556-557. Rosenfeld J, Juniper EF, Hargreave FE. Gas chromatographic determination of methylcholine chloride in pharmaceutical preparations. J Chrom l984; 287:433-437. Boulet L-P, Latimer KM, Roberts RS, Juniper EF, Cockcroft DW, Thomson NC, Daniel EE, Hargreave FE. The effect of atropine on allergen-induced increases in bronchial responsiveness to histamine. Am Rev Respir Dis l984; l30:368-372. Hargreave FE, Ramsdale EH, Sterk PJ, Juniper EF. Advances in the use of inhalation provocation tests in clinical evaluation. Chest l985; 87:S32-S35. Ryan G, Latimer KM, Juniper EF, Roberts RS, Hargreave FE. Effect of beclomethasone dipropionate on bronchial responsiveness to histamine in controlled nonsteroid-dependent asthma. J Allergy Clin Immunol l985; 75:25-30. Juniper EF, Roberts RS, Kennedy LK, O'Connor J, Syty-Golda M, Dolovich J, Hargreave FE. Polyethylene glycol-modified ragweed pollen extract in rhinoconjunctivitis. J Allergy Clin Immunol l985; 75:578-585. Juniper EF, Latimer KM, Morris MM, Roberts RS, Hargreave FE. Airway responses to hyperventilation of cold dry air: duration of protection by cromolyn sodium. J Allergy Clin Immunol 1986; 78:387-391. Juniper EF, O'Connor J, Roberts RS, Evans S, Hargreave FE Dolovich J. Polyethylene glycol modified ragweed extract: comparison of two treatment regimens. J Allergy Clin Immunol 1986; 78:851-856. Kirby JG, Juniper EF, Hargreave FE, Zamel N. Total lung capacity does not change during methacholine stimulated airway narrowing. J Appl Physiol 1986; 61(6):2144-2147. Juniper EF, Kline PA, Roberts RS, Hargreave FE, Daniel EE. Airway responsiveness to methacholine during the natural menstrual cycle and the effect of oral contraceptives. Am Vanzieleghem MA, Juniper EF. A comparison of budesonide and beclomethasone dipropion-ate nasal aerosols in ragweed-induced rhinitis. J Allergy Clin Immunol 1987; 79:887-892. Juniper EF, Kline PA, Morris MM, Hargreave FE. Airway constriction by isocapnic hyperventilation of cold dry air: comparison of magnitude and duration of protection by nedocromil sodium and sodium cromoglycate. Clin Allergy 1987, 17:523-528. Juniper EF, White J, Dolovich J. Efficacy of continuous treatment with astemizole (Hismanal) and terfenadine (Seldane) in ragweed pollen-induced rhinoconjunctivitis. J Allergy Clin Immunol 1988; 82:670-675. Juniper EF, Kline PA, Hargreave FE, Dolovich J. Comparison of beclomethasone dipropionate aqueous nasal spray, astemizole and the combination in the prophylactic treat-ment of ragweed pollen-induced rhinoconjunctivitis. J Allergy Clin Immunol 1989; 83:627-633. Juniper EF, Daniel EE, Roberts RS, Kline PA, Hargreave FE, Newhouse MT. Improvement in airway responsiveness and asthma severity during pregnancy. Am Rev Respir Dis 1989; 140: 924-31. Israel E, Juniper EF, Callaghan JT, Mathur PN, Morris MM, Dowell AR, Enas GG, Hargreave FE, Drazen JM. Effect of a leukotriene antagonist, LY171883, on cold air-induced broncho-constriction in asthmatics. Am Rev Respir Dis 1989; 140: 1348-1353. Juniper EF, Kline PA, Ramsdale EH, Hargreave FE. Comparison of the efficacy and side effects of aqueous steroid nasal spray (budesonide) and allergen-injection therapy (Pollinex-R) in the treatment of seasonal allergic rhinoconjunctivitis. J Allergy Clin Immunol 1990; 85: 606-611. Juniper EF, Kline PA, Vanzeileghem MA, Ramsdale EH, O'Byrne PM, Hargreave FE. Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyper-responsiveness and clinical asthma in nonsteroid-dependent asthmatics. Am Rev Respir Dis 1990; 142: 832-836. Juniper EF, Guyatt GH, O'Byrne PM, Viveiros M. Aqueous beclomethasone dipropionate nasal spray: regular versus 'as required' use in the treatment of seasonal allergic rhinitis. J Allergy Clin Immunol 1990; 86: 380-386. Juniper EF, Kline PA, Vanzeileghem MA, O'Byrne PM, Ramsdale EH, Hargreave FE. Long-term effects of budesonide on airway responsiveness and clinical asthma severity in inhaled -steroid-dependent asthmatics. Eur Respir J 1990; 3: 1122-1127. Juniper EF, Kline PA, Vanzieleghem MA, Hargreave FE. Reduction of budesonide after a year of increased use: a randomised controlled trial to evaluate whether improvements in airway responsiveness and clinical asthma are maintained. J Allergy Clin Immunol 1991; 87: 483-489. Juniper EF, Guyatt GH. Development and testing of a new measure of health status for clinical trials in rhinoconjunctivitis. Clin Exper Allergy 1991; 21: 77-83. Juniper EF, Daniel EE, Roberts RS, Kline PA, Hargreave FE, Newhouse MT. Effect of pregnancy on airway responsiveness and asthma severity. Relationship to serum progesterone. Am Rev Respir Dis 1991;143: S78. Juniper EF, Guyatt GH, Epstein RS, Ferrie PJ, Jaeschke R, Hiller TK. Evaluation of impairment of health-related quality of life in asthma: development of a questionnaire for use in clinical trials. Thorax 1992; 47: 76-83. Juniper EF, Willms DG, Guyatt GH, Ferrie PJ. Aqueous beclomethasone dipropionate nasal spray in the treatment of seasonal (ragweed) rhinitis. Can Med Assoc J 1992; 147: 887-892. Sterk PJ, Fabbri LM, Quanjer PhH, Cockcroft DW, O'Byrne PM, Anderson SD, Juniper EF, Malo J-L. Airway responsiveness. In: Standardized lung function testing: Official Statement of the European Respiratory Society. Europ Respir J 1993; 6: 54-79. Juniper EF, Guyatt GH, Andersson B, Ferrie PJ. Comparison of powder and aerosolized budesonide in perennial rhinitis: validation of rhinitis quality of life questionnaire. Annals Allergy 1993; 70: 225-230 Juniper EF, Guyatt GH, Ferrie PJ, Griffith LE. Measuring quality of life in asthma. Am Rev Respir Dis 1993; 147: 832-838. Malo JL, Boulet LP, Dewitte JD, Cartier A, L'Archeveque J, Cote J, Bedard G, Boucher S, Champagne F, Tessier G, Contandriopoulos AP, Juniper EF, Guyatt GH. Quality of life of subjects with occupational asthma. J Allergy Clin Immunol 1993; 91: 1121-1127. Cook DJ, Guyatt GH, Juniper EF, McIlroy W, Willan A, Jaeschke R, Epstein R. Interviewer versus self-administered questionnaires in developing a disease-specific, health-related quality of life instrument for asthma. J Clin Epidemiol 1993; 46: 529-534. Juniper EF, Guyatt GH, Archer B, Ferrie PJ. Aqueous beclomethasone dipropionate in the treatment of ragweed pollen induced rhinitis: further exploration of prn use. J Allergy Clin Immunol 1993; 92: 66-72. Cook DJ, Guyatt GH, Adachi JD, Clifton J, Griffith LE, Epstein RS, Juniper EF. Quality of life in women with vertebral fractures due to osteoporosis. Arthritis Rheum 1993; 36: 750-756. Juniper EF, Guyatt GH, Willan A, Griffith LE. Determining a minimal important change in a disease-specific quality of life instrument. J Clin Epidemiol 1994; 47: 81-87. Juniper EF, Guyatt GH, Dolovich J. Assessment of quality of life in adolescents with