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Clinical Trial Information: Pure Autonomic Failure
As of 7/25/12
Title: Magnetic Resonance Spectroscopy in Autonomic Failure Conditions: Pure Autonomic Failure|Multiple System Atrophy Interventions: Procedure: Magnetic Resonance Spectroscopy Imaging URL: http://ClinicalTrials.gov/show/NCT01607268 Title: Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure Conditions: Hypertension|Pure Autonomic Failure|Multiple System Atrophy Interventions: Drug: Losartan|Drug: Captopril|Drug: Placebo URL: http://ClinicalTrials.gov/show/NCT01292694 Title: The Role of Endothelin in the Supine Hypertension of Autonomic Failure Conditions: Hypertension|Pure Autonomic Failure|Multiple System Atrophy Interventions: Drug: BQ123|Drug: BQ123|Drug: Bq123|Drug: BQ123|Drug: Saline URL: http://ClinicalTrials.gov/show/NCT01119417 Title: Treatment of Supine Hypertension in Autonomic Failure Interventions: Drug: Clonidine|Drug: Nitroglycerin transdermal|Drug: Dipyridamole/ Aspirin (Aggrenox)|Drug: Desmopressin (DDAVP)|Drug: Sildenafil|Drug: Nifedipine|Drug: Hydralazine|Drug: Hydrochlorothiazide|Drug: Placebo|Drug: Bosentan|Drug: Diltiazem|Drug: Eplerenone|Drug: guanfacine|Dietary Supplement: L-arginine|Drug: captopril|Drug: carbidopa|Drug: losartan|Drug: metoprolol tartrate|Drug: nebivolol hydrochloride|Drug: prazosin hydrochloride|Drug: tamsulosin hydrochloride|Other: Head-up tilt.
URL: http://ClinicalTrials.gov/show/NCT00223717 Title: Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension Conditions: Orthostatic Hypotension|Pure Autonomic Failure|Multiple System Atrophy|Parkinson's Disease URL: http://ClinicalTrials.gov/show/NCT01316666 Title: Evaluation of Primary Chronic Autonomic Failure Conditions: Autonomic Nervous System Diseases URL: http://ClinicalTrials.gov/show/NCT00059033 Title: Treatment of Orthostatic Hypotension in Autonomic Failure Conditions: Autonomic Failure|Orthostatic Hypotension Interventions: Drug: Atomoxetine|Drug: Acarbose|Drug: Pyridostigmine Bromide|Drug: Yohimbine|Drug: Midodrine HCl|Drug: placebo|Drug: Modafinil|Drug: Octreotide|Other: water intake|Drug: Diphenhydramine Hydrochloride|Drug: Ranitidine HCL|Drug: Tranylcypromine|Drug: Ergotamine/ Caffeine|Drug: Celecoxib|Drug: Pseudoephedrine|Drug: Methylphenidate|Drug: Indomethacin|Drug: Ibuprofen|Drug: Oxymetazoline 0.05% nasal solution|Dietary Supplement: Bovril|Drug: Acetazolamide|Drug: Rivastigmine tartrate|Drug: Carbidopa/levodopa|Device: abdominal binder|Device: abdominal binder (sham) URL: http://ClinicalTrials.gov/show/NCT00223691 Title: Nebivolol in the Supine Hypertension of Autonomic Failure Conditions: Hypertension|Pure Autonomic Failure|Multiple System Atrophy Interventions: Drug: Placebo|Drug: Nebivolol 5 mg|Drug: metoprolol tartrate 50 mg|Drug: URL: http://ClinicalTrials.gov/show/NCT01044693 Title: Mechanisms Responsible for Hypoglycemia Associated Autonomic Failure Conditions: Diabetes Mel itus|Hypoglycemia|Autonomic Failure Interventions: Drug: naloxone|Dietary Supplement: fructose|Behavioral: exercise URL: http://ClinicalTrials.gov/show/NCT00678145 Title: Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mel itus Conditions: Diabetes Mel itus, Insulin-Dependent Interventions: Drug: Dehydroepiandrosterone|Drug: