July 5, 1999

Tony R. Bai, MD, FRACP, FRCP(C), FACP

REFEREED PUBLICATIONS
(a) Journals:
1) Robinson GM, Bai TR, Steel RH. Nitrofurantoin induced chronic pulmonary
reaction: case report. N Z Med J. 91(652):50-52, 1980. 2) Bai TR, Webb D, Hamilton M. Treatment of hypertension with beta-adrenoceptor
blocking drugs. J R Coll Physicians Lond. 16(4), 4:239-241, 1982. 3) Bai TR. Sudden infant death syndrome (letter). N Eng J Med. 307 14:891, 1982.
4) Cooper CB, Bai TR, Heyderman E, Corrin B. Cellulose granuloma in the lungs of a
cocaine sniffer. Br Med J (Clin Res Ed). 286(6383):2021-2022, 1983. 5) Bai TR, Rabinovitch BJ, Pardy RL. Near-maximal voluntary hyperpnea and
ventilatory muscle function. J Appl Physiol. 57(6):1742-1748, 1984. 6) Shore SA, Bai TR, Wang CG, Martin JG. Central and local cholinergic components
of histamine-induced bronchoconstriction in dogs. J Appl Physiol. 58(2):443-451, 1985. 7) Bai TR, Macklem PT, Martin JG. The effects of parasympathectomy on
serotonin-induced bronchoconstriction in the cat. Am Rev Respir Dis. 133(1):110-115, 1986. 8) Bai TR, Macklem PT, Martin JG. Airway responses to aerosolized methacholine in
the cat: Effects of partial or complete vagosympathectomy. Am Rev Respir Dis. 135(1):190-193, 1987. 9) Isaacs RD, Wattle WJ, Wells AU, Rea HH, Bai TR. Massive haemoptysis as a late
consequence of pulmonary irradiation. Thorax. 42(1):77-78, 1987. 10) Cutten AE, Hasnain SM, Segedin BP, Bai TR, McKay EJ. The basidiomycete
ganoderma and asthma: collection, quantitation and immunogenicity of the spores. N Z Med J. 101(847 Pt 1):361-363. 1988. 11) Kolbe J, Bai TR. High-dose inhaled corticosteroids. N Z Med J. 102(862): 85,
12) Bai TR, Lam R, Prasad FY. Effects of adrenergic agonists and adenosine on
cholinergic neurotransmission in human tracheal smooth muscle. Pulm Pharmacol. 1(4):193-199, 1989. 13) Bai TR. Abnormalities in airway smooth muscle in fatal asthma. Am Rev Respir
14) Bai TR. Abnormalities in airway smooth muscle in fatal asthma. A comparison
between trachea and bronchus. Am Rev Respir Dis. 143(2):441-443, 1991. 15) Bai TR, Mak JC, Barnes PJ. A comparison of beta-adrenergic receptors and in
vitro relaxant responses to isoproterenol in asthmatic airway smooth muscle. Am J Respir Cell Mol Biol. 6(6):647-651, 1992. 16) Robinson P, Okazawa M, Bai TR, Paré PD. In vivo loads on airway smooth
muscle: The role of non-contractile airway structures. Can J Physiol Pharmacol. 70(4):602-606, 1992. 17) Bai TR. Beta2 adrenergic receptors in asthma: a current perspective. Lung.
18) Okazawa M, Bai TR, Wiggs BR, Paré PD. Airway smooth muscle (ASM)
shortening in excised canine lung lobes. J Appl Physiol. 74(4):1613-1621, 1993. 19) Bai TR, Zhou D, Aubert JD, Lizee G, Hayashi S, Bondy GP. Expression of β2-
adrenergic receptor messenger RNA in peripheral lung in asthma and chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 8(3):325-333, 1993. 20) Bai TR, Bramley AM. Effect of an inhibitor of nitric oxide synthase on neural
relaxation of human bronchi. Am J Physiol (Lung Cell Mol Physiol). 264 (5 Pt 1):L425-L430, 1993. 21) Kuwano K, Bosken CH, Paré PD, Bai TR, Wiggs BR, Hogg JC. Small airways
dimensions in asthma and chronic obstructive pulmonary disease. Am Rev Respir Dis. 148(5) :1220-1225, 1993. 22) Dahl R et al, on behalf of an International study group. A dose-ranging study of fluticasone propionate in adult patients with moderate asthma. Chest. 104:1352-8, 1993. [I was principal investigator at one of the sites of this study] 23) Wang ZL, Bramley AM, McNamara A, Paré PD, Bai TR. Chronic fenoterol
exposure increases in vivo and in vitro airway responses in guinea pigs. Am J Respir Crit Care Med. 149 (4 Pt 1):960-965, 1994. 24) Aubert JD, Dalal BI, Bai TR, Roberts CR, Hayashi S, Hogg JC. Transforming
growth factor-ß1 gene expression in human airways. Thorax. 49(3) :225-232, 1994. 25) Bai TR, Prasad FW. Epithelial modulation of cholinergic responses in human
tracheal smooth muscle. Can J Physiol Pharmacol. 72(3):199-204, 1994. 26) Aubert J-D, Hayashi S, Hards J, Bai TR, Paré PD, Hogg JC. Platelet-derived
growth factor and its receptor in lungs from patients with asthma and chronic airflow obstruction. Am J Physiol (Lung Cell Mol Physiol). 266 (6 Pt 1):L655-L663, 1994. 27) Bai TR, Eidelman DH, Hogg JC, James AL, Lambert RK, Ludwig MS, Martin J,
McDonald DM, Mitzner WA, Okazawa M, Pack RJ, Paré PD, Schellenberg RR, Tiddens HA, Wagner EM, Yager D. Proposed standard nomenclature for subdivisions of the airway wall. J App Physiol. 77:1011-1014, 1994. 28) Lilly CM, Bai TR, Shore SA, Hall AE, Drazen JM. Neuropeptide content of lungs
from asthmatic and non-asthmatic patients. Am J Respir Crit Care Med. 151(2 Pt 1):548-553, 1995. 29) Paré PD, Bai TR. The consequences of chronic allergic inflammation. Thorax.
30) Sasaki F, Paré PD, Ernest D, Bai TR, Verburgt L, March R, Baile E. Endogenous
nitric oxide influences acetylcholine-induced bronchovascular dilation in sheep. J
Appl Physiol. 78(2):539-545, 1995.
