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Welcome to Clinical Trials Update from the UC Health Clinical Trials Office. This e-newsletter features information about clinical trials, or research studies, that you or a family member may be able to participate in at UC Health. A research study to understand how weight loss surgery changes glucose metabolism
Have You Had Weight Loss Surgery?
This NIH funded research study is investigating neural and hormonal factors that control blood sugar. Insulin is the main hormone that
controls the level of glucose in the blood; and factors such as neurological activity, as well as gut hormones, change the insulin
response to meal ingestion. This study will help us better understand the effects of weight loss surgery on blood glucose levels and
insulin response to intestinal hormones as well as neural activity.
Men and women ages 18 to 65 who had weight loss surgery such as gastric bypass, lap-band, or sleeve gastrectomy, and are free of
any gastrointestinal obstruction, are eligible to participate.

Participants may be compensated for time and travel expenses related to each study visit they complete. Participants will receive
information on glucose metabolism and diabetes that may be
For more information, call Leslie Baum at 513-558-0201 or via email at [email protected] Adults 18 and Older Needed for a Medication Research Study
Do you have epilepsy? Do you take the drug lamotrigine on a daily basis?
The purpose of this research study is to test two different generic versions of the medication lamotrigine and to see if they perform in a similar way when given to people with epilepsy every day over a period of several weeks. The two different generic versions of the study drug lamotrigine are both approved by the United States Food and Drug Administration (FDA) for the treatment of seizures. Adults 18 years and older who have epilepsy and take lamotrigine daily may be eligible to participate. Participants will receive up to $1150 for study related time and travel.

For more information, contact Lucy Mendoza at [email protected] or 513-558-3020.
Is it hard to control your symptoms using your current medication?
Do You Have Ulcerative Colitis?
This study will evaluate whether the study medication, budesonide MMX®, is safe and effective in people with ulcerative colitis that is not well controlled using anti-inflammatory medications known as 5-aminosalicylic acids (5-ASAs). Budesonide MMX®, is approved by the United States Food and Drug Administration (FDA). This study is looking to see whether budesonide MMX® (given by mouth as tablet) and 5-ASA medication used together can better control the symptoms of ulcerative colitis. Adults 18-75 years old who have been diagnosed with mild or moderate ulcerative colitis (UC) and continue to have symptoms even when taking a 5-ASA medication (such as Asacol® and Lialda®) to treat UC. Participants will be compensated for time and travel. All medication will be provided at no cost to participants. For more information, contact Lauren Plageman at 513-558-5529 or [email protected] We need you for an observational research study.
Are you pregnant? Do you have epilepsy?
The purpose of this observational research study is to establish the risk for problems during pregnancy for women who have epilepsy and determine the factors or contributions to those risks. In addition, the children of these women with epilepsy will be evaluated to determine possible cognitive adverse effects from seizures or medications. Most women with epilepsy have normal pregnancies, but appear to be at risk for problems during pregnancy (like seizures, change in medications, depression, C-sections) and adverse outcomes in their children (thinking or behavioral problems). We hope the information learned from this research study will benefit patients with epilepsy in the future. Are currently pregnant in their first trimester Do not have any active drug or alcohol abuse or major medical disease such as cancer Participants will be paid for study related time and travel.

For more information, contact Lucy Mendoza at [email protected] or 513-558-3020.
Adults 18 and older needed for a single dose medication research study.
Do you have epilepsy and are not taking drug lamotrigine?
The purpose of this research study is to determine whether two different generic versions and the brand version of the medication lamotrigine will perform in a similar way when given to people with epilepsy as a single dose once every two weeks in a period of twelve weeks. The study drug Lamictal® (brand) and both of the two generic versions of lamotrigine are approved by the United States Food and Drug Administration (FDA) for the treatment of seizures. Adults 18 years and older who have epilepsy and are not taking lamotrigine may be eligible to participate. Participants will receive up to $1975 for study related time and travel. For more information, contact Lucy Mendoza at [email protected] or 513-558-3020. Antiretrovial Therapy (ART) Investigational Research Study
Do You Have HIV? Do You Manage to Control the Virus Without the Use of Drugs?
This is a research study to see if antiretroviral therapy (ART), an HIV medication, will reduce immune activity (the body’s way of fighting disease) in people who have HIV but do not show any symptoms. This study will also help determine how safe the drug is and how well the body reacts to the medication. Adults 18 years or older who are infected with HIV, but do not show any signs of having HIV, and are doing well without taking HIV medication may be eligible to participate. Participants will not be paid for their time in this study. For more information, contact Tammy Miller Mansfield at 513-584-8373. This email was sent by the UC Health Clinical Trials Office

Source: http://uchealth.com/wp-content/uploads/sites/3/2013/06/UC-Enews-June-2013.pdf

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C l u st e r o f i m p o rt e d m a l a r i a f r o m G a m b i a i n f i n l a n d – t r av e l l e r s d o n ot l i st e n to G i v e n a dv i C eK Valve ([email protected])1, E Ruotsalainen1, T Kärki1, E Pekkanen1, H Siikamäki21. National Public Health Institute, Department of Infectious Disease Epidemiology and Control, Helsinki, Finland2. Helsinki University Central Hospital, Division

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