Preliminary scientific program

Thursday, October 17, 2013

Plenary Session: Opening Ceremony

16:00 - 17:25
Welcome on behalf of Alzheimer Hellas
Welcome on behalf of ADI
Welcome on behalf of WFN Research Group on Dementia
Memory: to remember and to forget. History and theories
Plenary Session: Plenary Session 01

17:30 - 19:00
Research Challenges in a 2013 Predementia World
The relationship of brain ischemia to Alzheimer's pathology
Genetics of Stroke - Update and new developments
Discussion
Friday, October 18, 2013

Plenary Session: Plenary Session 02

08:30 - 10:00
TABASCO - Muldimodal approach for prediction of post - stroke demetia
Vascular factors in Alzheimer's dementia: what is the current evidence?
Cardiovascular risk factors, vascular brain injury and depression: evidence from a
large postmortem sample
L. Grinberg (USA/Brazil)
Discussion
Parallel Session: Is BBB dysfunction important in the pathogenesis of Subcortical Vascular Dementia?

10:30 - 12:00
Introduction
What does neuropathology tell us?
WHAT DO ANIMAL MODELS TELL US?
S. Schreiber, F. Held, S. Niklass, S. Stoyanov, K. Reymann, H.J. Heinze, C. Garz, C. Bueche (Germany) What do studies in patients tell us?
G.A. Rosenberg, A. Caprihan, J. Prestopnik, B. Huisa-Garate, J. Knoefel, J. Adair (USA) Discussion
Parallel Session: White matter and dementia

10:30 - 12:00
Leukoaraiosis - the magnitude of the problem
Standardisation of imaging criteria for SVD
Neuroimaging analysis of Alzheimer’s disease and MCI
Resting state network patterns in dementia
I. Rektorova, L. Krajcovicova, R. Marecek, M. Mikl (Czech Republic) Parallel Session: Mechanisms of Neurodegeneration

10:30 - 12:00
Apoptosis and oxidative stress in neurodegenerative diseases
A. Federico, P. Formichi, E. Radi (Italy) EXCITOTOXICITY AND VASCULAR DEMENTIA: THERAPEUTIC PERSPECTIVES.
Alteration of tight junction proteins expression in Alzheimer’s disease and vascular
dementia brains
B.O. Popescu (Romania)
The probable auto-antigenic role of lipids (anti-gangliosides antibodies) in the
pathogenesis of Alzheimer’s disease
E. Koutsouraki, E. Hatzifilippou, T. Banaki, V. Costa, S. Baloyannis (Greece)
Discussion
Parallel Session: Neuropsychiatric manifestations

10:30 - 12:00
CEREBROVASCULAR DISEASE AND LATE-LIFE DEPRESSION: DIFFERENT
ASPECTS OF INTERRELATIONS
L. Kruglov, I. Meshandin (Russia)
APATHY AND OTHER NEUROPSYCHIATRIC SYMPOTMS IN ALZHEIMER DISEASE
AND VASCULAR DEMENTIA
R. David, P. Robert (France)
The spectrum of psychosocial issues in patients with small vessel disease
Plenary Session: Towards a mechanism based treatment in neurocognitive disorders

13:00 - 14:30
Post - Stroke cognitive decline
Advances in neuropharmacology in brain protection and recovery
INCREASED VEGF LEVELS ARE ASSOCIATED TO ALZHEIMER'S DISEASE
SEVERITY
A. Alvarez, O. Iglesias, M. Aleixandre, C. Linares, J. Figueroa, D. Muresanu, H. Moessler
(Spain)
Neurotrophic Factors and Cognition
Discussion
Parallel Session: Diagnostic Criteria and Intervention

14:30 - 16:00
How is mixed dementia reflected in various sets of diagnostic criteria?
Biomarkers of Vascular Cognitive Impairment
Guidelines on disorders associated with Dementia
ANTI-Aß AUTOANTIBODIES AND ENDOTHELIAL DAMAGE DURING SPONTANEOUS
AMYLOID-RELATED IMAGING ABNORMALITIES (ARIA): REPORT FROM THE
INFLAMMATORY CEREBRAL AMYLOID ANGIOPATHY AND ALZHEIMER'S DISEASE
BIOMARKERS COLLABORATIVE NETWORK (ICAB)
F. Piazza, S.M. Greenberg, M. Savoiardo, R. Nitrini, H. Sakaguchi, G. Giaccone, F.
Tagliavini, A. Lleò Bisa, C. Ferrarese, J.C. DiFrancesco (Italy)
Discussion
Parallel Session: Cerebral small vessel disease in clinical practice