31) Bai TR, Zhou D, Weir T, Walker B, Hegele R, Hayashi S, McKay K, Bondy GP,
Fong T. Substance P (NK-1) and neurokinin A (NK-2) receptor gene expression in inflammatory airway diseases. Am J Physiol. 269(3 Pt 1):L309-317 1995. 32) Baile L, Mayo J, Sasaki F, Bai TR, Paré PD. Bronchial arterial response to contrast
medium. Acad Radiol. 2 (11):980-984, 1995. 33) Bai TR. Glucocorticosteroid treatment of asthma. Can Fam Physician. 41:1921-
34) Wang ZL, Walker BA, Weir TD, Yarema MC, Roberts CR, Okazawa M, Paré PD, Bai TR. Effect of chronic antigen and beta2 agonist exposure on airway
remodelling in guinea pigs. Am J Respir Crit Care Med. 152(6 Pt 1):2097-2104,
1995.
35) Bai TR, Wang ZL, Walker B, Paré PD. Chronic allergic inflammation induces
replication of airway smooth muscle cells in vivo in guinea pigs. Chest. 107(3 Suppl):93S, 1995. 36) Staples C, Brown MJ, Bai TR, Chan N. Clinico-Radiologic-Pathologic Conference.
Abnormal findings on chest radiographs of an asymptomatic patient. Can Assoc Radiol J. 47(2): 136-139, 1996. 37) Paré PD, Bai TR. Airway wall remodelling in COPD. Eur Respir Rev. 6:39, 259-
38) Walker BA, Jacobson MA, Knight DA, Salvatore CA, Weir T, Zhou D, Bai TR.
Adenosine A3 receptor expression and function in eosinophils. Am J Resp Cell Mol Biol. 16(5):531-537, 1997. 39) Boldt MJ, Bai TR. Utility of lactate dehydrogenase vs radiographic severity in the
differential diagnosis of Pneumocystis carinii pneumonia. Chest. 111(5):1187-92. 1997 40) Knight D, McKay K, Wiggs B, Schellenberg RR, Bai TR. Localization of leukaemia
inhibitory factor to airway epithelium and its amplification of contractile responses to tachykinins. Br J Pharmacol. 120(5):883-891. 1997 41) Hamid Q, Song Y, Kotsimbos TC, Minshall E, Bai TR, Hegele RG, Hogg JC.
Inflammation of small airways in asthma. J Allergy Clin Immunol. 100(1):44-51. 1997 42) Fitzgerald, JM, Grunfeld A, Paré PD, Levy RD, Newhouse MT, Hodder R, Chapman KJ, Abboud R, Lange B, Bai TR et al. The clinical efficacy of combination nebulized
anticholinergic
bronchodilator alone in acute asthma. Chest. 111:311-315, 1997. 43) Bai TR. Inhaled corticosteroids and the risk of cataracts. New Eng J Med.
44) Knight DA, Zheng X, Rocchini C, Jacobson M, Bai TR, Walker B. Adenosine A3
receptor stimulation inhibits migration of human eosinophils. J Leukoc Biol. 62(4):465-468, 1997. 45) Paré PD, Roberts CR, Bai TR, Wiggs BJ. The functional consequences of airway
remodelling in asthma. Monaldi Arch Chest Dis. 52:6, 589-596, 1997 46) Pare PD, Bai TR, Roberts CR. The structural and functional consequences of
chronic allergic inflammation of the airways. Ciba Found Symp. 206:71-86; discussion 86-9, 106-10. 1997 47) Bai TR. Animal models of airway inflammation and remodelling. Can Respir J.
48) Turner MO, Noertjojo K, Vedal S, Bai TR, Crump S, Fitzgerald JM. Risk factors for
near-fatal asthma. A case-control study in hospitalized patients with asthma. Am J Respir Crit Care Med. 157(6 Pt 1):1804-1809. 1998 49) Baile EM, McKay K, Wang L, Bai TR, Paré PD. NO does not mediate inhibitory
neural responses in sheep airway and bronchial vascular smooth muscle. J Appl Physiol. 84(3):809-814. 1998 50) Weir TD, Mallek N, Sandford AJ, Bai TR, Awadh N, Fitzgerald JM, Cockcroft, D,
James A, Liggett SB, Paré PD. beta2-Adrenergic receptor haplotypes in mild, moderate and fatal/near fatal asthma. Am J Respir Crit Care Med. 158(3):787-791. 1998 51) Bai TR. New asthma management guidelines. B.C .Med J. 40 (8): 338-343, 1998.
52) Knight DA, Lydell CP, Zhou D, Weir TD, Schellenberg RR, Bai TR. Leukemia
inhibitory factor (LIF) and LIF receptor in human lung. Distribution and regulation of LIF release. Am J Respir Cell Mol Biol. 20(4):834-841. 1999 53) Zheng, X, Knight DA, Zhou, D, Weir T, Peacock C, Schellenberg RR, Bai TR.
Leukemia inhibitory factor is synthesized and released by human eosinophils and modulates activation state and chemotaxis. J Allergy Clin Immunol. 104(1):136-144. 1999 54) Chagani T, Paré PD, Zhu S, Weir TD, Bai TR, Behbehani NA, Fitzgerald JM,
Sanford AJ. Prevalence Of Tumour Necrosis Factor-alpha And Angiotensin Converting Enzyme Polymorphisms In Mild/Moderate And Fatal/Near Fatal Asthma. Am J Respir Crit Care Med. 160(1): 278-282. 1999 55) Fitzgerald JM et al. Sustained bronchoprotection, bronchodilatation and symptom control during regular formoterol use in asthma of moderate or greater severity. J Allergy Clin Immunol. 103:427-35. 1999 [I was a site investigator of this multicenter study, and reviewed manuscript and data [see appendix to paper] 56) Knight DA, Bai TR. Roles for LIF in lung biology. Drug News and Perspectives. 12
57) Bai TR and Sears MR. Short and Long Acting Beta 2 Agonists. In: Guidelines for
the Management of Asthma. Canadian Medical Association Journal. 161 (Suppl 11):S28-S30. 1999 58) Bai TR, Cooper J, Koelmeyer T, Paré PD, Weir TD. The effect of age and duration
of disease on airway structure in fatal asthma. Am J Respir Crit Care Med. 162(2 Pt 1):663-669. 2000 59) FitzGerald JM, Shragge D, Haddon J, Jennings B, Lee J, Bai TR, Paré PD, Kassen
D, Grunfeld A. A randomized, controlled trial of high dose, inhaled budesonide versus oral prednisone in patients discharged from the emergency department following an acute asthma exacerbation. Can Respir J. 7(1):61-67. 2000 60) Sandford AJ, Chagani T, Zhu S, Weir TD, Bai TR, Spinelli JJ, Fitzgerald JM,
Behbehani NA, Tan WC, Paré PD. Polymorphisms in the IL4, IL4RA, and FCERIB genes and asthma severity. J Allergy Clin Immunol. 106(1 Pt 1):135-140. 2000 61) Anis AH, Lynd LD, Wang XH, King G, Spinelli JJ, Fitzgerald M, Bai TR, Paré PD.