allergic rhinoconjunctivitis: development and testing of a questionnaire for clinical trials. J Allergy Clin Immunol 1994; 93: 413-423. Juniper EF, Guyatt GH, Ferrie PJ, King DR. Sodium cromoglycate eye drops: regular versus 'as needed' use in the treatment of seasonal allergic conjunctivitis. J Allergy Clin Immunol 1994; 94: 36-43. International Rhinitis Management Working Group. International consensus report on the diagnosis and management of rhinitis. Allergy 1994; S19: 5-34. Juniper EF, Johnston PR, Borkhoff CM, Guyatt GH, Boulet LP, Haukioja A. Quality of life in asthma clinical trials: comparison of salmeterol and salbutamol. Am J Respir Crit Care Med 1995; 151: 66-70. Juniper EF. Quality of life considerations in the treatment of asthma. Pharmacoeconomics 1995; 8: 123-128. Sanjuas C, Alonso J, Sanchis J, Casan P, Broquetas JM, Ferrie PJ, Juniper EF, Anto JM. The quality of life questionnaire with asthma patients; the Spanish version of the Asthma Quality of Life Questionnaire. Archivos de Bronconeumologia 1995; 31: 219-226. Juniper EF. Valutazione della qualita di vita nel paziente asmatico. Rassegna di Patologia dell’Apparto Respiratorio 1995; 10: 59-69. Juniper EF, Guyatt GH, Feeny DH, Ferrie PJ, Griffith LE, Townsend M. Measuring quality of life in children with asthma. Qual Life Res 1996; 5: 35-46. Juniper EF, Guyatt GH, Feeny DH, Ferrie PJ, Griffith LE, Townsend M. Measuring quality of life in the parents of children with asthma. Qual Life Res 1996; 5: 27-34. Juniper EF, Ponte CD, Shapiro GG. Drug spotlight: the newer antihistamines. Patient Care 1996; vol30, #4: 34-48. Juniper EF, Guyatt GH, Griffith LE, Ferrie PJ. Interpretation of rhinoconjunctivitis quality of life questionnaire data. J Allergy Clin Immunol 1996; 98: 843-845. Harrison MB, Juniper EF, Mitchell-DiCenso A. Quality of life as an outcome measure in nursing research. May you have a long and healthy life. Can J Nursing Res 1996; 28: 49-68. Guyatt GH, Juniper EF, Feeny DH, Griffith LE. Children and adult perceptions of childhood asthma. Pediatrics 1997; 99: 165-168. Juniper EF. Measuring health-related quality of life in rhinitis. J Allergy Clin Immunol 1997; 99: S742-9. Santanello NC, Barber BL, Reiss TF, Friedman BS, Juniper EF, Zhang J. Measurement characteristics of two asthma symptom diary scales for use in clinical trials. Eur Respir J 1997; 10: 646-651. Juniper EF, Guyatt GH, Streiner DL, King DR. Clinical impact versus factor analysis for quality of life questionnaire construction. J Clinical Epidemiology 1997; 50: 233-238. Juniper EF, Ferrie PJ, Guyatt GH, Griffith LE. First-line treatment for seasonal (ragweed) rhinoconjunctivitis: a randomized management trial comparing a nasal steroid and a nonsedating antihistamine. Can Med Assoc J 1997; 156: 1123-31. Juniper EF. Assessing quality of life in adults and children with asthma and rhinitis. Allergy Clin Immunol Internat 1997; 9: 5-9. Guyatt GH, Naylor CD, Juniper EF, Heyland DK, Jaeschke R, Cook DJ for the Evidence-Based Medicine Working group. Users' guides to the medical literature. XII How to use articles about health-related quality of life. JAMA 1997; 277: 1232-1237. Juniper EF. Assessing health-related quality of life in asthma. Can Respir J 1997; 4: 145-151. Juniper EF. How important is quality of life in pediatric asthma? Pediatric Pulmonology 1997; S15: 27-31. Juniper EF. The value of