14:30 - 16:00
Nosological and diagnostic issues
Cognitive profiles of small vessel brain diseases
CSF deviations
G.A. Rosenberg, J. Thompson, B. Huisa-Garate, J. Knoefel, J. Adair, J. Prestopnik (USA) MRI characteristics
Discussion
Parallel Session: Animal Models of Vascular Dementia

14:30 - 16:00
Animal models of Chronic Brain Vascular Injury: Predictive of Vascular Dementia?
Cerebrovascular Dysfunction and Microvasculation Rarefaction in A Model of
Cerebral Ischemic Small Vessel disease: Effect on White Matter
A. Joutel (France)
A role for microvascular disease in cognitive impairment: Non-invasive detection by
Absolute Near Infra Red Spectroscopy (niaNIRS)
A. Troen (Israel)
Discussion
Parallel Session: Pathology

14:30 - 16:00
Vascular dementia, Alzheimer’s disease and LBD
MACHINE LEARNING CLASSIFICATION OF AUTOPSY PROVEN VASCULAR
COGNITIVE IMPAIRMENT AND ALZHEIMER'S DISEASE USING CONNECTED SPEECH
SAMPLING
V. Rentoumi, Y. Galbraith, L. Raoufian, S. Ahmed, P. Garrard (United Kingdom)
IMPORTANCE OF LOCATION OF DEEP OR INFRATENTORIAL MICROBLEEDS FOR
GLOBAL COGNITIVE DYSFUNCTION: THE KASHIMA SCAN STUDY
Y. Yakushiji, M. Eriguchi, T. Noguchi, M. Nishihara, Y. Nanri, M. Nishiyama, M. Hara, D.J.
Werring, H. Hara (Japan)
BLOOD-BRAIN BARRIER LEAKAGE IN ALZHEIMER’S DISEASE: A DYNAMIC
CONTRAST ENHANCED MRI STUDY
S. Burgmans, H. Van de Haar, M. Van Osch, J. Jansen, M. Van Buchem, P. Hofman, F.
Verhey, W. Backes (Netherlands)
Parallel Session: Neuropathology

16:30 - 18:00
Neuropathological aspects of vascular dementia – Alzheimer’s disease
Neuropathological assessment of vascular lesions – pitfalls and challenges
White matter pathology in vascular cognitive disease - challenges and opportunities
Assessment of hippocampal pathology in aged, an inter-rater study
T. Rauramaa, M. Pikkarainen, E. Englund, P.G. Ince, K. Jellinger, A. Paetau, I. Alafuzoff (Sweden) Discussion
Parallel Session: Chronic Hypoperfusion and Cognitive Impairment

16:30 - 18:00
MECHANISMS AND FEATURES OF CEREBRAL WHITE MATTER DETERIORATION IN
ADVANCED AGE
P. Kalvach, J. Keller, T. Peisker (Czech Republic)
Advanced MRI techniques to study the Microstructure of the Aging Brain
BRAIN DIFFUSION IN VASCULAR DEMENTIA – WHAT CAN WE SEE AND WHAT CAN
WE TRUST
J. Keller, P. Kalvach (Czech Republic)
Hippocampal Diffusion Tensor Imaging Microstructural Changes in Vascular
Dementia Suggesting Potential Stronger Connection with Alzheimer's Disease
D. Kozic, J. Ostojic, A. Pavlovic, N. ?ternic, M. Semnic, R. Semnic (Serbia)
Discussion
Parallel Session: Pathogenesis, treatment and outcome