Double trouble: impact of inappropriate use of asthma medication on the use of health care resources. CMAJ. 164(5):625-631. 2001 62) Press N, Montessori V, Bai TR, Montaner J. Respiratory failure associated with the
lipodystrophy syndrome in an HIV-positive patient with compromised lung function. Can Respir J. 8(4):279-282. 2001 63) Cook VJ, Coxson HO, Mason AG, Bai TR. Bullae, bronchiectasis and nutritional
emphysema in severe anorexia nervosa. Can Respir J. 8(5):361-365. 2001 64) Sandford AJ, Zhu Shoukang, Bai TR, Fitzgerald JM, Paré PD. The role of the C-C
chemokine receptor-5 Delta32 polymorphism in asthma and in the production of regulated on activation, normal T cells expressed and secreted. J Allergy Clin Immunol. 108(1):69-73. 2001 65) Boulet LP, Bai TR et al. What is new since the last (1999) Canadian Asthma
Consensus Guidelines? Can Respir J. 8 Suppl A:5A-27A. 2001 66) Zheng X, Karsan A, Duronio V, Chu F, Walker DC, Bai TR, Schellenberg RR.
Interleukin-3, but not granulocyte-macrophage colony-stimulating factor and interleukin-5, inhibits apoptosis of human basophils through phosphatidylinositol 3-kinase: requirement of NF-kappaB-dependent and -independent pathways. Immunology: 107(3):306-315. 2002 67) Bai TR. Do written self-management plans improve asthma control? The evidence
is not conclusive. Can Respir J. 10(3):155-6. 2003 68) Ensom MH, Chong G, Zhou D, Beaudin B, Shalansky S and Bai TR. Estradiol in
premenstrual asthma: a double-blind, randomized, placebo-controlled, crossover study. Pharmacotherapy. 23(5):561-71. 2003 69) Kuyper LM, Paré PD, Hogg JC, Lambert RK, Ionescu D, Woods R, Bai TR.
Characterization of airway plugging in fatal asthma. Am J Med. 115(1):6-11. 2003 70) Ensom MH, Chong G, Beaudin B, Bai TR. Estradiol in Severe Asthma with
Premenstrual Worsening. Ann Pharmacother. 37(11):1610-1613. 2003 71) Zhou D, Zheng X, Wang L, Stelmack G, Halayko AJ, Dorscheid D, Bai TR.
Expression and effects of cardiotrophin-1 (CT-1) in human airway smooth muscle cells. Br J Pharmacol. 140(7):1237-1244. 2003 72) Davidson W and Bai TR. Asthma: Clearing the Way. Can J Diagnosis. 11: 91-95.
73) Bai TR. Mucus plugging in asthma [letter]. Am J Med. 116 (1):67. 2004
74) Lemiere C, Bai TR, Balter M, Bayliff C, Becker A, Boulet LP, Bowie D, Cartier A,
Cave A, Chapman K, Cowie R, Coyle S, Cockcroft D, Ducharme FM, Ernst P, Finlayson S, FitzGerald JM, Hargreave FE, Hogg D, Kaplan A, Kim H, Kelm C, O'Byrne P, Sears M, Markham AW. Adult Asthma Consensus Guidelines Update 2003. Can Respir J. 11(Suppl A):9A-18A. 2004 75) Raghu G et al, for the Idiopathic Pulmonary Fibrosis Study Group*. A placebo- controlled trial of INF gamma in patients with IPF. New Eng J Med. 350:125-133. 2004. *I was Principal Investigator for the UBC site for this study, as listed in the manuscript. 76) Lynd LD, Sandford AJ, Kelly EM, Pare PD, Bai TR, Fitzgerald JM, Anis AH.
Reconcilable Differences: A Cross-sectional Study of the Relationship Between Socioeconomic Status and the Magnitude of Short-Acting {beta}-Agonist Use in Asthma. Chest. 126(4):1161-1168. 2004 77) Zheng X, Zhou D, Seow CY and Bai TR. Cardiotrophin-1 alters airway smooth
muscle structure and mechanical properties in airway explants. Am J Physiol Lung Cell Mol Physiol. 287(6):L1165-L1171. 2004 78) Bai TR. Role of airway smooth muscle dysfunction in asthma. Journal of Asthma,
Allergy and Clinical Immunology. 24 [Suppl II]: S82-97. 2004 79) Bai TR. New approach to asthma management by adjustable dosing. Journal of
Asthma, Allergy and Clinical Immunology. 24 [Suppl II]: S121-131. 2004 80) Bai TR, Bates JH, Brusasco V, Camoretti-Mercado B, Chitano P, Deng LH, Dowell
M, Fabry B, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gunst SJ, Hai CM, Halayko AJ, Hirst SJ, James AL, Janssen LJ, Jones KA, King GG, Lakser OJ, Lambert RK, Lauzon AM, Lutchen KR, Maksym GN, Meiss RA, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Pare PD, Schellenberg RR, Seow CY, Sieck GC, Smith PG, Smolensky AV, Solway J, Stephens NL, Stewart AG, Tang DD, Wang L. On the terminology for describing the length-force relationship and its changes in airway smooth muscle. J Appl Physiol. 97(6):2029-2034. 2004 81) Davidson W, Bai TR. Lung structural changes in chronic obstructive pulmonary
diseases. Curr Drug Targets Inflamm Allergy. 4:643-649. 2005 82) Bai TR, Knight DA. Structural changes in the airways in asthma: observations and
consequences. Clin Sci (Lond). 108(6):463-477. 2005 83) Phillips P, Bonner S, Gataric N, Bai TR, Wilcox P, Hogg R, O'Shaughnessy M,
Montaner J. Nontuberculous Mycobacterial Immune Reconstitution Syndrome in HIV-Infected Patients: Spectrum of Disease and Long-Term Follow-Up. Clin Infect Dis. 41(10):1483-1497. 2005 84) Ernst P, McIvor A, Ducharme FM, Boulet LP, FitzGerald M, Chapman KR, Bai TR;
Canadian Asthma Guideline Group. Safety and effectiveness of long-acting inhaled beta-agonist bronchodilators when taken with inhaled corticosteroids. Ann Intern Med. 145(9):692-4. Review. 2006 85) McWhinnie R, Pechkovsky DV, Zhou D, Lane D, Halayko AJ, Knight DA, Bai TR.
