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Chapter 13: Skin The GHT Formulary applies to the treatment of adults only 13.1 Management of skin conditions
● Please refer to the BNF for information regarding vehicles, excipients, sensitisation and
suitable quantities for prescribing. 13.2 Emollient and barrier preparations How to locate a drug in Hospital 13.2.1 Emollients Emollient soap substitutes
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Emollients containing urea Emollients containing antimicrobials 13.2.1.1 Emollient bath additives Emollient bath additives with antimicrobials 13.2.2 Barrier Preparations
Cavilon® no-sting barrier film applicators 1mL & 3mL - supplied by stores not pharmacy
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Siopel ® cream - Not to be used on broken skin
Zinc and castor oil ointment – zinc preparations are restricted to use by
the dermatologists as Cavilon® and Siopel ® are the products in the Trust’s Wound Care Guidelines. 13.3 Topical local anaesthetics and antipruritics
Menthol in Aqueous cream 0.5% & 1% - are only available as ‘special’ preparations (i.e. not proprietary products). These preparations are not
cost-effective in primary care and there may be a significant delay in obtaining such preparations.
Doxepin Hydrochloride 5% cream (Xepin®) – for small areas only.
Restricted to dermatology. Doxepin cream can cause drowsiness that may affect skilled tasks and there may be a risk of sensitisation. 13.4 Topical corticosteroids
Suitable quantities of corticosteroid preparations to be prescribed for specific areas of the body
Amount per application Amount of one leg grams per
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Hydrocortisone 0.1, 0.5, 1.0 and 2.5% cream/ointment
Fluocinolone 0.0025% (Synalar 1 in 10 Dilution®) cream
Moderate
Clobetasone butyrate 0.05% (Eumovate®) cream/ointment
Betamethasone valerate 0.025% (Betnovate RD®) cream/ointment
Fludroxycortide 4 micrograms/cm2 (Haelan®) tape
Fluocinolone 0.00625% (Synalar 1 in 4 Dilution®) cream/ointment
Beclometasone dipropionate 0.025% (Propaderm®) cream/ointment
Betamethasone valerate 0.1% (Betnovate®)cream/ointment/lotion
Betamethasone dipropionate 0.05% with salicylic acid 3% (Diprosalic®) ointment
Diflucortolone 0.1% (Nerisone®) oily cream
Fluocinolone 0.025% (Synalar®) cream/ointment
Mometasone furoate 0.1% (Elocon®) cream/ointment
Very Potent
Clobetasol propionate 0.05% (Dermovate®) cream/ointment
Diflucortolone 0.3% (Nerisone Forte®) oily cream
Topical Steroids with antimicrobials
Hydrocortisone 1% and clioquinol 3% (Vioform–Hydrocortisone®) cream/ointment
Hydrocortisone 1% and clotrimazole 1% (Canesten HC®)
Hydrocortisone 1% and fusidic acid 2% (Fucidin H®) cream/ointment
Hydrocortisone 1% and miconazole 2% (Daktacort®) cream/ointment
Hydrocortisone 0.5% (cream), 1% (ointment), nystatin 100,000 units/g and chlorhexidine 1% (Nystaform HC®)
Hydrocortisone 0.5%, nystatin 100,000 units/g, benzalkonium chloride solution 0.2% and dimeticone ‘350’ 10% (Timodine®) cream
Moderate
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Clobetasone butyrate 0.05%,oxytetracycline 3% & nystatin 100,000 units/g (Trimovate®) cream
Betamethasone 0.1% and clioquinol 3% (Betnovate C®) cream/ointment
Betamethasone dipropionate 0.064% and clotrimazole 1% (Lotriderm®) cream
Betamethasone 0.1% and fusidic acid 2% (FuciBET®) cream
Betamethasone 0.1% and neomycin 0.5% (Betnovate N®) cream /ointment
Hydrocortisone butyrate 0.1% and chlorquinaldol 3% (Locoid C®) cream/ ointment
Triamcinolone 0.1% and chlortetracycline 3% (Aureocort®) ointment
Triamcinolone 0.1%, gramicidin 0.025%, neomycin 0.25%, nystatin 100,000 units/g (Tri-Adcortyl®) cream
Very Potent
Clobetasol propionate 0.05%, neomycin sulphate 0.5% and nystatin 100,000 units/g (Dermovate NN®) cream/ointment
Compound preparations
Hydrocortisone 0.25% and crotamiton 10% (Eurax-Hydrocortisone®) cream
Moderate
Hydrocortisone 1% and urea 10% (Alphaderm®) cream
Hydrocortisone 1%, urea 10%, lactic acid 5% (Calmurid HC®) cream
Steroid scalp applications
Betamethasone 0.1% (Betacap®) scalp application, (Betnovate®) scalp application, (Bettamousse®) foam scalp application
Betamethasone 0.05% and salicyclic acid 2% (Diprosalic®) scalp application
Fluocinolone acetonide 0.025% (Synalar®) gel
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Very Potent 13.5 Preparations for Eczema and Psoriasis 13.5.1 Preparations for eczema
● Please refer to section 13.2 (emollients) and 13.4 (topical corticosteroids).