16:30 - 18:00
THE OMENTUM IN THE TREATMENT OF ALZHEIMER, VASCULAR DEMENTIA AND
BINSWANGER DISEASE
H. Goldsmith (USA)
Protein trafficking and synaptic pathology in Alzheimer's disease
The dynamics of affective characteristics in the patients with the comorbidity of
cerebrovascular disease and depression
I. Meshandin, L.S. Kruglov (Russia)
Prospective follow-up study on cognitive impairment after ischemic stroke:
relationship to vascular risk factors
L. Traykov (Bulgaria)
Discussion
Parallel Session: Mild Cognitive Impairment A (MCI)

16:30 - 18:00
NEURAL AND CLINICAL CORRELATES OF MILD COGNITIVE IMPAIRMENT IN
PATIENTS WITH CORONARY HEART DISEASE
I. Tarasova, I. Syrova, R. Tarasov, O. Barbarash (Russia)
IS PREOPERATIVE MILD COGNITIVE IMPAIRMENT A PREDICTOR OF
POSTOPERATIVE COGNITIVE DYSFUNCTION IN PATIENTS AFTER ON-PUMP
CORONARY BYPASS SURGERY?
O. Trubnikova, A. Mamontova, I. Syrova, O. Maleva, O. Barbarash (Russia)
ORTHOSTATIC BLOOD PRESSURE REACTION PREDICTS MILD COGNITIVE
IMPAIRMENT IN THE GENERAL ELDER POPULATION. SIX-YEAR FOLLOW UP FROM
THE GOOD AGING IN SKÅNE COHORT (GÅS-SNAC), SWEDEN.
S. Elmståhl, E. Widerström (Sweden)
TESTAMENTARY CAPACITY AND INTENTION IN PATIENTS WITH DEMENTIA
P. Voskou, A. Douzenis, A. Economou, S. Papageorgiou (Greece) C-REACTIVE PROTEIN AND POST-STROKE COGNITIVE DECLINE IN CARRIERS AND
NON CARRIERS OF APOLIPOPROTEIN APOE4 GENOTYPE
E. Ben Assayag, E. Kliper, S. Shenhar-Tsarfaty, A. Mike, S. Usher, H. Hallevi, L. Shopin, A.
Hallevi, N.M. Bornstein, A.D. Korczyn (Israel)
STRESS, SEROTONIN GENETICS AND POST-STROKE DEMENTIA
S. Shenhar-Tsarfaty, E. Kliper, S. Usher, H. Hallevi, L. Shopin, A.D. Korczyn, T. Stadler, C. Kirschbaum, N.M. Bornstein, E. Ben Assayag (Israel) Discussion
Saturday, October 19, 2013

Plenary Session: Plenary session 03

08:30 - 10:00
Potential future interventions for preventing recurrent lacunar stroke and progression
of small vessel disease
J. Wardlaw, H. Pedder, M. MacLeod, P. Bath (United Kingdom)
Post Stroke Dementia prevention trials
VASCULAR PARKINSONISM, BINSWANGERS'S DISEASE AND NPH
Discussion
Parallel Session: Nutrition in dementia prevention: do we have a healthy recipe for the brain?

10:30 - 12:00
VITAMIN E COMPLEX AND DEMENTIA
F. Magialasche, M. Kivipelto, P. Mecocci (Sweden) Vitamin B12, homocysteine and dementia
B. Hooshmand, A. Solomon, T. Polvikoski, I. Kåreholt, F. Mangialasche, G. Kalpouzos, B. Winblad, M. Tanskanen, L. Myllykangas, E. Van Straaten, P. Scheltens, H. Soininen, R. Sulkava, L. Fratiglioni, M. Kivipelto (Sweden) Vitamin D and dementia
Medical food, cognitive impairment and dementia prevention
Discussion
Parallel Session: White matter rarefaction

10:30 - 12:00
The neuropathological concept of leucodystrophy
Link between white matter hyperintensities and cognitive functions
DO BRAIN T2W LESIONS CORRESPOND TO IRREVERSIBLE MYELIN LOSS IN
AGING?
P. Giannakopoulos, S. Haller, C. Bouras, E. Kovari (Greece)
Clinico Radiological correlations
Discussion
Parallel Session: Genetics