Endothelin-1 induces hypertrophy and inhibits apoptosis in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 292:L278-L286. 2007 86) An SS, Bai TR, Bates JH, Black JL, Brown RH, Brusasco V, Chitano P, Deng L,
Dowell M, Eidelman DH, Fabry B, Fairbank NJ, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gosens R, Gunst SJ, Halayko AJ, Ingram RH, Irvin CG, James AL, Janssen LJ, King GG, Knight DA, Lauzon AM, Lakser OJ, Ludwig MS, Lutchen KR, Maksym GN, Martin JG, Mauad T, McParland BE, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Pare PD, Pellegrino R, Sanderson MJ, Schellenberg RR, Seow CY, Silveira PS, Smith PG, Solway J, Stephens NL, Sterk PJ, Stewart AG, Tang DD, Tepper RS, Tran T, Wang L. Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. Eur Respir J. 29:834-60, 2007 87) Bai TR, Vonk JM, Postma DS, Boezen HM. Severe exacerbations predict excess
lung function decline in asthma. Eur Respir J. 30:452-6. 2007 88) Ernst P, Franssen E, Chan CK, Okell M, O'Byrne P, Bai TR. Predictors of a more
favourable response to combined therapy with salmeterol and fluticasone as initial maintenance therapy in asthma. Respir Med. 102:77-81. 2008 89) Sears MR, Boulet LP, Laviolette M, Fitzgerald JM, Bai TR, Kaplan A, Smiljanic-
Georgijev N, Lee JS. Budesonide/formoterol maintenance and reliever therapy: impact on airway inflammation in asthma. Eur Respir J 2008. (Published on January 23, 2008 as doi: 10.1183/09031936.00104007)
Submitted/In preparation

1. James A, Green F, Abramson M, Bai TR, Dolhnikoff M, Mauad T, McKay K, Elliot J. Airway basement membrane perimeter distensibility and airway smooth muscle area asthma. Submitted to Journal of Applied Physiology February 12, 2008. 2. Relationship between bronchial carcinoids and airways hyperresponsiveness. 3. Effect of exacerbations on FEV1 decline in asthma. 4. The Clinical Utility of Induced Sputum in the Investigation of Chronic Cough: A Pilot Randomized Trial. Warren Davidson, Pearce Wilcox, Tony Bai.
1. Bai TR, Rabinovitch BJ, Pardy RL. The limits to sustained hypernea. Am Rev
Respir Dis 1983; 127 (4):A257. Presented at ATS meeting, 1983. 2. Hasnain SN, Rabinovitch BJ, Bai TR, Milic-Emili J, Pardy RL. Inspiratory pleural
pressure-time index correlates with inspiratory muscle power during heavy exercise in normal man. Clin Invest Med 1983; 6 (2):76. Presented at RCP meeting, 1983. 3. Shore S, Bai TR, Martin JG. Effects of atropine on histamine-induced
bronchoconstriction in the anaesthetized vagotomized dog. Am Rev Respir Dis 129 (4):243, 1984. Presented at ATS meeting, 1984. 4. Bai TR, Macklem PT, Martin JG. The effects of partial or complete
vagosympathetic section on induced bronchoconstriction in the cat. Am Rev Respir Dis (4):263, 1984. Presented at ATS meeting, 1984. 5. Bai TR, Macklem PT, Martin JG. The nonadrenergic, noncholinergic inhibitory
system and bronchial responsiveness. Aust NZJ Med 14(6):955, 1984. Presented at TSANZ meeting, 1984. 6. Jagusch MF, Bai TR. The clinical course of idiopathic chronic eosinophilic
pneumonia. NZ Med J 99:163, 1986. Presented at TSANZ meeting, 1986. 7. Isaacs RD, Wells A, Wattie WJ, Bai TR, Rea HH. Massive hemoptysis as a
consequence of radiation induced neovascularization, treated by bronchial artery embolization. NZ Med J 1986; 99:164, 1986. Presented at TSANZ meeting, 1986. 8. Bai TR, Martin JG. Effects of indomethacin and ascorbic acid on histamine induced
bronchoconstriction in normal subjects. NZ Med J 99:163, 1986. Presented at TSANZ meeting, 1986. 9. Bai TR, Whitlock RML, Harris EA. Clinical experience with a modified carbon
monoxide removal fraction. Am Rev Respir Dis 133 (4):A384, 1986. 10. Veale AV, Bai TR, Jagusch MF, Smith W. Amiodarone pulmonary toxicity. NZ Med
J 100:387, 1987. Presented at TSANZ meeting, 1987. 11. Cutten AEC, Bai TR, Hasnain SM, McKay J. Allergic responses to basidiospores -
Ganoderma Mastoporum. Aust Microbiologist 8 (2):133, 1987. Presented at Aust Soc Microbiol meeting, 1987. 12. Bai TR, Lam R, Prasad FWF. Functional characteristics of post mortem human
tracheal smooth muscle. NZ Med J 101:579, 1988. Presented at TSANZ meeting, 1988. 13. Bai TR. Airway smooth muscle abnormalities in fatal asthma. Am Rev Respir Dis 4
(2):A258, 1989. Presented at ATS meeting, 1989. 14. Bai TR. Airway smooth muscle abnormalities in fatal asthma: a comparison of
tracheal and bronchial smooth muscle. Aust NZ J Med 19 (5):664, 1989. Presented at TSANZ meeting, 1989. 15. Bai TR. Effects of epithelial removal on responsiveness in human tracheal smooth
muscle. Am Rev Respir Dis 141 (4):A289, 1990. Presented at ATS meeting, 1990. 16. Bai TR, Mak JC, Barnes PJ. A comparison of beta-adrenergic receptor density and
in vitro relaxant responses to isoproterenol in asthmatic smooth muscle. Am Rev Respir Dis 143 (4):A748, 1991. Presented at ATS meeting, 1991. 17. Bai TR, Zhong J, Hayashi S. Detection of vasoactive intestinal peptide (VIP) mRNA
in proximal airway of postmortem human lung. FASEB J 5 (6):A1055, 1991. Presented at FASEB meeting, 1991. 18. Okazawa M, Bai TR, Wiggs B, Paré PD. Parenchymal interdependence and airway
smooth muscle (ASM) shortening in excised canine lung lobes. Am Rev Respir Dis 143 (4):A559, 1991. Presented at ATS meeting, 1991. 19. Robinson PJ, Bai TR, Paré PD, Schellenberg RR. Isoproterenol relaxation
