Curriculum vitae

Pablo Perel
Personal Particulars
Birth date: November 4, 1967
Nationality: Argentine
Professional Experience:

2011-present: Coordinator Centre for Global Non Communicable Diseases, London School of
Hygiene & Tropical Medicine.
2011-present: Senior Clinical Lecturer, Nutrition and Population Health Intervention Research
Department, Epidemiology and Population Health Faculty, London School of Hygiene &
Tropical Medicine.
2007-2011: Clinical Lecturer, Nutrition and Population Health Intervention Research
Department, Epidemiology and Population Health Faculty, London School of Hygiene &
Tropical Medicine.

2005-2007: Research Fellow, Nutrition and Population Health Intervention Research
Department, Epidemiology and Population Health Faculty, London School of Hygiene &
Tropical Medicine.
2000-2003: Epidemiologist Consultant, United Nations Program, Vigia Program, Health
Ministry, Buenos Aires, Argentina.

1998-1999 Chief of Cardiology Fellows (Hospital de Clínicas de Buenos Aires, Argentina)

1992-1995: Residence in Internal Medicine (Hospital Español, Buenos Aires,
Argentina)
Graduate studies
Medical Doctor (Universidad de Buenos Aires, Argentina)
Honour degree (Equivalent to First Class)
Year of graduation: 1991
Postgraduate studies
2005-2009-: PhD in Clinical Epidemiology (London School of Hygiene and Tropical
Medicine, London United Kingdom)

2003-2004: Masters of Epidemiology (London School of Hygiene and Tropical
Medicine, London United Kingdom) Pass with distinction

1996-1998: Cardiologist specialist (Universidad de Buenos Aires, Argentina.)
Final Mark: 10/10 (Equivalent to First Class)
Selected publications (only last 5 years)