10:30 - 12:00
Genetics of vascular dementia and Alzheimer disease: Dissecting the pathways
through genetic signatures
J. Lee (USA)
Late onset Genetic and Degenerative Leucoencephalopathies with dementia
A. Federico, I. Di Donato, C. Battisti, I. Taglia, C. Stabile, S. Bianchi, M.T. Dotti (Italy) HYPOMORPHIC NOTCH3 ALLELES DO NOT CAUSE CADASIL IN HUMANS
J.W. Rutten, E.M.J. Boon, M.K. Liem, J.G. Dauwerse, M. Pont, M.J. Vollebregt, J.A. Maat- Kievit, H.B. Ginjaar, P. Lakeman, S.G. Van Duinen, G.M. Terwindt, S.A.J. Lesnik Oberstein (Netherlands) A HOMOZYGOUS RECESSIVE TRUNCATING MUTATION IN THE NOTCH3 GENE
ASSOCIATED WITH SEVERE CHILDHOOD-ONSET ARTERIOPATHY AND
CAVITATING LEUKOENCEPHALOPATHY
T. Pippucci, A. Maresca, P. Magini, G. Cenacchi, V. Donadio, C. Tonon, R. Liguori, A.
Parmeggiani, V. Carelli, M. Seri (Italy)
Discussion
Parallel Session: Therapy

10:30 - 12:00
Is it possible to treat vascular dementia?
Effect of carotid stenting on cognition
F. Vernieri, C. Altamura, D. Landi, P. Palazzo, R. Altavilla, S. Migliore, L. Quintiliani, D. Lupoi, F. Moffa, P. Maggio (Italy) NEUROTRANSLATIONAL ANALYSIS OF THE ROLE OF BRAIN-PENETRATING
ANGIOTENSIN-CONVERTING ENZYME INHIBITORS OVER COGNITIVE CHANGE IN
PATIENTS WITH DEMENTIA DUE TO ALZHEIMER’S DISEASE
F.F. Oliveira, P.H.F. Bertolucci, E.S. Chen, M.A.C. Smith (Brazil)
RATIONALE AND DESIGN OF THE CAROLINA-COGNITION TRIAL: A CAROLINA
SUBSTUDY ON COGNITIVE OUTCOMES OF LINAGLIPTIN VERSUS GLIMEPIRIDE IN
PATIENTS WITH TYPE 2 DIABETES MELLITUS
J. Janssen, G.J. Biessels, E. Van den Berg, O.E. Johansen (Netherlands)
HIGH RATES OF POTENTIALLY PREVENTABLE COMPLICATIONS IN HOSPITALISED
DEMENTIA PATIENTS: AUSTRALIAN COHORT STUDY
K. Bail, H. Berry, L. Grealish, B. Draper, R. Karmel, A. Peut, D. Gibson (Australia)
IMPACT OF TREATMENT WITH N-ACETYLCYSTEINE ON THE PATHOLOGICAL
CASCADE OF CEREBRAL SMALL VESSEL DISEASE IN SHR-SP
C.Z. Bueche, C. Garz, H. Braun, S. Kropf, H.J. Heinze, K.R. Reymann, S. Schreiber
(Germany)
COMPLETE RECOVERY OF COGNITION FOR SENESCENCE-ACCELERATED-PRONE
MICE BY ORAL REDOX-POLYMER THERAPEUTICS
Y. Nagasaki, P. Chonpathompikunlert, T. Yoshitomi, N. Imaizumi, Y. Ozaki (Japan)
Plenary Session: Plenary Session 04

13:00 - 14:30
STandards for ReportIng Vascular Changes on NEuroimaging (STRIVE) - outcomes of
the CoEN initiative
M. Duering (Germany)
The Pathophysiology of Post-Stroke Dementia
ACTIVATION OF ASPARAGINYL ENDOPEPTIDASE-SET-PP2A-TAU
HYPERPHOSPHORYLATION PATHWAY BY ACIDOSIS OF THE BRAIN
K. Iqbal (USA)
Discussion
Parallel Session: Alzheimer Disease and Vascular Pathology in Aging Brain