properties of isolated tracheal preparation from hyperresponsiveness guinea pigs. Clin Invest Med 14 (4A):A6, 1991. Presented at RCP/CTS meeting, 1991. 20. Bai TR, Paré PD, Schellenberg RR. Effects of peptidases and inhibitors of nitric
oxide (NO) synthase on the non-adrenergic, non-cholinergic inhibitory neural response (NANCi) in human and guinea pig airway smooth muscle. Clin Invest Med 14 (4A):A115, 1991. Presented at RCP/CTS meeting, 1991. 21. Kuwano K, Bosken C, Bai TR, Wiggs B, Hogg JC. Morphometric dimensions of
small airways in asthma and COPD. Clin Invest Med 14 (4A):A115, 1991. Presented at RCP/CTS meeting, 1991. 22. Lambert R, Kuwano K, Bai TR, Wiggs B, Hogg JC and Paré PD. A model of the
morphologic and mechanical determinants of maximal airway narrowing. Am Rev Respir Dis 145 (4):A386, 1992. Presented at ATS meeting, 1992. 23. Bai TR, Hards J, Paré PD. A semi-quantitative comparison of vasoactive intestinal
peptide (VIP-immunoreactive) nerve fibre density in normal and asthmatic tracheal and large bronchial smooth muscle. Am Rev Respir Dis 145 (4):A259, 1992. Presented at ATS meeting, 1992. 24. Lilly CM, Bai TR, Shore SA, Sugarbaker D, Drazen JM. Neuropeptide-like
immunoreactivity (LI) is greater in human trachea than lung parenchyma. Am Rev Respir Dis 145 (4):A681, 1992. Presented at ATS meeting, 1992. 25. Child S, Zhou D, Aubert J-D, Bondy G, Hayashi S, Bai TR. β2 adrenergic receptor
gene expression is increased in lung parenchyma in asthma. Am Rev Respir Dis 145 (4):A830, 1992. Presented at ATS meeting, 1992. 26. Bai TR, Bramley AM, Schellenberg RR, Paré PD. Nitric oxide mediates non-
adrenergic non-cholinergic inhibitory neural responses in human bronchial smooth muscle. Am Rev Respir Dis 145 (4):A383, 1992. Presented at ATS meeting, 1992. 27. Aubert J-D, Dalal B, Bai TR, Hayashi S, Hogg JC. Expression of transforming
growth factor β-1 mRNA and protein in human lungs with asthma or chronic airflow obstruction. Clin Invest Med 1992. Presented at ATS meeting, 1992. 28. Bai TR, Zhou D, Weir T, Aubert J-D, Hayashi S, Bondy G, Strader C, Fong T.
Regional distribution and relative expression of β2 adrenergic receptor (β2AR) and tachykinin receptor (NK1 and NK2) mRNA in human bronchi and peripheral lung. Am Rev Respir Dis 147 (4):A275, 1993. Presented at ATS meeting, 1993. 29. Bai TR, Weir T, Aubert J-D, Hegele R, Hayashi S, Strader C, Fong T. Detection of
substance P receptor (NK1) mRNA by in vivo hybridization in human trachea and peripheral lung. FASEB J 7 (4,II):A506, 1993. Presented at FASEB meeting, 1993. 30. Aubert J-D, Hards J, Bai TR, Hayashi S, Paré PD, Hogg JC. mRNA expression
and immunolocalization of platelet-derived growth factor receptor-β and its ligand in airways from asthmatics, COPD and control subjects. Am Rev Respir Dis 147 (4):A784, 1993. Presented at ATS meeting, 1993. 31. Baile EM, Ernest D, Verburgt LM, Bai TR, Paré PD. Endogenous nitric oxide
influences baseline bronchial blood flow in sheep. Am Rev Respir Dis 147 (4):A659, 1993. Presented at ATS meeting, 1993. 32. Wang Z, Paré PD, Bai TR. Effect of chronic infusion of substance P (SP) on in vivo
airway responsiveness in guinea pigs. FASEB J 7 (4,II):A505, 1993. Presented at FASEB, 1993. 33. Bondy GP, Granleese S, Bicknell S, Aubert J-D, Hogg JC, Bai TR. RNA expression
and localization of the nuclear hormone receptor ST-590 (NUR77/NGF-B/N10) in human lung. J Cellular Biochem Suppl 17A, 152, 1993. Presented at Western Biochem Society, 1993. 34. Wang ZL, Paré PD, Bai TR. Effect of β2 adrenergic receptor (β2AR) agonists on
airway responsiveness in guinea pigs. Clin Invest Med 16 (Supp B):B127, 1993. Presented at RCP/CTS meeting, 1993. 35. Canadian Multicentre Study Group. A multi-centre clinical trial to compare the safety profiles of fenoterol MDI and albuterol MDI in acute severe adult asthmatics treated in the emergency room. Am Rev Respir Dis 147 (4):A57, 1993. Presented at ATS, 1993. 36. Bai TR, Zhou D, Walker B. Regulation of substance P receptor (NK1R) gene
expression in astrocytoma cells. The Physiologist 36 (5):A14, 1993. Presented at APS meeting, 1993. 37. Lilly CM, Bai TR, Hall AE, Shore SA, Drazen JM. Neuropeptide-like
immunoreactivity in human lungs at autopsy. Am J Respir Crit Care Med 149 (4):A889, 1994. Presented at ATS meeting, 1994. 38. Bai TR, D Zhou, T Weir, S Hayashi, T Fong. Expression of tachykinin receptors in
inflammatory airway disorders. Am J Respir Crit Care Med 149 (4):A859, 1994. Presented at ATS, 1994. 39. Wang Z-L, Bramley AM, McNamara A, Paré PD, Bai TR. Chronic fenoterol
exposure increases in vivo and in vitro airway responses in guinea pigs. Am J Respir Crit Care Med 149 (4):A768, 1994. Presented at ATS, 1994. 40. Bai TR, Wang Z-L, Walker B, Weir T, Roberts C, Okazawa M, Paré PD. Effect of
chronic antigen and fenoterol exposure on small airway dimensions and cell proliferation in guinea pigs. Am J Respir Crit Care Med 149 (4):A767, 1994. Presented at ATS, 1994. 41. Turner MO, Crump S, Contreras GR, Vedal S, Bai TR, FitzGerald JM. A
prospective evaluation of risk factors for near fatal asthma (NFA):clinical characteristics. Am J Respir Crit Care Med 149 (4):A192, 1994. Presented at ATS, 1994. 42. Bai TR, Weir T, Walker B, Salvatore CA, Johnson RG, Jacobson MA. Localization
of adenosine A3 receptors by in situ hybridization in human lung. FASEB J 8 (5):A800, 1994. Presented at FASEB 1994. 43. Bai TR, Weir T, Walker BM, Salvatore CA, Johnson RG, Jacobson MA.