Perel P, Prieto-Merino D, Shakur H, Clayton T, Lecky F, Bouamra O, Russell R,
Faulkner M, Steyerberg E W, Roberts I. Predicting early death in patients with
traumatic bleeding: development and validation of a prognostic model. BMJ 2012
(accepted).
Dewan Y, Komolafe EO, Mejía-Mantilla JH, Perel P, Roberts I, Shakur H.Trials. 2012;
13(1):87.
Ker K, Edwards P, Perel P, Shakur H, Roberts I.BMJ. 2012; 344:e3054.
Ker K, Kiriya J, Perel P, Edwards P, Shakur H, Roberts I. Avoidable mortality from
giving tranexamic acid to bleeding trauma patients: an estimation based on WHO
mortality data, a systematic review and data from the CRASH-2 trial. BMC Emer Med
2012; (12):3
Holmes MV, Perel P, Shah T, Hingorani AD, Casas JP. Improvements in
pharmacogenetic studies are needed for translation into clinical practice: the case of
CYP2C19 genotype and clopidogrel response. JAMA. 2011; 306:2704-14.
Turner E L, Perel P, Clayton T, Edwards P, Hernández A, Roberts I, Shakur H,
Steyerberg E. Covariate adjustment increases power in randomized controlled trials: an
example in traumatic brain injury. JCE. 2011 (Epub ahead of print)
Perel P, Al-Shahi Salman R, Constain A , Dewan Y , Herrera J, Kawahara T, Lal AP,
Mejía-Mantilla J, Morales C, Morris Z, Prieto-Merino D , Ramana PV, Ravi RR,
Roberts I, Sandercock P, Shakur H, Wardlaw J (CRASH-2 IBS Collaborators) Effect
of tranexamic acid in traumatic brain injury: a nested randomised, placebo controlled
trial (CRASH-2 Intracranial Bleeding Study).2011;343:d3795. doi:
10.1136/bmj.d3795.
Roozenbeek B, Lingsma H, Perel P, Edwards P, Roberts I, Murray G, Maas A,
Steyerberg E. The added value of ordinal analysis in clinical trials: an example in
traumatic brain injury. Crit Care. 2011;15(3):R127.
Guerriero C, Cairns J, Perel P, Shakur H, Roberts I. Cost-effectiveness analysis of
administering tranexamic acid to bleeding trauma patients using evidence from the
CRASH-2 trial. PloS One 2011;6(5):e18987
Roberts I, Shakur H, Afolabi A, Brohi K, Coats T, Dewan Y, Gando S, Guyatt G, Hunt
BJ, Morales C, Perel P, Prieto-Merino D, Woolley T. The importance of early
treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of
the CRASH-2 randomised controlled trial. Lancet. 2011;377(9771):1096-101, 1101.e1-
2.
Ferrante D, Apro N, Ferreira V, Virgolini M, Aguilar V, Sosa M, Perel P, Casas J.
Feasibility of salt reduction in processed foods in Argentina.2011;29(2):69-75.
Rehn M, Perel P, Blackhall K, Lossius HM. Prognostic models for the early care of
trauma patients: a systematic review. Scand J Trauma Resusc Emerg Med. 2011;19:17.
Shakur H, Roberts R, Bautista R, Caballero J, Coats T, Dewan Y, El-Sayed H,
Gogichaishvili T, Gupta S, Herrera J, Hunt B, Iribhogbe P, Izurieta M, Khamis H,
Komolafe E, Marrero MA, Mejía-Mantilla J, Miranda J, Morales C, Olaomi O, Olldashi
F, Perel P, Peto R, Ramana PV, Ravi RR, Yutthakasemsunt S. Effects of tranexamic
acid on death, vascular occlusive events, and blood transfusion in trauma patients with
significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet.
2010; 376(9734):23-32. .
Guerriero C, Cairns J, Jayaraman S, Roberts I, Perel P, Shakur H.Cost
Eff Resour Alloc. 2010 ;8(1):1.
Perel P, Roberts I, Bouamra O, Woodford M, Mooney J, Lecky F. Intracranial bleeding
in patients with traumatic brain injury: a prognostic study. BMC Emerg Med. 2009 Aug
3;9:15.
Bautista LE, Casas JP, Herrera VM, Miranda JJ, Perel P, Pichardo R, González A,
Sanchez JR, Ferreccio C, Aguilera X, Silva E, Oróstegui M, Gómez LF, Chirinos JA,
Medina-Lezama J, Pérez CM, Suárez E, Ortiz AP, Rosero L, Schapochnik N, Ortiz Z,
Ferrante D; Latin-American Consortium of Studies in Obesity (LASO)Obes Rev. 2009 May;10(3):364-
70.
Herrera VM, Casas JP, Miranda JJ, Perel P, Pichardo R, González A, Sanchez JR,
Ferreccio C, Aguilera X, Silva E, Oróstegui M, Gómez LF, Chirinos JA, Medina-
Lezama J, Pérez CM, Suárez E, Ortiz AP, Rosero L, Schapochnik N, Ortiz Z, Ferrante
D, Diaz M, Bautista LE. Interethnic differences in the accuracy of anthropometric
indicators of obesity in screening for high risk of coronary heart disease Int J Obes
(Lond). 2009 Feb 24
De Silva MJ, Roberts I, Perel P, Edwards P, Kenward MG, Fernandes J, Shakur H,
Patel V; on behalf of the CRASH Trial Collaborators. Patient outcome after traumatic
brain injury in high-, middle- and low-income countries: analysis of data on 8927
patients in 46 countries. Int J Epidemiol. 2008 Sep 9. [Epub ahead of print]
How effective are some common treatments for traumatic brain injury?2008 Aug 14;337:a865. doi: 10.1136/bmj.a865 Habbema JD,Predicting outcome after traumatic brain injury: development and international validation of prognostic scores based on admission characteristics.2008 Aug 5;5(8):e165 Perel PRelation between the global burden of disease
and randomized clinical trials conducted in Latin America published in the five leading
medical journals2008 Feb 27;3(2):e1696.
Perel P, Arango M, Clayton T, Edwards P, Komolafe E, Poccock S, Roberts I, Shakur
H, Steyerberg E, Yutthakasemsunt S. Predicting outcome after traumatic brain injury:
practical prognostic models based on large cohort of international patients BMJ. 2008
Feb 23;336(7641):425-9. Epub 2008 Feb 12.
Editorial membership in Medical Journals
Editor Cochrane Heart Group 2012
Associate Editor Trials Journal 2012
Associate Editor BMC Medical Research Methodology 2011-present
Editor Cochrane Injuries Group 2005-present
Main teaching Experience:

Course Organizer Reporting and Reviewing Clinical Trials Master in Clinical Trials
LSHTM 2011- present
Course Organizer Systematic Reviews and Meta-Analyses of Health Research LSHTM
2010- present
Course Organizer Non-Communicable Epidemiology, Master of Epidemiology
by Distance Learning London School of Hygiene & Tropical Medicine 2005-2009
Selected grants

Principal investigator Health Technology Assessment (HTA): Development and
validation of a risk score for trauma patients with haemorrhage The CRASH-2 score
Total amount: £140,022 (1/10/2010 to 31/03/2012)
Co-applicant Medical Research Council: Partnership Grant for Prognostic Research A
Strategic Initiative in Translational Pathways (PI at LSHTM) Total amount £807,318
(1/01/2012 to 31/12/2014)

Source: http://www.cedes.org/Cv_Perel_IDRC2012.pdf