14:30 - 16:00
Cognition And Vascular Brain Aging: Time To Think Little
G. Gold, E. Kövari, P. Giannakopoulos, F.R. Herrmann, C. Bouras (Switzerland) Vascular and degenerative polypathologies in brain aging
DEMENTIA VS. CHRONIC CO-MORBIDITY AT OLD AGE: SIMILARITIES AND
DISSIMILARITIES IN MIDLIFE RISK FACTORS
U. Goldbourt, R. Balicer, I. Hekselman, M. Hoshen, D. Tanne, R. Ravona-Springer, M.
Scnaider-Beeri (Israel)
Discussion
Parallel Session: Neurotrophic Factors: Therapeutic Potential in ageing and cognitive decline

14:30 - 16:00
Neurotrophic factors: classification and MoA
Drugs with impact on Neurotrophic factors: evidence of efficacy from laborator
Neurocognitive Disorders – can we better match the neurobiology with therapeutics?
Drugs with impact on Neurotrophic factors: evidence of efficacy from clinical studies
Discussion
Parallel Session: Update on Susac Syndrome * a session dedicated to J.O. Susac

14:30 - 16:00
Lesion morphology at 7 Tesla MRI in Susac Syndrome
J. Dorr, T. Sinnecker, J. Wuerfel, F. Paul, T. Niendorf, I. Kleffner (Germany) RETINAL PATHOLOGY IN SUSAC SYNDROME DETECTED BY SPECTRAL DOMAIN
OPTICAL COHERENCE TOMOGRAPHY
M. Ringelstein, P. Albrecht, J. Harmel, B.P. Bühn, D. Finis, G. Geerling, I. Kleffner, H.P.
Hartung, J. Dörr, O. Aktas (Germany)
Diagnosis and scoring in Susac Syndrome
I. Kleffner, H. Wersching, M. Deppe, J. Dörr, M. Ringelstein, T. Duning (Germany) Specific and unspecific ocular findings in Susac Syndrome
Discussion
Parallel Session: Drug Therapy of Dementia

14:30 - 16:00
NEW INTERIM RESULTS (TWO YEARS OF TREATMENT) OF THE ASCOMALVA
(ASSOCIATION BETWEEN A CHOLINESTERASE INHIBITOR AND CHOLINE
ALPHOSCERATE IN ALZHEIMER’S DISEASE) TRIAL.
A. Francesco, A. Carotenuto, R. Rea, E. Traini, A.M. Fasanaro (Italy)
CHOLINESTERASE INHIBITORS PLUS ASSOCIATED TREATMENT FOR
PROLONGING THE EFFECTIVENESS OF PHARMACOTHERAPIES IN ALZHEIMER’S
DISEASE WITH VASCULAR INVOLVEMENT
E. Cumbo, L.D. Ligori, E. Traini (Italy)
Integration of genomic information in development of pharmacological vascular
dementia (VaD) prevention and treatment strategies
A. Baskys, J.X. Cheng (USA)
Pharmacoeconomics of treatment of Alzheimer's disease and Vascular dementia
Discussion
Parallel Session: CSF Biomarkers

16:30 - 18:00
CSF biomarkers for the differential diagnosis of Vascular dementia, Alzheimer's
disease and other dementias
A. De Vos, E. Stoops, V. Herbst, H. Struyfs, R. Constantinescu, S. Busse, K. Blennow, H.
Zetterberg, S. Engelborghs, B. Brix, H. Vanderstichele, E. Vanmechelen (Belgium)
DIFFUSION KURTOSIS IMAGING: A BIOMARKER FOR EARLY DIAGNOSIS OF
ALZHEIMER'S DISEASE.
H. Struyfs, W. Van Hecke, S. Slaets, S. Van der Mussele, L. Wuyts, B. Peters, F. De Belder,
P. Parizel, S. Engelborghs (Belgium)
PROTEIN MARKERS FOR THE DIFFERENTIAL DIAGNOSIS OF VASCULAR
DEMENTIA AND ALZHEIMER'S DISEASE
A.H. Simonsen, N.O. Hagnelius, G. Waldemar, T.K. Nilsson (Denmark)
Different cerebrospinal fluid biomarker patterns in subcortical vascular dementia and
Alzheimer’s disease
M. Bjerke (Sweden)
Discussion
Parallel Session: Mild Cognitive Impairment A (MCI)