Comparison and localization of adenosine A3 receptor expression in normal and asthmatic lung. Drug Development Research 31 (4):244, 1994. Presented at 5th International Adenosine meeting, 1994. 44. Sasaki F, March R, Verburgt LM, Bai TR, Paré PD, Baile EM. Endogenous nitric
oxide influences acetylcholine-induced bronchovascular dilation in sheep. Am J Respir Crit Care Med 149 (4):A539, 1994. Presented at ATS, 1994. 45. Canadian Combined Study Group. A study of the efficacy and safety of nebulization therapy combining ipratropium bromide 0.5 mg with salbutamol sulphate 3.0 mg versrus salbutamol sulphate 3.0 mg alone in acute asthma. Am J Respir Crit Care Med 149 (4):A190, 1994. Presented at ATS, 1994. 46. Bai TR, Wang Z-L, Walker BM, Paré PD. Chronic allergic inflammation induces
replication of airway smooth muscle cells in vivo in guinea pigs. Chest107:93S, 1995. Presented at Aspen Lung Conference, 1994. 47. Lau E, Mckay KO, Paré PD, Bai TR. Prior neuropeptide depletion does not prevent
airway smooth muscle proliferation induced by antigen exposure in vivo. Am J Respir Crit Care Med 151 (4):A47, 1995. 48. Bai TR, Zhou D. Substance P (SP) induces proliferation of Human Lung
Fibroblasts. Am J Respir Crit Care Med 151 (4):A370, 1995. 49. Bai TR, Tan WC, Staples C, Chan N, Hegele R, Hogg JC. Family clustering of
alveolar microlithiasis. Am J Respir Crit Care Med 151:A203, 1995. 50. McKay KO, Bai TR, Schellenberg RRS. Airway smooth muscle in rabbit airway
explants is unaffected by histamine. Am J Respir Crit Care Med 151:A111, 1995. 51. Baile EM, Sasaki F, Bai TR, Paré PD. Contrast- induced bronchial vascular dilation
is attenuated by N omega nitro-l-arginine. Am J Respir Crit Care Med 151:A622, 1995. 52. Knight DA, Bai TR, Weir T, Salvatore CA, Jacobson MA, Walker BAM. Expression
and function of Adenosine A3 receptors in Human Lung Tissue. Am J Respir Crit Care Med 153: IA645, 1996. 53. Knight DA, Zhou D, Weir T, Bai TR. Determination of predominant cell types
expressing tachykinin receptors in human lung. Am J Respir Crit Care Med A161, 1996. 54. Bai TR, McKay K, Wiggs B, Knight DA. Effects of chronic β2-agonist exposure on
airway smooth muscle contractility: comparison of fenoterol with formoterol. Am J Respir Crit Care Med 153: A629, 1996. 55. Hamid Q, Minshall E, Bai TR, Hegele, RG, Hogg J. Th2-type cytokines in small
airways of asthmatic lungs. J Allergy Clin Immunol .Presented at AAAAI/AAI/CIS Joint Meeting, 1997 56. Weir TD, Malleck N, Sandford AJ, Bai TR, Awadh N, FitzGerald JM, Liggett SB,
Paré PD. Genetic polymorphisms of the β2 -adrenergic receptor in fatal and near-fatal asthma. Am J Respir Crit Care Med 155:A256, 1997. 57. Knight DA, McKay KO, Zhou D, Schellenberg RR, Bai TR. Leukemia inhibitory
factor (LIF) enhances tachykinin-induced airway smooth muscle contraction and expression of NK-2 receptor mRNA. Am J Respir Crit Care Med 155:A484, 1997. 58. Knight DA, Lydell CP, Zhou D, Schellenberg RR, Bai TR. Distribution and
modulation of leukemia inhibitory factor (LIF) and LIF receptor (LIF-R) in human airway cells. Am J Respir Crit Care Med 155:A204, 1997. 59. Bai TR, McKay KO, Knight DA. Induction of Th2-type immune responses as a
mechanism for airway abnormalities induced by chronic administration of β2 adrenoceptor agonists. Am J Respir Crit Care Med 155; A208; 1997. 60. Bai TR, Cooper J, Weir T, Wiggs B, Koelmeyer T. Airway wall thickening is greater
in middle-aged compared with young adults with fatal asthma. Am J Respir Crit Care Med 155:A503, 1997. 61. Knight DA, Bai TR, Rocchini C, Jacobson MA, Walker BAM. Activation of
adenosine A3 receptors inhibits platelet-activating factor induced migration of human eosinophils. Presented at Purines 96 Milan 62. Boldt MJ Bai TR. Usefulness of lactate dehydrogenase in the diagnosis of
pneumocystis carinii pneumonia. Clin Invest Med 1996. Presented at Royal college meeting, Halifax 63. Fitzgerald JM, Grunfeld A, Bai TR, Shragge DL, Haddon JMF, Jennings B High
dose inhaled budesonide versus prednisone in patients with acute asthma discharged from the emergency room. Am J Respir Crit Care Med 155:A 532 1997. 64. Yasruel Z, Minshall E, Bai TR, Hegele, RG, Hogg J. Hamid Q Th2-type cytokines
in small airways of asthmatic lungs. Am J Respir Crit Care Med 155:A680, 1997. 65. Chagani T, Paré PD, Weir T, Bai TR, James A, Awadh N, Fitzgerald MF, Sanford A.