quality of life in asthma. Eur Respir Rev 1997; 49: 333-337. Juniper EF. Quality of life in adults and children with asthma and rhinitis. Allergy 1997; 52: Juniper EF. Rhinitis and quality of life. Eur Respir Rev 1997; 7: 300-302. Juniper EF, Guyatt GH, Feeny DH, Griffith LE, Ferrie PJ. Minimum skills required by children to complete health-related quality of life instruments for asthma: comparison of measurement properties. Eur Respir J 1997; 10: 2285-2294. Juniper EF. Evaluating quality of life in adults and children with asthma. Clinical Asthma Reviews 1997; 1: 161-171. Juniper EF, Howland WC, Roberts NB, Thompson AK, King DR. Measuring quality of life in children with rhinoconjunctivitis. J Allergy Clin Immunol 1998; 101: 163-170. Guyatt GH, Juniper EF, Walter SD, Griffith LE, Goldstein RS. Interpreting treatment effects in randomised trials. Br Med J 1998; 316: 690-693. Juniper EF. Impact of upper respiratory allergic diseases on quality of life. J Allergy Clin Immunol 1998; 101: S386-391. Heyland DK, Guyatt GH, Cook DJ, Meade M, Juniper EF, Cronin L, Gafni A. The frequency and methodological rigor of quality of life assessments in the critical care literature. Crit Care Med 1998; 26: 591-598. Juniper EF. Quality of life questionnaires: does statistically significant = clinically important? (Editorial) J Allergy Clin Immunol 1998; 102: 16-17. Juniper EF. Effect of asthma on quality of life. Can Respir J 1998; 5: 77-84A. Juniper EF. Rhinitis management: the patient’s perspective. Clin Exper Allergy 1998; 28: 34-38. Juniper EF. Health-related quality of life in asthma. Curr Opin Pulm Med 1999; 5: 105-110. Juniper EF, Buist AS, Cox FM, Ferrie PJ, King DR. Validation of a standardized version of the Asthma Quality of Life Questionnaire. Chest 1999; 115: 1265-1270. Juniper EF, Guyatt GH, Cox FM, Ferrie PJ, King DR. Development and validation of the Mini Asthma Quality of Life Questionnaire. Eur Respir J 1999; 14: 32-38. Juniper EF. Interpreting of quality of life data. Quality of Life Newsletter 1999; 23: 3. Juniper EF, Thompson AK, Ferrie PJ, Roberts JN. Validation of a standardized version of the Rhinoconjunctivitis Quality of Life Questionnaire. J Allergy Clin Immunol 1999; 104: 364-9. Juniper EF, O’Byrne PM, Guyatt GH, Ferrie PJ, King DR. Development and validation of a questionnaire to measure asthma control. Eur Respir J 1999; 14: 902-7. Juniper EF, Svensson K, O’Byrne PM, Barnes PJ, Bauer C-A, Lofdahl C-GA, Postma DS, Pauwels RA, Tattersfield AE, Ullman A. Asthma quality of life during one year of treatment with budesonide with or without formoterol. Eur Respir J 1999; 14: 1038-43. Juniper EF, Buist AS, the study group. Health-related quality of life in moderate asthma: 400µg hydrofluoroalkane- versus 800µg chlorofluorocarbon- beclomethasone dipropionate. Chest 1999; 116: 1297-1303. Juniper EF, Thompson AK, Ferrie PJ, Roberts JN. Development and validation of the Mini Rhinoconjunctivitis Quality of Life Questionnaire. Clin Exper Allergy 2000; 30: 132-140. van Cauwenberge P, Juniper EF, Star Study Investigating Group. Comparison of the efficacy, safety, and quality of life provided by fexofenadine hydrochloride 120mg, loratadine 10mg, and placebo administered once daily for the treatment of seasonal allergic rhinitis. Clin Exper Allergy 2000; 30: 891-899 Juniper EF, O’Byrne PM, Ferrie PJ, King DR, Roberts JN. Measuring