16:30 - 18:00
Use of MCI as a target for dementia prevention Jose Lucshinger
MCI IN ELDERLY PATIENTS
N. Bachinskaya, V. Kholin, E. Demchenko, I. Pokrovenko, I. Rozheliuk, K. Polietaieva (Ukraine) ULTRASOUND SUBCLINICAL MARKERS IN DIAGNOSING VERY EARLY VASCULAR
CHANGES IN COGNITIVE IMPAIRMENT
V. Demarin (Croatia)
GLOBAL VASCULAR RISK AND SILENT BRAIN INFARCTS PREDICT MILD
COGNITIVE IMPAIRMENT IN A MEDITERRANEAN HYPERTENSIVE COHORT.
RESULTS FROM THE ISSYS STUDY.
Y. Riba Llena, C. Nafría Pérez, X. Mundet Tuduri, A. López Rueda, P. Fernández Lara, C.I.
Jarca, J.L. Tovar, F. Pujadas Navines, J. Montaner Villalonga, P. Delgado Martínez, I. On
behalf of the ISSYS Investigators (Spain)
VASCULAR INDEX CONTRIBUTES TO PHENOTIPIC VARIABILITY OF MCI.
A.M. Fasanaro, L. Colucci, I. Molino, A. Iavarone, F. Amenta (Italy) Discussion
Parallel Session: Imaging

16:30 - 18:00
IS CROSSED APHASIA A FULL CONCEPT? REVISITING THE CONCEPT USING
TRACTOGRAPHY ANALYSIS OF THE ARCUATE FASCICULUS OF PATIENTS WITH
POSTERIOR PARIETAL STROKE.
M.E. Lanna, A. Sapporta, T. Doring, T. Sanches Arruda, E. Gasparetto (Brazil)
MRI FEATURES OF CEREBRAL AUTOSOMAL RECESSIVE ARTERIOPATHY WITH
SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY (CARASIL)
H. Nozaki, Y. Sekine, Y. Nishimoto, Y. Shimoe, A. Shirata, S. Yanagawa, M. Hirayama, I.
Nakano, M. Nishizawa, O. Onodera (Japan)
ENLARGED PERIVASCULAR SPACES AS AN MRI MARKER OF PATHOLOGY-
PROVEN CEREBRAL AMYLOID ANGIOPATHY
A. Charidimou, Z. Jaunmuktane, J.C. Baron, M. Burnell, P. Varlet, A. Peeters, J. Xuereb,
H.R. Jäger, S. Brandner, D.J. Werring (United Kingdom)
WHITE MATTER CHANGES IN PATIENTS WITH ALZHEIMER'S DISEASE REVEALED
BY DIFFUSION TENSOR IMAGING
Y.M. Zhang, X.P. Gong, Y.J. Wang, C.X. Wang (China)
DELINEATION OF SUBCORTICAL APHASIA MECHANISMS BY DIFFUSION TENSOR
IMAGING(DTI)
Y. Zhang, X. Gong, H. Chen, Y. Wang (China)
STRUCTURAL INTEGRITY OF THE CONTRALESIONAL HEMISPHERE IN CHRONIC
STROKE PATIENTS: USEFUL BIOMARKERS OF COGNITIVE IMPAIRMENT
R. Dacosta-Aguayo, M. Graña, M. Fernández-Andújar, E. López-Cancio, C. Cáceres, N.
Bargallo, I. Clemente, A. Davalos, A. Tibor, M. Mataro (Spain)
ENLARGED PERIVASCULAR SPACES: RELATIONSHIP TO COGNITION AND SMALL
VESSEL DISEASE MRI MARKERS IN ISCHAEMIC STROKE AND TIA
R. Hurford, A. Charidimou, Z. Fox, L. Cipolotti, R. Jager, D. Werring (United Kingdom)
Discussion
Parallel Session: Neuropsychology