TNF and IL4 gene promoter polymorphisms in asthma. Am J Respir Crit Care Med 157: A875, 1998. 66. Zheng X, Knight D, Bai TR. Modulation of SP-induced eosinophil chemotaxis by
LIF. Am J Respir Crit Care Med 157:A389, 1998. 67. Knight DA, Zhou D, Bai TR. LIF induces SP release and increases NK-1R gene
expression in tracheal explants. Am J Respir Crit Care Med 157:A490, 1998. 68. Idrees M, king, G, Cockcroft D, Bai TR, Anis A, Wong S, Paré PD. An asthma
severity score not confounded by control. Am J Respir Crit Care Med 157:A633, 1998. 69. Zheng X, Zhou D, Bai TR Enhanced LIF production from human eosinophils in
atopic subjects. Am J Respir Crit Care Med 1999: 159: A92 70. Beaudin B, Bai TR, Bates J, Clark L et al. An evaluation of the needs of people
living with asthma and an assessment of how well those needs are being met. 4th Conference of the Canadian network for asthma care. Halifax 1999 71. Zhou, D, Zheng X, Bai TR. Both nerve growth factor and Leukemia Inhibitory factor
augment substance P release in airway explants. Am J Respir Crit Care Med 2000; 161: A839 72. Bai TR and Weir TW. Dry airways in fatal asthma are a rare finding. Am J Respir
73. Kuyper LM, Paré PD, Hogg JC, Ionescu D, Lambert R, Bai TR. Characterisation of
lumenal contents in fatal asthma. Am J Respir Crit Care Med 2001; 163: A757 74. Zheng X, Karsan A, Duronio V, Bai TR, Schellenberg RR. Interleukin-3 inhibits
apoptosis of human basophils by activation of phosphatidylinositol 3-kinase; role of NF-KB-dependent and independent pathways. Am J Respir Crit Care Med 2001; 163: A322 75. Zheng X, Davidson A, Bai TR, Schellenberg RR. Tryptase regulates human airway
smooth muscle contraction and apoptosis. Am J Respir Crit Care Med 2001; 163: A271 76. Zheng X, Zhou D, Bai TR. CT-1 alters airway smooth muscle structure and
mechanical properties. Am J Respir Crit Care Med 2002; 165: A118 77. Aboussafy D, Vaughn R, Bai TR, Fitzgerald M. Near fatal asthma: distinguishing
psychological characteristics. Am J Respir Crit Care Med 2002; 165: A433 78. Bai TR, Zhou D, Beaudin B, Chong G, Ensom M. Are peri-menstrual asthma
symptoms related to worsening airway inflammation? Am J Respir Crit Care Med 2002; 165: A560 79. Ensom MHH, Chong G, Beaudin B, Shalansky, Bai TR. Double-Blind, Randomized,
Placebo-Controlled, Crossover Study of Estradiol in Premenstrual Asthma. Pharmacotherapy 2002;22: 1371-2 80. Bai TR, Zhou D, Zheng X. Morphologic basis of airways hyperresponsivess
associated with bronchial carcinoid tumors. Am J Respir Crit Care Med 2003. 167(7): A77 81. Zheng X, Zhou D, McWhinnie R, Bai TR. Endothelin-1 (ET-1) Reduces Serum
Deprivation-Induced Apoptosis in Human Airway Smooth Muscle Cells (HASMC) and Up-Regulates Cardiotrophin-1 (CT-1) Protein Synthesis. Presented at the 2004 International Conference, American Thoracic Society, Orlando Florida, May 2004. 82. McWhinnie R, Zhou D, Zheng X, Knight DA, Bai TR. Endothelin-1 induces
hypertrophy of human airway smooth muscle cells via a STAT-3 dependent pathway. Proceedings of the American Thoracic Society. 2:A 340. 2005 83. Davidson WJ, Sin D, Wilcox PG, Attridge S, Bai TR. A comparison of the Leicester
Cough Questionnaire with the St. George’s Respiratory Questionnaire in the evaluation of treatment response in patients with chronic cough. Proceedings of the American Thoracic Society. 2: A 323. 2005 84. Davidson WJ, Wilcox P, Bai TR. Clinical utility of induced sputum in the
investigation of chronic cough: a pilot randomized trial. Proceedings of the American Thoracic Society International Conference, San Diego, CA. Vol. 3: A374 May 2006 85. James J, Carroll N, Abramson M, McKay K, Mauad T, Bai T, Green F, Elliot J.
Multi-Centre Study of Airway Smooth Muscle. Proceedings of the American Thoracic Society International Conference, San Diego, CA. Vol. 3: A260 May 2006 86. Bai TR, Vonk JM, Postma DS, Boezen HM. Do exacerbations contribute to FEV1
decline in asthma? Presented at the American Thoracic Society International Conference, San Diego, CA. Vol. 3: A474 May 2006 87. Singhera GK, Allahverdian S, Knight DA, Hegele R, Van Eeden S, Bai TR,
Dorscheid DR. Bronchial Immune Barrier and Epithelial Repair Alters in Response to RSV and Particulate Air Pollution (PM10). ATS International Conference, May 18-23, 2007. Am J Respir Crit Care Med 175:A475, 2007 88. Hackett T-L, Shaheen F, Singhera G, Dorscheid D, Bai TR, Van Eeden S, Hegele
R, Knight DA. Characterization of Bronchial Epithelial Side Population (SP) Cells: Progenitors of Multiple Cell Types. ATS International Conference, May 18-23, 2007. Am J Respir Crit Care Med 175:A979, 2007 89. Hackett T-L, Shaheen F, Jacoby D, Dorscheid D, Bai TR, Knight DA. Identification
of Isolectin B4+/ΔNp63+ as Resident Epithelial Progenitor Cells in Human Airways: Up Regulation in Asthma. ATS International Conference, May 18-23, 2007. Am J Respir Crit Care Med 175:A980, 2007 90. Cruz Sanchez TM, Haddrell A, Bai TR, Dorscheid D, Knight DA, van Eeden S, and
Agnes G. Comparative Analysis of Asthmatic vs Normal Bronchial Epithelial Cellular Responses to Incubation with Ambient Particular Matter and/or Respiratory Syncytial Virus. ATS International Conference, May 18-23, 2007. Am J Respir Crit Care Med 175:A475, 2007.
INVITED PUBLICATIONS

(a) Journals
1. Richards G, Bai TR. Alpha-one-Antitrypsin: A protein with many implications.
2. Bai TR. Management of the Elderly Asthmatic. New Ethicals Feb: 93-103, 1987.
3. Bai TR. Management of chronic asthma. Medicine North America 6:3708-3715,
4. Bai TR. Airway abnormalities in asthma. Asthma Digest 1:20-21, 1992.
5. Bai TR. Action plans for asthma. Are they necessary? Airwaves (Can Thoracic
6. Bai TR. Drugs and the Lung (review). Quarterly Review of Biology 70 (2):249,
7. Davidson W and Bai TR. Asthma: Clearing the Way. Can J Diag. November, pp

BOOKS
(a) Authored
1. The regulation of the airway response to bronchoconstrictor drugs. University of
Otago Library, Dunedin, N.Z., 245 pages, 1987 (thesis).