Placebo URL: http://ClinicalTrials.gov/show/NCT00607646 Title: The Autonomic Nervous System and Obesity Conditions: OBESITY|HYPERTENSION|PURE AUTONOMIC FAILURE|SHY-DRAGER SYNDROME Interventions: Drug: Trimethaphan|Drug: Trimethaphan|Drug: Pseudoephedrine URL: http://ClinicalTrials.gov/show/NCT00179023 Title: Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mel itus Interventions: Drug: Fludrocortisone|Drug: Dexamethasone URL: http://ClinicalTrials.gov/show/NCT00608101 Title: Hypoglycemia Associated Autonomic Failure in Type 1 DM, Q4 Interventions: Drug: epinephrine|Drug: epinephrine URL: http://ClinicalTrials.gov/show/NCT00608816 Title: Hypoglycemia Associated Autonomic Failure in Type 1 DM, Q5 Interventions: Drug: epinephrine|Drug: epinephrine URL: http://ClinicalTrials.gov/show/NCT00605774 Title: Biomarkers of Risk of Parkinson Disease Conditions: Parkinson Disease|Autonomic Nervous System Diseases|Pure Autonomic Failure URL: http://ClinicalTrials.gov/show/NCT00775853 Title: Abdominal Compression in Orthostatic Hypotension Conditions: Autonomic Failure|Orthostatic Hypotension Interventions: Device: Abdominal binder|Device: No abdominal binder URL: http://ClinicalTrials.gov/show/NCT01223391 Title: Autonomic Phenotype Before and After Akt Inhibition Interventions: Behavioral: Autonomic Function Tests|Other: supine and standing catecholamines URL: http://ClinicalTrials.gov/show/NCT01593579 Title: Assessment of Hand-grip in the Prevention of Postural Orthostatic Hypotension Interventions: Other: Hand grip maneuver URL: http://ClinicalTrials.gov/show/NCT01521221 Title: Intravenous Norepinephrine for Orthostatic Hypotension Interventions: Drug: Intravenous Norepinephrine Infusion URL: http://ClinicalTrials.gov/show/NCT01285908 Title: Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy Conditions: Autoimmune Autonomic Ganglionopathy (AAG) Interventions: Drug: Intravenous Immunoglobulin|Drug: Intravenous Immunoglobulin URL: http://ClinicalTrials.gov/show/NCT01522235 Title: Fipamezole in Neurogenic Orthostatic Hypotension Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH)|Parkinson's Disease|Multiple System Atrophy Interventions: Drug: Placebo|Drug: Fipamezole URL: http://ClinicalTrials.gov/show/NCT00758849 Title: Risk Prediction in Type II Diabetics With Ischemic Heart Disease Conditions: Type-2 Diabetes Mel itus|Ischemic Heart Disease URL: http://ClinicalTrials.gov/show/NCT01422057 Title: Recurrent Hypoglycaemia in Type 1 Diabetes URL: http://ClinicalTrials.gov/show/NCT01337362 Title: Alemtuzumab, Fludarabine, and Busulfan Followed By Donor Stem Cel Transplant in Treating Young Patients With Hematologic Disorders Conditions: Congenital Amegakaryocytic Thrombocytopenia|Diamond-Blackfan Anemia|Leukemia|Myelodysplastic Syndromes|Severe Congenital Neutropenia Interventions: Biological: alemtuzumab|Drug: busulfan|Drug: cyclosporine|Drug: fludarabine phosphate|Drug: methotrexate|Drug: methylprednisolone|Procedure: al ogeneic bone marrow transplantation|Procedure: al ogeneic hematopoietic stem cel transplantation|Procedure: peripheral blood stem cel transplantation|Procedure: umbilical cord blood transplantation URL: http://ClinicalTrials.gov/show/NCT00301834

Source: http://www.dysautonomiasos.org/clinicaltrials/ClinicalTrialsPAF.pdf