16:30 - 18:00
UNDERESTIMATION OF COGNITIVE IMPAIRMENTS BY THE MONTREAL COGNITIVE
ASSESSMENT (MOCA): A STUDY IN SUBACUTE STROKE
D. Werring, E. Chan, S. Khan, R. Oliver, S.K. Gill, L.I.S.A. Cipolotti (United Kingdom)
VASCULAR BRAIN DISEASE AND NEUROCOGNITIVE FUNCTION IN LONG-TERM
SURVIVORS OF CHILDHOOD HODGKIN LYMPHOMA
K.R. Krull, N.D. Sabin, W.E. Reddick, L. Zhu, G.T. Armstrong, D.K. Srivastava, L.L.
Robison, M.M. Hudson (USA)
EVALUATION OF MEMORY IMPAIRMENT AND DEMENTIA IN AGING ADULT
SURVIVORS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA TREATED WITH
CRANIAL RADIOTHERAPY
G. Armstrong, W.E. Reddick, R.C. Peterson, A. Santucci, Z. Zhang, D. Srivastava, R.J.
Ogg, C.M. Hillenbrand, N. Sabin, M.J. Krasin, L. Kun, C.H. Pui, M.M. Hudson, L.L. Robison
(USA)
BASELINE PREDICTORS OF COGNITIVE DECLINE IN PATIENTS WITH CEREBRAL
SMALL VESSEL DISEASE-EXPERIENCE FROM 294 SERBIAN CASES
A. Pavlovic, T. Pekmezovic, G. Tomic, J. Zidverc Trajkovic, N. Sternic (Serbia)
NEUROPHYSIOLOGICAL CORRELATIONS OF COGNITIVE IMPAIRMENT IN PATIENTS
AFTER STROKE
E. Melnikova, A. Razumov (Russia)
Discussion
Sunday, October 20, 2013

Plenary Session: Plenary Session 05

08:30 - 10:00
What can retinal imaging tell us about vascular brain disease?
DTI-based assessment of microvascular damage in brain aging
P. Giannakopoulos, S. Haller, K.O. Lovblad (Greece) Vascular dementia and seizures
Discussion
Parallel Session: Diabetes, Insulin and Cognitive Impairment

10:30 - 12:00
Diabetes and cognition throughout the lifespan
Diabetes and cognitive impairment in observational studies
Diabetes related strategies in the prevention and treatment of cognitive impairment
A LIFETIME PERSPECTIVE IS REQUIRED TO INVESTIGATE THE CAUSES OF
COGNITIVE IMPAIRMENT IN TYPE 2 DIABETES
D.G. Bruce, W.A. Davis, M. Nelson, J.L. Mace, S.E. Starkstein, T.M. Davis (Australia)
Why Alzheimer's disease may be called type 3 diabetes?
Parallel Session: Vascular Parkinsonism

10:30 - 12:00
Differential diagnosis of vascular with degenerative parkinsonism-dementia
syndrome
M. Stamelou (United Kingdom)
PET imaging of dementia in Movement Disorders
The impact of white matter hyperintensity in mild cognitive impairment in Parkinson's
J. Kulisevsky, J. Gomez-Ansón, J. Pagonabarraga, J. Fernández de Bobadilla (Spain) Discussion
Parallel Session: Pathological Processes

10:30 - 12:00
SCAVENGER RECEPTOR BI (SR-BI) REGULATES PERIVASCULAR MACROPHAGES
AND MODIFIES AMYLOID PATHOLOGY AND CEREBRAL AMYLOID ANGIOPATHY IN
AN ALZHEIMER’S DISEASE TRANSGENIC MOUSE
E. Paouri, L. Krikoni, K. Thanopoulou, S. Georgopoulos (Greece)
TARGETING VASCULAR AMYLOID IN ATERIOLES OF ALZHEIMER DISEASE
TRANSGENIC MICE WITH AMYLOID BETA PROTEIN ANTIBODY-COATED
NANOPARTICLES
J.F. Poduslo, K.L. Hultman, G.L. Curran, G.M. Preboske, R. Chamberlain, M. Marjanska, M.
Garwood, C.R. Jack, T.M. Wengenack (USA)
CYSTEINE QUANTITY CORRECTION IN CADASIL; MODIFICATION OF THE NOTCH3
PROTEIN USING EXON SKIPPING
S. Lesnik Oberstein, J. Rutten, J.G. Dauwerse, H. Venselaar, D.J.M. Peters, M.H. Breuning,
G.J.B. Van Ommen, A.M. Aartsma-Rus (Netherlands)
AXONAL DEGENERATION SECONDARY TO NEURODEGENERATIVE CORTICAL
LOSS: POTENIAL PATHOGENESIS OF WHITE MATTER LESIONS IN THE ABSENCE
OF SMALL VESSEL DISEASE?
K. McAleese, M. Firbank, S. McParland, J.T. O'Brien, J. Attems (United Kingdom)
ANTERIOR COMMUNICATING ARTERY SYNDROME IS DUE TO FORNIX LESIONS? A
NEUROPSYCHOLOGICAL AND DTT STUDY.
I. Molino, L. Colucci, E. Salvatore, M. Quarantelli, F. Amenta, G. Russo, A.M. Fasanaro
(Italy)
A NOVEL MECHANISM IN CEREBRAL AMYLOID ANGIOPATHY PATHOGENESIS:
TISSUE TRANSGLUTAMINASE-MEDIATED MODULATION OF EXTRACELLULAR
MATRIX IN THE CEREBRAL VESSEL WALL
M. Wilhelmus, M. De Jager, B. Drukarch (Netherlands)
MEMORY ENHANCING EFFECT OF CROCETIN AFTER CHRONIC CEREBRAL
HYPOPERFUSION IN RATS
S.A. Mohajeri, F. Tashakori-Sabzevar, H. Hosseinzadeh, V.S. Motamedshariaty (Iran)
Discussion