(c) Chapters
1. Bai TR. Pneumonia. In: The Disease Index, Medical Publishing Company,
Auckland, New Zealand, pp. 367-69, 1989. 2. Bai TR and Belvisi MG. I-NANC Innervation: Role of nitric oxide. In: Airway
Smooth Muscle, A Reference Source (Vol. 1). Raeburn D, Giembycz MA, Eds. pp 157-189, Birkhauser Verlag AG, Basel, 1994. 3. Martin JG and Bai TR. In vivo models of airway smooth muscle growth. In: Airway
wall remodelling in asthma. Stewart AG ed. CRC Press, Boca Raton, FL. Pp 213-226. 1996 4. Bai TR. Adrenergic Receptor Agonists and antagonists. In: Allergy and Allergic
Diseases. Kay AB, ed. Blackwell Science, Oxford. pp 564-579, 1996 5. Bai TR. Chronic obstructive pulmonary disease. In: Therapeutic Choices, 1st
edition, Gray J, editor in chief, pp 260-267, Canadian Pharmaceutical Association 1995; 2nd edition 1997, 3rd edition 1999 6. Bai TR. Cough. In: Therapeutic Choices, Gray J, ed. pp 708-713, Canadian
Pharmaceutical Association 1995.2nd edition 1997, 3rd edition 1999 7. Bai TR. Asthma - the role of beta adrenergic receptors. In: Asthma. Barnes PJ,
Woolcock A, Grunstein M, Leff, A, Eds. Raven Press, NY. 1997; 985-995 8. Jacobson Ma and Bai TR. The role of adenosine in asthma. In: Purinergic
Approaches in Experimental Therapeutics. Jacobson K, Jarvis M, Eds. John Wiley & Sons, NY. chapter 17; pp 315-331, 1997 . 9. Paré PD, Bai TR, Roberts CR. The structural and functional consequences of
chronic allergic inflammation of the airways. In : The rising trends in asthma. Ciba Foundation Symposium 206. Holgate S, Ed. John Wiley and sons, Chichester, UK 1997: 71-89 10. Paré PD, Sandford AJ, Bai TR. Pathophysiological processes in COPD. In: The
role of anti-cholinergics in COPD and chronic asthma. Price AH Editor. Gardiner Caldwell , Macclesfield, UK, pp 19-30.1997 11. Bai TR Roberts CR, Paré PD. Airway remodelling. In: Asthma: Basic mechanisms
and clinical management. Rodgers, I; Barnes PJ Eds (Third Edition). Academic Press, London, UK Chapter 26;pp 476-486. 1998 12. Bai TR and Knight DA. Role of the nervous system in airway remodelling. In :
Airway Remodelling. Howarth P and Pauwels R, Eds. Lung Biology in Health and Disease, Vol 109;pp 147-165, Marcel Dekker Inc. New York, 2000 13. Bai TR. Mechanisms of action of Beta Adrenergic Agonists and Short Acting B2
therapy. In: Evidence Based Asthma Management. Fitzgerald MF, Ernest P, Boulet LP, O’Byrne P, Eds. B.C. Decker, Hamilton, Ont. Chap 12: 137-149. 2001 14. Bai TR, Kenney A and Van Gorder B. Asthma. pp 33-45. In: Respiratory Disease
15. Bai TR. Adrenergic agonists and antagonists. In: Allergy and Allergic Diseases. Second Edition. Editors: Kay, AB, Bousquet J, Holt P, Kaplan AP. Wiley-Blackwell, in press 2008.
OTHER WORKS

1. "Asthma. A Self- Management Handbook." Prepared for employees of London
2. “Diagnosis and management of asthma“. B Winsby, G Ward, TR Bai, W Edmonds,
G McCauley. BCMA / Ministry of Health BC, 2003 3. “Future Asthma Therapies”. In Asthma: A Specialist Education Program -Canadian
INVITED PRESENTATIONS
1. 1988 September - Royal Australasian College of Physicians, Auckland - "Persistent
2. 1991 September - Royal College of Physicians and Surgeons of Canada/Canadian Thoracic Society Annual Meeting, Quebec City - "The β2 adrenergic receptor in asthma" 3. 1993 September - Royal College of Physicians and Surgeons of Canada/Canadian Thoracic Society, Vancouver - "Action plans in the management of asthma" 4. 1993 February - Respiratory Network of centres of Excellence Workshop, Montreal " Molecular Biology of Tachykinin Receptors" 5. 1995 February - Respiratory Network of centres of Excellence Workshop, Montreal "Allergic basis of Airway Hyperresponsiveness" 6. 1995 Nov - University of Miami CME course on Asthma management - "Morphologic Basis of Airflow Obstruction" 7. 1995 October - Dutch Federation of Scientific Societies, Dutch Asthma Federation, Asthma Symposium, Amersfoort, The Netherlands "Structural Changes of Airways: functional impact and prognostic value" 8. 1996 February - Respiratory Network of centres of Excellence Workshop, Montreal 9. 1996 March - American Academy of Allergy, Asthma and Immunology, New Orleans, Symposium on Neural Influences on the Airways "Regulation of Receptor expression in asthma" 10. 1996 March - Respiratory Network of Centres of Excellence Workshop, Quebec City, "Animal Models of airway remodelling" 11. 1996 May - American Thoracic Society, New Orleans, "Beta adrenergic responses 12. 1997 May- American Thoracic Society, San Francisco. Co-chair, Symposium on 13. 1997 Nov 7 Quaeritur Symposium VIII (an international, predominantly European faculty hosting a series of meetings on asthma), London, UK. Symposium Chairman, Steven Holgate. Topic: the chronicity of asthma 14. 1998 Oct 30. Quaeritur Symposium IX, London UK, “Asthma Exacerbations”, 15. 1998 Oct 14, University of Gothenburg, Sweden; Symposium on airway remodelling. ”Role of nerves in of airway remodelling”. 16. 1999 October, European Respiratory Society Annual meeting, Madrid - "Interactions between the Immune and Nervous Systems in the Lung" 17. 2000 March 6th – American Academy of Allergy, Asthma and Immunology annual Meeting, San Diego –“Functional consequences of airway remodelling” 18. 2000 November Canadian COPD Alliance “ A stepwise approach to 19. 2001 December 1 Canadian Network for Asthma Care, AGM Toronto “ Airway 20. 2002 April 19 Alberta Lung Association annual conference [Banff] (1) Efficacy & safety of Long acting b agonists (2) Functional consequences of airway remodelling 21. 2002 CTS/ACCP November 2 San Diego “Action plans for asthma” 22. 2003 ERS Vienna, September 29 “Adjustable asthma therapy” 23. October 23 2nd annual Respiratory Sciences Workshop - Miami – “Smooth Muscle 24. Korean Academy of Asthma and Allergy Congress annual meeting , Seoul, Korea, May 29 2004 - “Role of smooth muscle in asthma” 25. The University of Groningen, Netherlands - “Airway remodelling”, September 1 2004 26. The University of Leiden, Netherlands - "Role of airway smooth muscle in asthma - 27. European Respiratory Society Annual Meeting Copenhagen. "Contractility of bronchial smooth muscle and changes during disease", September 18 2005

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