Zinc paste and ichthammol bandage – only to be applied by a Nurse skilled in
● Ichthammol cream (Hospital Formula 2%) is only available as a ‘special’ preparation (i.
e. not a proprietary product). These preparations are not cost-effective in primary care and there may be a significant delay in obtaining such preparations. 13.5.2 Preparations for psoriasis Topical preparations
● Please refer to the BNF for information regarding vitamin D and analogues.
Vitamin D and analogues
Calcipotriol with betamethasone 0.05% (Dovobet®) ointment
Calcipotriol with betamethasone 0.05% (Dovobet®) gel – body and scalp
Calcitriol 3micrograms/g (Silkis®) ointment
● Treatment with Dovobet® should be initiated by a specialist and not exceed 4 weeks.
There is no experience of repeated use. Refer to BNF for dose information. Topical retinoid
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Compound product
● Chelsea Day mix (Hospital Formula) is only available as a ‘special’ preparation (i.e. not
a proprietary product). These preparations are not cost-effective in primary care and there may be a significant delay in obtaining such preparations.
Alphosyl HC® Cream (with hydrocortisone 0.5%)
Polytar® bath emollient (contains peanut oil)
● Chelsea Night mix and Coal Tar and Salicylic Acid ointments are only available as
‘special’ preparations (i.e. not proprietary products). These preparations are not cost-effective in primary care and there may be a significant delay in obtaining such preparations. Dithranol
Dithrocream® 0.1%, 0.25%, 0.5%, 1% and 2%
Dithranol in Lassar’s Paste 0.1%, 0.25%, 0.5%, 1%,
● Dithranols in Lassar’s Paste are only available as ‘special’ preparations (i.e. not
proprietary products). These preparations are not cost-effective in primary care and there may be a significant delay in obtaining such preparations. Oral retinoids for psoriasis 13.5.3 Drugs affecting the immune response
Tacrolimus 0.03% and 0.1% (Protopic®) ointment - specialist use only
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Pimecrolimus 1% cream - specialist use only
Systemic
● Please refer to section 8.2.1 for systemic preparations
13.6 Acne and rosacea 13.6.1 Topical preparations for acne Benzoyl peroxide and azelaic acid
Benzoyl peroxide aqueous gel (PanOxyl Aquagel®) 2.5%, 5%, 10%
Benzoyl peroxide aqueous/alcoholic gel (Panoxyl® ) 5%, 10%
Benzoyl peroxide 5% and clindamycin 1% (Duac® Once Daily)
Topical antibacterials for acne
Clindamycin (aqueous)(Dalacin T® lotion)
Clindamycin (aqueous/alcoholic) (Dalacin T® solution)
Erythromycin 40mg/mL and zinc acetate 12mg/mL (Zineryt®) topical solution
Topical retinoids and related preparations for acne
● Topical retinoids are contra-indicated in pregnancy. Women of childbearing age should
take adequate contraceptive precautions.