asthma control: clinic questionnaire or daily diary? Am J Respir Crit Care Med 2000; 162: 1330-1334. Thompson AK, Meltzer EO, Juniper EF. Quality of life in patients with allergic rhinitis. Annals Allergy Asthma Immunol 2000; 85: 338-348. Moy ML, Israel E, Weiss ST, Juniper EF, Dube L, Drazen JM. Clinical predictors of health-related quality of life depend on asthma severity. Am J Respir Crit Care Med 2001; 163: 924-929. Juniper E. Rhinitis and quality of life. Rev Fr Allergol Immunol Clin 2001: 41: 111-115. Juniper EF, O'Byrne PM, Roberts JN. Measuring asthma control in group studies: do we need airway calibre and rescue 2-agonist use? Respiratory Medicine 2001; 95: 319-323. Juniper EF, Norman GR, Cox FM, Roberts JN. Comparison of the standard gamble, rating scale, AQLQ and SF-36 for measuring quality of life in asthma. Eur Respir J 2001; 18: 38-44. Lanier BQ, Gross RD, Marks BB, Cockrum PC, Juniper EF. Olopatadine ophthalmic solution adjunctive to loratadine compared to loratadine alone in patients with active seasonal allergic conjunctivitis symptoms. Ann Allergy 2001; 86: 641-8. Juniper EF. Using humanistic health outcomes data in asthma. Pharmacoeconomics 2001; 19 Suppl 2: 13-19. Juniper EF. Health-related quality of life in asthma. Allergy Clin Immunol Int 2001; 13: 279-280. Juniper EF. (Editorial) Quality of life and rhinitis: nothing to be sneezed at!. Expert Rev Pharmacoeconomics Outcomes Res 2001; 1(2) 121-123. Caro JJ, Caro I, Caro J, Wouters F, Juniper EF. Does Electronic implementation of questionnaires used in asthma alter responses compared to paper implementation. Qual Life Res 2001; 10: 683-691. Juniper EF, Thompson AK, Roberts JN. Can the standard gamble and rating scale be used to measure quality of life in rhinoconjunctivitis? Comparison with the RQLQ and SF-36. Allergy 2002; 57: 201-206. Juniper EF. Health-related quality of life in asthma. Practical Issues in Asthma Management 2002; 32: 3-8. Juniper EF. Can quality of life be quantified? Clin Exper Allergy Rev 2002; 2: 57-60. Juniper EF, Price DB, Stampone P, Creemers JPHM, Mol SJM, Fireman P. Improvements in asthma quality of life but maintenance of conventional clinical indices in patients changed from CFC-BDP to approximately half the dose of HFA-BDP. Chest. 2002:121:1824-1832. Guyatt GH, Norman GR, Juniper EF, Griffith LE. A critical look at transition ratings. J Clin Epidemiol 2002; 55: 900-908. Juniper EF, Jenkins C, Price MJ, James MH. Impact of inhaled salmeterol/fluticasone proprionate combination product versus budesonide on the health-related quality of life of asthma patients. Am J Respir Med 2002; 1: 435-440. Juniper EF The impact of patient compliance on effective asthma management. Cur Opin Pulm Med 2003;9: (Suppl.1): S8-S10. Juniper EF, Rohrbaugh T, Meltzer EO. A questionnaire to measure health-related quality of life in adults with nocturnal allergic rhinoconjunctivitis. J Allergy Clin Immunol 2003; 111: 484-90. Stahl E, Postma DS, Juniper EF, Svensson K, Mear I, Lofdahl C-G. Health-related quality of life in asthma studies. Can we combine data from different countries? Pulmonary Pharmacology and Therapeutics 2003; 16: 53-59. Van der Molen T, Willemse BWM, Schokker SS, ten Hacken NHT, Postma DS, Juniper EF. Development, validity and responsiveness of the Clinical COPD Questionnaire. Health and Quality of Life Outcomes 2003; 1:13.