Parallel Session: Dementia Prevention

10:30 - 12:00
The role of neurosonology in the diagnosis of vascular dementia
The role of statins in the treatment of vascular dementia
Cardiovascular risk factors, small vessel disease and cognitive function
Is dementia preventable?
Discussion
Parallel Session: Superficial Siderosis of the Central Nervous System in Degenerative Dementia
Syndromes

12:15 - 13:45
Advanced MRI- what does it tell us about leukoaraiosis
PATHOGENESIS OF SUPERFICIAL SIDEROSIS: A 7.0 TESLA POST-MORTEM STUDY.
Cerebral amyloid angiopathy and the molecular pathogenesis of stroke and dementia
Predilection of cortical micro-bleeds in neurodegenerative and cerebrovascular
dementia syndromes: A 7.0 Tesla post-mortem MRI study
J. De Reuck (Belgium)
13:35 Discussion
Parallel Session: Driving in Mild Cognitive Impairment, Dementia

12:15 - 13:45
Assessing Driving Ability in the elderly: methodological issues
Assessing cognition in elderly drivers
Behavioral modifications in the elderly and driving
Mild Cognitive Impairment, Dementia and Driving: Concluding remarks
Discussion
Parallel Session: Multi- domain interventions

12:15 - 13:45
From observation to action in dementia prevention: the FINGER study and European
Dementia Prevention Initiative
M. Kivipelto (Sweden)
Participation in dementia prevention studies: Experiences from the ACCEPT study
A. Sandrine (France)
INTEGRATED APPROACH TO DETECTION AND CORRECTION OF VASCULAR
DYSGEMIAS IN REHABILITATION OF PATIENTS WITH DEMENTIA AND APALLIC
SYNDROME
U. Lushchyk, I. Babii, N. Lushchyk (Ukraine)
CHRONIC RAPAMYCIN RESTORES BRAIN VASCULAR INTEGRITY AND FUNCTION
THROUGH NO SYNTHASE ACTIVATION AND IMPROVES MEMORY IN SYMPTOMATIC
MICE MODELING ALZHEIMER'S DISEASE
A. Lin, V. Galvan (USA)
COMPARATIVE CLINICAL STUDY OF THE EFFECTIVENESS OF COMPUTER
COGNITIVE TRAINING IN PATIENTS WITH POST-STROKE COGNITIVE IMPAIRMENTS
WITHOUT DEMENTIA.
A. Bezdenezhnykh, S. Prokopenko, E. Mozheyko, T. Koryagina (Russia)
MEMORY AID – COMPUTER BASED WORKING MEMORY TRAINING IN ELDERLY
WITH MILD COGNITIVE IMPAIRMENT (MCI). A RANDOMIZED, CONTROLLED TRIAL.
M. Flak, S.S. Hernes, J. Skranes, G.C.C. Lohaugen (Norway)
Discussion

Source: http://cerebrolysin.com.ua/fileadmin/user_upload/conference_2013/10/Preliminary_Scientific_Program_10_2013.pdf