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Tretinoin cream 0.025%, gel 0.01%, 0.025%, lotion 0.025% (Retin-A®)
Isotretinoin 0.05% and erythromycin 2% gel (Isotrexin®)
13.6.2 Oral preparations for acne Oral antibacterials for acne Hormone treatment for acne Oral retinoid for acne
Isotretinoin capsules – Hospital consultant only
13.7 Preparations for warts and calluses
Salicylic acid 16.7% and lactic acid 16.7% (Salactol®) paint
Salicylic acid 12% and lactic acid 4% (Salatac®) gel
Salicylic acid 25% and podophyllum 20% (Posalfilin®) ointment
Cantharone Plus® (Cantharidin, podophyllum resin, salicylic acid) – unlicensed
Anogenital warts
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● Ideally all patients should first receive a full genito-urinary screen at GUM but there may
be circumstances when Dermatologists may need to prescribe. 13.8 Sunscreens and camouflagers 13.8.1 Sunscreen preparations
● The following sunscreens may be prescribed for skin protection against ultraviolet
radiation in abnormal cutaneous photosensitivity resulting from genetic disorders or photodermatoses, including vitiligo and those resulting from radiotherapy; chronic or recurrent herpes simplex labialis; patients taking photosensitising drugs and patients having PUVA. Photodamage 13.9 Shampoos and other preparations for scalp and hair conditions
● Please refer to the BNF for information regarding constituents.
Polytar AF® shampoo (contains peanut oil)
Polytar Plus® liquid (contains peanut oil)
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Salicylic acid and sulphur Hospital Formula scalp cream
● Salicylic acid and sulphur Hospital Formula scalp cream is only available as a ‘special’
preparation (i.e. not a proprietary product). These preparations are not cost-effective in primary care and there may be a significant delay in obtaining such preparations. 13.10 Anti-infective skin preparations 13.10.1 Antibacterial preparations 13.10.1.1 Antibacterial preparations only used topically
Polyfax® - polymixin B sulphate and bacitracin zinc ointment
Flamazine® - silver sulfadiazine 1% cream
Flammacerium ® cream (named patients) – burns patients only
● For mupirocin nasal ointment see section 12.2.3
13.10.1.2 Antibacterial preparations also used systemically
Metronidazole 0.75% cream/gel – For malodorous tumours and skin ulcers
13.10.2 Antifungal preparations
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Amorolfine 5% (Loceryl®) nail lacquer – nail infections
Tioconazole 28% (Trosyl®) nail solution – nail infections
13.10.3 Antiviral preparations
Aciclovir 5% cream - should only be started at first sign of attack. 13.10.4 Parasiticidal preparations
● Alcoholic lotions are the treatment of choice for head lice but use aqueous solutions for
patients with severe eczema or asthma.
Malathion 0.5% aqueous liquid (Derbac M®), 0.5% alcoholic lotion
Carbaryl 1% aqueous liquid, 0.5% alcoholic lotion (Carylderm®)
Phenothrin 0.5% aqueous liquid (Full Marks®)
13.10.5 Preparations for minor cuts and abrasions Skin tissue adhesive 13.11 Skin cleansers and antiseptics
● Please refer to GHNHSFT Infection Control policy
Astringents, oxidisers and dyes
Potassium permanganate (Permitabs® 400mg)
13.12 Antiperspirants
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Aluminium chloride hexahydrate 20% (Driclor®)
13.13 Wound management products and elastic hosiery
● Please refer to the GHNHSFT Wound Management Formulary
Topical treatments for scar reduction Topical treatments for malignant and pre-malignant lesions
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A p r i l 2 1 2 0 1 0 April 21 & 22 Class 2/3 Play “The King of Ireland’s Son” Wednesday 8:30am - performance for Kinderhouse & Parents/Friends Thursday 11:30am - performance for Classes 1 -8 April 27th Class 5 Olympic Send Off – on the upper field. Class 5 Olympic Trip – No school for Class 5 on the 7th May 6, 7 & 8 Class 8 Play - “The Lion, the Wit
Biosafety Protocol Process on Liability and Redress: Food for Thought on Key Issues Paper No. 10 ONLY PERSONS OR ENTITIES DIRECTLY IMPACTED CAN BRING A CLAIM * Court proceedings on liability are not designed for voicing concerns or debating policy issues. Therefore, only a person or entity with a concrete interest may bring a liability claim. Applicable legal instr