(Electronic journal) Juniper EF (Editorial). Interpreting quality of life data: should we listen to the patients or the clinician? Annals Allergy, Asthma and Immunol 2003; 91:115 Juniper EF. Is there a place for quality of life in the routine management of asthma patients? Leukotriene Research and Clinical Review 2003; Juniper EF, Svensson K, Mörk A-C, Ståhl E. Measuring health-related quality of life in adults during an acute asthma exacerbation. Chest 2004; 125: 93-97. Juniper EF, Wisniewski ME, Cox FM, Emmett AH, Nielsen KE, O’Byrne PM. Relationship between quality of life and measures of clinical status in asthma: a factor analysis. Eur Respir J 2004; 23: 287-291. Pinnock H, Sheikh A, Juniper EF. Evaluation of an intervention to improve successful completion of the Mini-AQLQ: comparison of postal and supervised completion. Primary Care Respir J 2004; 13: 36-41. Juniper EF. Å måle livslvalitet ved astma. Allergi i Praxis 2004; 3: 28-33. Juniper EF, Chauhan A, Neville E, Chatterjee A, Svensson K, Mörk A-C, Ståhl E. Clinicians tend to overestimate improvements in asthma control: an unexpected observation. Primary Care Respir J 2004; 13: 181-184 Raat H, Bueving HJ, de Jongste JC, Grol MH, Juniper EF, van der Wouden JC. Responsiveness, Longitudinal and cross-sectional construct validity of the Paediatric Asthma Quality of Life Questionnaire (PAQLQ) in a Dutch population of children with asthma. Quality of Life Research 2005; 14: 265-72. Juniper EF. Assessing asthma quality of life: its role in clinical practice. Breathe 2005; 1: 193-204. (CME credit course) Juniper EF, Ståhl E, Doty RL, Simons FER, Allen DB, Howarth PH. Clinical outcomes and adverse effect monitoring in allergic rhinitis. J Allergy Clin Immunol 2005; 115 (3 pt.2): S390-413. Juniper EF, Svensson K, Mörk AC, Ståhl E. Measurement properties and interpretation of three shortened versions of the asthma control questionnaire. Respir Med 2005; 99: 553-8. 122. Pinnock H, Juniper EF, Aziz S. Comparison of postal vs supervised responses to the Mini Asthma Quality of Life and Asthma Control Questionnaires. J Clin Epidemiol 2005; 58: 809-814. Juniper EF, Svensson K, Mörk AC, Ståhl E. Modification of the Asthma Quality of Life Questionnaire (standardised) in patients 12 years and older. Health and Quality of Life Outcomes. Health and Quality of Life Outcomes 2005, 3:58 (16Sep2005) Tinkelman DG, Price DB, Nordyke RJ, Halbert RJ, Isonaka S, Nonikov D, Juniper EF, Freeman D, Hausen T, Levy ML, Østrem A, van der Molen T, van Schayck CP. Symptom-based questionnaire for differentiating COPD and asthma. Respiration 2005 (published online December 5th) Price DB, Tinkelman DG, Halbert RJ, Nordyke RJ, Isonaka S, Nonikov D, Juniper EF, Freeman D, Hausen T, Levy ML, Østrem A, van der Molen T, van Schayck CP. Symptom-based questionnaire for identificating chronic obstructive pulmonary disease in smokers in smokers. Respiration 2005 (published online December 5th) Juniper EF, Molen van der T. How to use the asthma control questionnaire as a tool in daily clinical practice. Caravisie, 2005;4:8-10. Juniper EF, Bousquet J, Abetz L, Bateman ED. Identifying ‘well-controlled’ and ‘not well-controlled’ asthma using the Asthma Control Questionnaire. Respir Med 2006; 100: 616- 621. Juniper EF, Riis B, Juniper BA. Development and validation of an electronic version of the Rhinoconjunctivitis Quality of Life Questionnaire. Allergy 2007; 62: 1091-3. Juniper EF. Assessing asthma control. Curr Allergy Asthma Reports 2007; 7: 390-394 Raat H, Mangunkusumo RT, Mohangoo AD, Juniper EF, Van Der Lei J. Internet and written respiratory questionnaires yield equivalent results for adolescents. Pediatric Pulmonology 2007; 42: 357-361. Newcombe PA, Sheffield JK, Juniper EF, Marchant JM, Halsted RA, Masters B, Chang AB. Development of a parent-proxy quality of life chronic cough questionnaire. Chest 2008; 133: 386-395. Juniper EF, Schatz M, Juniper BA, Zeiger RS. Evaluation of two interactive voice response telephone versions of health-related quality of life questionnaires. J Allergy Clin Immunol 2008; 122: 654-655. Marchant JM, Newcombe PA, Juniper EF, Sheffield JK, Stathis SL, Chang AB. What is the
burden of chronic cough for families? Chest 2008; 134: 303-309.
Juniper EF, Langlands JM, Juniper BA. Patients may respond differently to paper and electronic versions of the same questionnaires. Respiratory Medicine 2009; 103: 932-4. Juniper EF. Modification, translation and adaptation of questionnaires: should copyright laws be observed? Quality of Life Research 2009; 18: 531-3. Juniper EF. Medical questionnaires are copyrighted to ensure that validity is maintained. Chest 2009; 136:951-952. (Editorial) Juniper EF. Validated questionnaires should not be modified. Eur Respir J 2009; 34: 1015 - 1017. (Editorial) Olajos-Clow J, Minard J, Szpiro K, Juniper EF, Turcotte S, Jiang X, Jenkins B, Lougheed MD. Validation of an electronic version of the Mini Asthma Quality of Life Questionnaire. Respir Med 2010; 104: 658-667. Juniper EF, Gruffydd-Jones K, Ward S, Svensson K. Validation, measurement properties and interpretation of the Asthma Control Questionnaire in children. Eur Respir J 2010; 36: 1410-1416. Newcombe PA, Sheffield JK, Juniper EF, Petsky HL, Willis C, Chang A. Validation of a parent-proxy quality of life questionnaire for paediatric chronic cough (PC-QOL). Thorax 2010; 65: 819-823. Williams AE, Agier L, Wiklund I, Frith L, Gul N, Juniper EF. Transcultural and measurement evaluation of the Asthma Quality of Life Questionnaire. Health Outcomes Research in Medicine 2010; 1: e69-e79. Wilson ECF, Sims EJ, Musgrave S, Sims EJ, Shepstone L, Blyth A, Murdoch J, Mugford HM , Juniper EF, Ayres J, Wolfe S, Freeman D, Gilbert RFT, Harvey I, Price D. Cost effectiveness of leukotriene receptor antagonists versus inhaled corticosteroid for initial asthma controller therapy. Pharmacoeconomics 2010; 28: 585-95. Wilson ECF, Price D, Musgrave S, Sims EJ, Shepstone L, Murdoch J, Mugford HM, Blyth A, Juniper EF, Ayres J, Wolfe S, Freeman D, Gilbert RFT, Harvey I. Cost effectiveness of leukotriene receptor antagonists versus long-acting 2 agonists as add-on therapy to inhaled corticosteroids for asthma. Pharmacoeconomics 2010; 28: 597-608. 144. Price D, Musgrave SD, Shepstone L, Hillyer EV, Sims EJ, Gilbert RFT, Juniper EF, Ayres J, Kemp L, Blyth A, Wilson ECF, Wolfe S, Freeman D, Mugford M, Murdock J,, Harvey I. Leukotriene Antagonists as first-line or add-on asthma-controlled therapy. N Eng J Med 2011; 364:1695-707 SUBMITTED FOR PUBLICATION
Juniper EF, Gruffydd-Jones K, Mear I. Adapting an adult questionnaire for use in children (6-10 years): the Asthma Control Questionnaire. Pediatrics (Submitted)

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